EX1; Sensory Physiology Flashcards

1
Q

Unique experience associated with a particular modality beings where

A

at a receptor

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2
Q

Initial interaction of stimulus with receptor is this; transformation of physical energy into neural signal

A

transduction

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3
Q

The type of energy that a given receptor type is most sensitive to is called what

A

adequate stimulus

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4
Q

Sensory specificity is due to what

A

limited sensitive range of a receptor

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5
Q

This law states that central connections determine modality like; stimulation of optic nerve bypassing receptors - light, stimulation of auditory nerve bypassing receptor - sound

A

Law of Specific Nerve Energies

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6
Q

What are the 5 types of sensory receptors

A
mechanoreceptors
thermoreceptors
photoreceptors
chemoreceptors
nociceptors
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7
Q

Somatosensory uses what types of sensory receptors

A

mechano
thermo
chemo
noci

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8
Q

Olfaction and taste uses what type of sensory receptor

A

chemo

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9
Q

Vision uses what type of sensory receptor

A

photo

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10
Q

Audition and balance uses what type of sensory receptor

A

mechano

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11
Q

A physical (direct) interaction of stimulus with membrane protein opens up what

A

ion channels; somatosensory, vestibular, auditory, taste

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12
Q

A molecular interaction of stimulus with a membrane proteins involves what

A

G-protein; vision, taste, olfaction

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13
Q

What are the three steps of direct transduction in the taste system

A
  1. Na enters through epithelial Na channels
  2. action potentials lead to Ca entry
  3. release of ATP as neurotransmitter
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14
Q

What are the three steps of molecular G-protein couples transduction for “sweet” stimuli

A
  1. sugars bind to receptor coupled G-protien
  2. release of intracellular Ca activates TRPm5 channel (transient receptor potential)
  3. depolarization leads to action potentials and release of neurotransmitter ATP
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15
Q

This is a family of ion channels first found in Drosophila comprised of 6 transmembrane domains with a channel between the 5th and 6th

A

transient receptor potentials channels (TRP)

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16
Q

Which ion do TRP channels pass with a large variety of activating mechanisms

A

Ca

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17
Q

What 7 things can open different TRP channels

A
intracellular Ca
temperature
chemicals
sounds
light
pH and osmolarity
mechanical
18
Q

The increase of these three things codes for intensity

A

increase in stimulus intensity
increase in receptor potential
increase in # of action potentials

19
Q

The relationship between stimulus intensity and neural and perceptual responses is sometimes what

A

linear

20
Q

This is not a precise value (statistical concept)

A

threshold

21
Q

What is the function of sensitivity of receptors

A

require a stimulus level that produces an action potential

22
Q

Threshold is not only a function of the stimulus, it can also be affected by what

A

psychological, neurological, or pharmacological factors

can be useful diagnostic tool

23
Q

This is what a receptor (or neuron) is sensitive to

A

receptive field; smaller would be more finer and spatially limited

24
Q

True or False

There is across neuron coding for olfactory quality

A

True; comparing activity across olfactory fibers provides a more or less infinite number of patterns

25
Q

What two types of duration does a sensory stimulus undergo

A

rapidly adapting

slowing adapting

26
Q

This also plays a role in the location of the sensory stimulus

A

lateral inhibition

27
Q

This type of inhibition is where a hyperpolarized axon terminal leads to less Ca entry and less neurotransmitter release

A

presynaptic inhibition

28
Q

This type of inhibition is where EPSPs and IPSPs interact; spatial and temporal summation

A

postsynaptic inhibition

29
Q

What are the 5 steps of the auditory pathway

A
  1. hair cells (receptor cells) in cochlea
  2. innervation by VIII nerve
  3. VIII nerve synapses with cochlea nuclei
  4. ascending sensoy pathway to cortex
  5. efferent pathway from superior olivary nuclei
30
Q

This has the descending pathway to auditory receptor cell

A

superior olivary nuclei

31
Q

Efferents from the superior olive synapse on what and functions to what

A

hair receptor cells

functions to “set gain” of receptor neuron

32
Q

The efferent synapse from the superior olive is on what

A

inhibitory nicotinic receptor; Caa activated K channel leads to hyperpolarization

33
Q

The somatotopic map (homunculus) involves what

A

body representation

34
Q

The tonotopic map involves what

A

auditory pitch representation

35
Q

The retinotopic map involves what

A

visual field representation

36
Q

The peripheral receptor density (in homunculus) is represented centrally by what

A

spatial extent

37
Q

What are the two sensory maps that are dynamic (plasticity)

A

experience

neurological injury

38
Q

There is evidence to support increased cortical representation of the fingers of the left hand in which type of people

A

string players

39
Q

What things are involved with the dynamic sensory map of experience

A

synaptic efficacy; long tern potentiation
new synapses
loss of inhibition

40
Q

What thing is involved with the dynamic sensory map of neurological experience

A

collateral sprouting