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EP Masterclass > EP studies > Flashcards

EP studies Flashcards

1
Q

Normal HV interval

A

35-55ms

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2
Q

Short HV indicates

A

AP

HV usually 0 or can be negative

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3
Q

Long HV indictes

A

infra-HIS disease

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4
Q

Normal AH interval

A

50-120ms

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5
Q

Long AH indicates

A

AV block

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6
Q

AH is

A

time travelled through AVN

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7
Q

HV is

A

exit from AVN to entrance of HIS system

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8
Q

HV is measured on

A

H on HIS channel and earliest V on HIS channel

*alternate - His on CS and Earliest V on surface ECG

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9
Q

AH is measured on

A

A and H on His channel

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10
Q

First test in EP study

A

IVP (incremental ventricular pacing)

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11
Q

Order of tests in EP study

A

IVP
Retrograde curve
IAP
Antegrade curve

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12
Q

Ventricular testing stop point

A

Wenckebach point or 300ms

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13
Q

Principle observations of ventricular testing during EP study (SR)

A
  • Wenckebach point – cycle length at which 1:1 VA conduction stops
  • Pattern of retrograde atrial activation
    Eccentric (up another way other than AVN)
    Concentric (up AVN)
  • Timing of retrograde atrial activation (if any)
    Fixed = AP
    Decremental = AVN
    e.g. What is dominant in retrograde conduction - AVN or AP (if present)

(if AVN first, then when AVN becomes refractory does AP conduct retrogradely?; if AP first, then what rate does AP become refractory – does it change after ablation?)**

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14
Q

Principle observations of atrial testing during EP study (SR)

A
  • Antegrade conduction properties of AVN and HIS purkinje system
  • Wenckebach point – cycle length at which 1:1 conduction over AVN stops
  • AH jump = dual nodal physiology (curve)
  • Ventricular pre-excitation via AP (increase of pre-excitation)
  • Arrhythmia induction
  • antegrade pathway conduction rate >240ms unsafe
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15
Q

Diagnosis of PSVT depends on what 3 elements?

A

a. baseline findings prior to tachycardia initiation
b. tachycardia characteristics
c. tachycardia response to atrial and ventricular pacing manoeuvres

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16
Q

Testing during tachy:
What is entrainment?

A

Vp at a cycle length 20ms faster than ongoing tachy. Stop pacing and ensure tachy continues after pacing terminates.
Measure first captured V stim to stim and compare to last A-A to see atrial rate now matches Vp rate.

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17
Q

Testing during tachy:
Determine response to entrainment

A

VAAV - AT
VAV - AVNRT or AVRT
Pseudo VAAV - atypical AVNRT or ORT with slow conducting pathway

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18
Q

What does the VAAV entrainment response mean?

A

AT - both antegrade and retrograde conduction occurs via AVN so last entrained atrial beat hits a refractory AVN

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19
Q

What does the VAV entrainment response mean?

A

AVNRT or AVRT - entrainment of atrium due to retrograde conduction over the ascending limb of AVNRT (regardless of type of AVNRT) or up the AP i.e. ORT then antegrade down the AVN

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20
Q

Testing during tachy:
What does it mean if tachy terminates during entrainment?

A
  • Termination of tachy without affecting the atrium excludes AT i.e. end with a V
  • Tachy ends with A – likely AVRNT or AVRT
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21
Q

Testing during tachy:
What is HIS sync VPBs?

A

Vp delivered at a time that the HIS is refractory during SVT.
The only way for the Vp impulse to continue is via an AP as conduction up the AVN is blocked.

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22
Q

Testing during tachy:
Explain respone to HIS sync VPBs

A
  • No change in AA timing – **excludes right sided AP **
  • Atrial advancement with resetting (with same atrial activation) – AP present and contributes to SVT mechanism = ORT
  • Atrial advancement without resetting (with same atrial activation) – **AVNRT with bystander AP **
  • Atrial advancement with different atrial activation sequence - bystander AP
  • Atrial post excitation – **decrementally conducting AP (Mahaim) and ORT **
  • Termination of SVT – **ORT **
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23
Q

Testing during tachy - HIS sync VPBs :
No change in AA timing means?

A

if AA changed, the only way for it to reach atrium that quickly would be because of an AP that conducts retrogradely = exclusion of right sided AP

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24
Q

Testing during tachy - HIS sync VPBs :
Atrial advancement with resetting means?

