Exam 1 Flashcards
GABA
Neurotransmitter that inhibits brain signals
Glutamate
Brain’s most abundant excitatory neurotransmitter
Fraternal vs Identical Twins
Fraternal twins are no more similar than siblings. Identical twins have identical genes
Concordance rate of Depression between fraternal and identical twins
Fraternal: 15%
Identical: 67%
Concordance rate of anxiety between fraternal vs identical twins
Fraternal: 4%
Identical: 40%
Aside from genetics, identical twins also have ______. This means that concordance between certain mental disorders can be attributed to more than just genetics
Super-shared environment
Number of neurons in your brain
~100 billion
Four main components of a neuron
Soma (cell body), dendrites, axon, myelin
Nodes of Ranvier
Gaps in the myelin sheath that allow signals to skip and go faster
Terminal Button
Endpoint of the axon
Can your body make new neurons?
Generally, no
Gila
Support system for the neurons. Much smaller, but much larger in numbers than your neurons
Three major types of neurons
Sensory neurons, motor neurons, interneurons
Stages of impulse transmission
- Synthesis of neurotransmitter
- Storage in synaptic vesicle
- Release into synaptic space
- Binding to receptor site
- Deactivation through reuptake or breakdown
Why don’t neurons touch each other
They would always be active
Nutrients needed to synthesize neurotransmitters
Precursors
How does your body respond to overabundance of neurotransmitters in the synaptic space?
It will create more receptors on your dendrites.
Acetylcholine
Assists with long-term memory and muscle activity
Alzheimer’s Mechanism
Lack of acetylcholine
Botox mechanism
Inhibits reception of acetylcholine
Black widow poison mechanism
Inhibits reception of acetylcholine
Serotonin
Regulates appetites, drives (sex, thirst, sleep), and your long-term mood
Depression mechanism
Too little serotonin and/or norepinephrine
Manic mechanism
Too much serotonin
Antidepressant mechanism
Gives you more serotonin. Decreases GABA
SSRI Mechanism
Prevents reuptake of serotonin (selective serotonin reuptake inhibitor)
Dopamine
Involved in working (short-term) memory, learning, voluntary movement, experiencing salient pleasure, and regulating emotions
Parkinson’s mechanism
Too little dopamine
Schizophrenia
Too much dopamine
Cocaine mechanism
Inhibits reuptake of dopamine
Marijuana mechanism
Increases dopamine levels
Norepinephrine
Involved in attention, mood, fight/flight response, and learning
Anxiety mechanism
Lack of norepinephrine
ADHD mechanism
Inability to inhibit norepinephrine
Epinephrine
Adrenaline. Similar to norepinephrine, but found more in the body
EpiPen mechanism
Epinephrine injection
GABA
Primary inhibitor of neurotransmitters
Alcohol mechanism
Increases GABA
Endorphines
Body’s natural painkillers. Responsible for “euphoria”
Heroin mechanism
Increases endorphines
Main divisions of the nervous system
Central nervous system (brain, spine), peripheral nervous system (everything else)
Divisions of the peripheral nervous system
Somatic and Autonomic