Evolution Week 9 - Fitness& Pleiotropy Flashcards

1
Q

Define fitness

A

The survival and reproductive success of an individual with a particular phenotype.

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2
Q

What are 3 components of fitness?

A

Survival to reproductive age
Mating success
Fecundity

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3
Q

Define relative fitness (w).

A

Contribution of individuals with one genotype compared with the average contribution of all individuals in the population.

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4
Q

Define pleiotropy.

A

Mutation in a single gene affects more than one phenotypic trait.

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5
Q

Define antagonistic pleiotropy.

A

Beneficial effects for one trait but detrimental effects for other traits.

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6
Q

The net effect on fitness determines what?

A

The outcome of selection.

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7
Q

Alleles may have pleiotropic effects when…

A

Fitness effects oppose each other and when the environment determines direction of selection.

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8
Q

Define negative selection.

A

Alleles that lower fitness
experience.

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9
Q

Define positive selection.

A

Alleles that increase fitness
experience.

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10
Q

Define additive alleles.

A

Homozygous condition yields twice the phenotypic effect for the gene as compared with heterozygotes.

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11
Q

Define dominance.

A

Dominant allele masks presence
of recessive in heterozygote.

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12
Q

Which alleles are especially vulnerable to the action of selection? Why?

A

Additive alleles.

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13
Q

Define negative frequency-dependent selection. Give an example.

A

Common phenotypes are selected
against, and rare phenotypes are favored. Ex. Female guppies prefer to mate with males that have rare phenotypes.

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14
Q

Define heterozygote advantage. Give an example.

A

Heterozygosity confers greater fitness than homozygotes.

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15
Q

What are two balancing selections?

A

Negative frequency-dependent and heterozygote advantage.

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16
Q

Give the formula for phenotype plasticity.

A

Vp = Vg + Ve
p - phenotypic variance in population
g - variance due to genetic differences
e - variance due to environmental differences

17
Q

Define phenotype plasticity.

A

A single genotype produces
different phenotypes depending
on the environment.

18
Q

Which multiply faster between asexual and sexual lineages?

A

Asexual lineages multiply
faster than sexual lineages.

19
Q

What are some consequences of sexual reproduction?

A

Twofold cost of sex
Search cost
Reduced relatedness
Risk of sexually transmitted infections

20
Q

What are some advantages of sexual reproduction?

A

Combining Beneficial Mutations
Generation of Novel Genotypes
Faster Evolution
Clearance of Deleterious Mutations

21
Q

What are some limitations of asexualy reproduction?

A

Muller’s rachet: genomes of an asexual population
accumulate irreversible, deleterious mutations over
generations
Genetic load: he burden of accumulated deleterious
mutations increases over time

22
Q

What happens the frequency of deleterious alleles in asexual and sexual populations?

A

Deleterious alleles
become fixed in asexual
populations but are purged
from sexual populations.