A

next A is advanced, which subsequently advances next HIS and V = AP that contributes to SVT mechanism is present i.e. ORT

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25
Q

Testing during tachy - HIS sync VPBs :
Atrial advancement without resetting means?

A

no reset means next A is advanced but doesn’t advance next HIS and V = AVNRT with bystander AP

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26
Q

Testing during tachy - HIS sync VPBs :
Atrial advancement with different atrial activation sequence means?

A

e.g. from concentric to eccentric or 9-10 first to 5-6 first = bystander AP

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27
Q

Testing during tachy - HIS sync VPBs :
Atrial post excitation means?

A

delay of next A after HIS sync VPB - ORT or decremental AP

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28
Q

Testing during tachy - HIS sync VPBs :
Termination of SVT

A

ORT

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29
Q

What is the problem when a wobble is present?

A

Teating during SVT tachy with wobble (variations in cycle length more than 30ms) is un-useful.

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30
Q

Testing during tachy:
What is post pacing interval (PPI)?

A

Used to differentiate between atypical AVNRT and AVRT that uses a septal AP.

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31
Q

Testing during tachy:
How is PPI measured?

A
  • Perform entrainment.
  • Measure from last Vp beat to first return to tachy i.e. PPI
  • Then Measure tachy cycle length after pacing cessation i.e. TCL
  • Do PPI – TCL calculation.

If <115ms = AVRT; > 115ms = AVNRT

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32
Q

Testing during Sinus:
What is para-HISian pacing?

A

Testing used to exclude presence of septal AP

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33
Q

Testing during Sinus:
How is Para-HISian pacing measured?

A
  1. Pace at high outputs to get narrow QRS as capturing AVN, HIS and RV.
  2. Drop outputs quickly to capture only RV (Broad QRS).
  3. Measure and compare VA intervals of Broad and Narrow complexes.
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34
Q

Testing during Sinus:
Response to Para-HISian testing?

A
  • Nodal response – AP not present. VA time remains unchanged between Narrow to Broad QRS (does not exclude left sided pathways)
  • Extranodal response – Concealed AP present. VA time is shorter between Narrow to Broad QRS
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35
Q

What does the presence of BBB during tachycardia means?

A

Does the VA time change?

  • AP present, VA will increase during BBB because impulse now has to travel to unblock bundle branch before blocked one, and then back up to atrium to conduct as a circuit.
  • no AP present, VA time will remain the same between narrow and blocked beats
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36
Q

What is determined during EP testing?

A

a) Antegrade and retrograde conduction properties of AVN/AP/ANVRT
b) If present, is AP/AVNRT safe?
c) Allows for SVT?

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37
Q

In Concentric atrial activation, where is A seen first on the CS channel?

A

channel 9-10

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38
Q

In eccentric atrial activation, where is A seen first on the CS channel?

A

Can be anywhere on CS channel depending on diagnosis and localisation

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39
Q

Ventricular pacing manuvers during Sinus:
How is a retrograde curve performed?

A

8 beat drive train follwed by extrastimulus with shorter coupling intervals that decrement during decrement until wenckebach point or 300ms.

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40
Q

Why is retrograde testing important for APs?

A

Majority of AP conduct retrogradely i.e. orthodromic AVRT

Down the AVN up the pathway = Narrow tachycardia

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41
Q

Atrial pacing manuvers during Sinus:
How is incremental atrial pacing performed?

A
  1. Start Ap at a rate faster than Sinus cycle length (500 or 400ms)
  2. Slowly increase the pacing rate (- button) until wenckebach point or 200ms
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42
Q

What does it mean if the on the MAP channels signals on channel 3-4 are seen to be ahead of signals on channel 1-2?

A

The ablation tip (channel 1-2) has gone past the hot spot

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43
Q

What is the advantage of using adenosine?

A

Expect VA and AV block which allows for hyperpolarisation of AP if still present before or after ablation

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44
Q

In AVNRT and AVRT what catheter is the reference?

A

CS catheter

because SVTs of this origin occur near the CS and thus the CS catheter is used to bracket the surrounding area; therefore can be used as a reference i.e. distance from CS catheter to hotpoint.

If looking for AT of different origin (e.g. not close to CS) then reference would be placed elsewhere e.g. HRA

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45
Q

During IVP, VA conduction shows concentric atrial activation with decrement. What does this mean?**

A

Retrograde conduction up the AVN.

*If AP is present then it does not conduct retrogradely or fused i.e. up the pathway, so down the AVN - Orthodromic (Narrow)

46
Q

During IAP, conduction shows concentric atrial activation with decrement. What does this mean?

A

Antegrade conduction down the AVN.

*If AP is present then it does not conduct antegrade or fused i.e. down the pathway, so up the AVN - Antidromic (Broad)

47
Q

During IVP, VA conduction shows eccentric atrial activation without decrement. What does this mean?

A

Retrograde conduction up the pathway

*If AP is present then it does conduct retrogradely i.e. up the pathway, and down the AVN - Orthodromic (Narrow)

48
Q

During IAP, conduction shows eccentric atrial activation without decrement. What does this mean?

A

Antegrade conduction down the pathway.

*If AP is present then it does conduct antegrade i.e. down the pathway, up the AVN - Antidromic (broad)

49
Q

Define Eccentric activation

A

atrial activation other than by AV node during V pacing
or early activation of ventricle during A pacing

50
Q

Define concentric activation

A

normal AVN activation of atria

*earliest atrial activation on HIS catheter first

51
Q

Define VERP

A

No capture of Ventricles with Vp

52
Q

Define VAERP

A

VA conduction becomes refractory

53
Q

What is the stop point for atrial testing?

A

Wenckebach point or 200ms

54
Q

Define AERP

A

LOC during Ap

55
Q

Define AVNERP

A
56
Q

Define Wenckbach CL

A
57
Q

Purpose of IVP

A

Discover what retrograde routes connecting ventricles to atria are available for impulse conduction

No VA conduction suggests lack of VA connection via AVN or AP and AT is more likely

58
Q

During ablation of AVNRT, what ablation catheter and method is used?

A

Non-irrigated 4mm tip ablation catheter
Nibble method

For less deep burn as close to AVN

59
Q

A sudden increase in PR interval during PAC or atrial pacing suggests what?

A

Shift in anterograde conduction from fast to slow pathway (AH jump).

*PAC blocks in refractory fast pathway (reaches its refractory point) but still conducts to AVN via slow pathway

60
Q

An AH jump is defined as what during an Antegrade curve?

A

> 50ms increase in AH interval

*An AH jump only proves presence of dual nodal physiology, not definitely prove their SVT is AVNRT

61
Q

Define AV nodal echo beat

A

One beat of non-sustained tachycardia caused by anterograde conduction via the slow pathway. and subsequent retrograde activation via the fast pathway

62
Q

Conventional ablation therapy for AVNRT is what?

A

slow pathway modification

*aim to disrupt tachycardia substrate by ablating slow pathway and changing conduction properties.

63
Q

What can indicate the operator is on the wrong site for ablation during AVNRT cases?

A

HIS signal on ablation catheter (Map)

64
Q

Ablation of AVNRT is performed during which rhythm?

A

Sinus Rhythm
​
*to increase stability of catheter and monitor AV association

65
Q

What rhythm should be elicited during the first 15s of ablation?

A

Junctional Rhythm

*Accelerated junctional rhythm >120bpm could suggest ablation of fast pathway or AVN which increases risk of CHB

66
Q

What targets for ablation can be seen on the Map catheter to indicate good contact with the slow pathway?

A

Large V signal
Small A signal
No HIS signal

67
Q

**

Identify the primary endpoints for AVNRT ablation

A

complete elimination or modification of slow pathway assessed by:

  • Presence of slow Junctional rhythm during ablation
  • Non inducibility of AVNRT
68
Q

During retrograde curve, where are u measuring from using the callipers?

A

Stim to earliest A on CS

69
Q

During antegrade curve, where are u measuring from using the callipers?

A

A capture on CS to HIS/earliest V on surface ECG

70
Q

Differential diagnosis for a wide complex tachycardia with RBBB and long RP in tachycardia

A
  1. atypical (fast-slow) AV nodal reentrant tachycardia
  2. orthodromic reciprocating tachycardia
  3. atrial tachycardia with an underlying bundle branch block
71
Q

Identifying AP location:
V1/V6

A

LBBB = right sided (Bigger S wave in V1)
RBBB = left sided (Bigger R wave in V1)

72
Q

Identifying AP location:
Transition in chest leads

A

Early (by V2/V3) = septal
Late (V3 and onwards) = lateral

73
Q

Identifying AP location:
Inferior leads (aVR, II,III)

A

All neg = posterior
All Pos = Anterior
Mismatch = midline

74
Q

In Manifest AP, what direction do they predominantly conduct?

A

Orthodromic

75
Q

Orthodromic AVRT has a long or short RP?

A

short

can be long if accessory pathway is slow

76
Q

ECG charateristics of Orthodromic AVRT tachycardia

A

Normal narrow QRS complexes
150-250bpm
Visible P wave (retrograde in inferioe lead and after QRS)
Short RP (long PR)

77
Q

Antidromic AVRT has a long or short RP?

A

Long

78
Q

ECG charateristics of Antidromic AVRT tachycardia

A

Wide complex QRS (visible delta)
150-250bpm
No visible p wave (but retrograde and before QRS)
Long RP

79
Q

Adenosine

A

short acting antiarrhythmic
causes depression of SA and AV nodal acitivty
diagnosis and treatment of paroxysmal SVT

80
Q

Contraindications of adenosine

A

second and third degree AV block
allergy
care with asthma and COPD

81
Q

define concordance

A

all QRS complexes from Lead V1 to V6 are in the same direction; either all positive or all negative

Any biphasic QRS complexes (qR or RS) means no concordance.

81
Q

Negative concordance suggests?

A

VT

82
Q

Positive concordance suggests?

A

VT or antidromic AVRT

83
Q

Why should adenosine not be administered for suspected VT?

A

Andenosine in VT can accelerate the frequency and aggravate the arrhythma.

If suspected SVT and adenosine is administered and the response is no effect or tachy acceleration then likely VT

84
Q

Identify the 5 criteria of the Brugada algorithm for differentiating VT from SVT.

A

1.

85
Q

Nodal response during Para-HISIAN pacing

A

VA time remains unchanged between Narrow to Broad QRS (does not exclude left sided pathways)

I.e. no AP present

86
Q

What is extra-nodal response during Para-Hisian pacing?

A

VA time is shorter between Narrow to Broad QRS

I.e. Concealed AP present.

87
Q

Chest leads look at what region of the Heart for AP localisation?

A

Where it is septal or lateral
V1/V6 indicate right or left sided

88
Q

Inferior leads reference what area in regards to AP localisation?

A

Posterior, Anterior, midline

89
Q

What are the 4 regions of left sided free wall pathways?

A

Left anterolateral (LAL)
Left lateral (LL)
Left posterolateral (LPL)
Left posterior (LP)

90
Q

What are the 5 regions that right free wall pathways can arise?

A

Right anterior (RA)
Right anterolateral (RAL)
Right lateral (RL)
Right posterolateral (RPL)
Right posterior (RP)

91
Q

Wenchebach CL is found during what tests?

A

IAP & IVP

92
Q

ERP is found during what tests?

A

Curves

93
Q

Posterior

A

Back of heart

94
Q

Anterior

A

Front of heart

95
Q

Superior

A

Top

96
Q

Inferior

A

Bottom

97
Q

No VA conduction during retrograde testing suggests?

A

No retrograde conduction - either no AP present or AP conduction is sluggish

98
Q

AVNRT ablation catheter

A

Navistar irrigated

99
Q

End point criteria for AVNRT slow pathway ablation

A

No jump
No echo
Slow pathway block

100
Q

What are the characteristics of automatic tachycardias?

A

Warm up and cool down in rate
Metabolic causes e.g. ischemia, hypoxemia, hypokalemia

101
Q

Name a type of automatic tachycardia

A

Atrial tachycardia

102
Q

Name a type of tachycardia that is considered to be re-entry and why

A

AVNRT

because it meets the criteria of re-entry tachycardias with 2 pathways connected proximally and distally that have different conduction and refractory properties

103
Q

What is triggered activity

A

A leakage of positive ions into the cardiac cell causing a bump in phase 3 or 4 of the cardiac action potential = after depolarisation.

If they are big enough to engage the rapid sodium channels another action potential can be generated

104
Q

Long RP tachycardia

A

ORT
Atypical AVNRT

105
Q

Repetitive V response

A

critical coupling intervals during ventricular extrastimulus testing (S2) can be followed by ventricular responses similar in morphology and axis to the paced beat.

106
Q

RVOT paced morphology on ECG

A

LBBB (in chest leads all negative)
Positive inferior leads (avL negative)

107
Q

RV apex paced morphology

A

LBBB in chest leads (all negative)
Negative in inferior leads (avL positive)

108
Q

LBBB during ORT means what?

A

Left sided AP - longer VA

Right sided AP - Same or short VA

109
Q

RBBB during ORT

A

Left sided AP - same or short VA

Right sided AP - longer VA

110
Q

Ablation settings for AVNRT

A

30-35 degrees
50-55 degrees

111
Q

When to tell operator to stop during AVNRT ablation

A

EP Masterclass (5 decks)

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