Exam #1 Flashcards
Which has increased during the Global War on Terrorism compared to previous wars?
Disability rates of US active duty personnel
What is the average number of years lost to those who smokes tobacco products?
10yrs
What is average reduction in major coronary heart events, e.g. heart attack, from medical treatment with statins and other drugs?
30%
What is the approximate average reduction in mortality attributable to cardiovascular disease in patients who use a statin for primary prevention of heart disease?
30%
Strict blood sugar control has many benefits for people with diabetes. Which condition has the greatest reduction in incidence with strict blood sugar control?
Diabetic retinopathy
What are the 6 study types?
Experimental, Observational, Ecological, Clinical Trial, Interventional, Descriptive
Uncorrected visual acuity (VA) was measured in 2000 people between the ages of 43 and 86 years in a Montana community. The results showed that VA was better overall in people in their 40s than people in their 80s, and better overall in women than in men. Thus, age (younger) and sex (women) were independent predictive variables of better VA.
What best describes the study type?
Observational
Another study randomly divided the subjects in question 1 (above) into two groups: one group had their visual acuity (VA) measured while wearing their best-corrected prescribed spectacle correction, and the other group had their VA measured without correction. The results showed significantly better overall VAs in the group assigned to spectacle correction versus the control group with no correction. This study showed that accurate spectacle correction improves VA.
What best describes the study type?
Experimental
Researchers interviewed 100 gamers about their daily video game exposure (time spent playing video games per 24-hour period) and also measured each subject’s phoria status. The results showed that subjects who spent more than 12 hours per day playing video games had on average an esophoric posture, whereas those who played less then 1 hour of video games per day had on average an exophoric posture after the gaming period. The study showed that excessive video game exposure was associated with esophoria.
What best describes the study type?
Observational
Another study randomly divided 100 gamers into three groups: Group #1 subjects were asked to play video games for over 12 hours per day; Group #2 subjects were asked to play video games for no longer than 1 hour per day; and Group #3 subjects (control group) were not allowed to play video games at all. Phoria status was measured at the end of each session. The results showed that those in Group #1 on average had an esophoric posture after the gaming period; Group #2 subjects had an average exophoria of 2 prism diopters; and group #3 subjects averaged an exophoria of 6 prism diopters. The study suggested that excessive video game exposure leads to esophoria development.
What best describes the study type?
Experimental
Scenario: Based on anecdotal case reports in the literature, there is a suggestion that chronic vaping increases a person’s chances of developing a corneal ulcer.
Investigators decide to test this hypothesis via a prospective cohort study design. Which best describes the exposure and the outcome variables in the study?
Exposure = corneal ulcer, outcome = vaping
Scenario: Based on anecdotal case reports in the literature, there is a suggestion that chronic vaping increases a person’s chances of developing a corneal ulcer. Investigators decide to test this hypothesis via a prospective cohort study design.
How should the investigators first assemble the cohort groups?
They should first identify individuals by vaping use or non-use
Scenario: Based on anecdotal case reports in the literature, there is a suggestion that chronic vaping increases a person’s chances of developing a corneal ulcer. Investigators decide to test this hypothesis via a prospective cohort study design.
Which represents the most appropriate selection criteria for the cohort groups?
Exposed and unexposed groups should be about equal in age
Scenario: Based on anecdotal case reports in the literature, there is a suggestion that chronic vaping increases a person’s chances of developing a corneal ulcer. Investigators decide to test this hypothesis via a prospective cohort study design.
This study design NOT be able to address what?
This cohort study cannot investigate individuals with a corneal ulcer at the beginning of the study.
Scenario: In your private practice, you notice an increasing number of patients showing up with phlyctenulosis, an inflammatory opacification on the corneal-conjunctival junction. The patients’ histories vary by individual, with mentions of past positive tuberculosis skin tests, episodes of blepharoconjunctivitis, and past use of tetracycline antibiotics. You decide to investigate potential explanations for this apparent phlyctenulosis epidemic via a case-control study design, using your own patients as subjects.
What best describes any exposure and outcome variables in the study?
Exposure = tetracycline, outcome = phlyctenulosis
Scenario: In your private practice, you notice an increasing number of patients showing up with phlyctenulosis, an inflammatory opacification on the corneal-conjunctival junction. The patients’ histories vary by individual, with mentions of past positive tuberculosis skin tests, episodes of blepharoconjunctivitis, and past use of tetracycline antibiotics. You decide to investigate potential explanations for this apparent phlyctenulosis epidemic via a case-control study design, using your own patients as subjects.
How should study groups be identified for the case-control design?
First assemble a group of patients with phlyctenulosis and a matched group without phlyctenulosis
Scenario: In your private practice, you notice an increasing number of patients showing up with phlyctenulosis, an inflammatory opacification on the corneal-conjunctival junction. The patients’ histories vary by individual, with mentions of past positive tuberculosis skin tests, episodes of blepharoconjunctivitis, and past use of tetracycline antibiotics. You decide to investigate potential explanations for this apparent phlyctenulosis epidemic via a case-control study design, using your own patients as subjects.
Your preliminary study data suggest that those subjects with phlyctenulosis have a significantly higher past exposure history of a positive tuberculosis test than those without a positive test. What would best describe a confounding variable in this relationship?
A positive tuberculosis finding is the confounding variable
Scenario: In your private practice, you notice an increasing number of patients showing up with phlyctenulosis, an inflammatory opacification on the corneal-conjunctival junction. The patients’ histories vary by individual, with mentions of past positive tuberculosis skin tests, episodes of blepharoconjunctivitis, and past use of tetracycline antibiotics. You decide to investigate potential explanations for this apparent phlyctenulosis epidemic via a case-control study design, using your own patients as subjects.
What statements about this case-control study are true?
Selection of cases can result in bias, especially when selected from a specialty practice
The use of questionnaires makes case-control studies prone to recall bias from the subject’s end and interviewer bias from the investigator’s end
Cases and controls should be matched by age, gender, and presenting symptom
What best describes a cross-sectional study design?
Investigators examine subjects to determine intraocular pressure, and interview them about their current daily physical activity levels
A cross-sectional study finds a significant association between use of tobacco and glaucoma. Can causation be determined?
Tobacco use is correlated with glaucoma but causation cannot be determined
What is NOT true regarding cross-sectional studies?
A temporal cause and effect of exposure to outcome can usually be established
Which of the following should raise suspicion for selection bias?
a) Random sampling
b) A well defined target population
c) A consecutive sample of patients from one provider
d) Use of a database with each subject identified by a number
C
Which of the following is NOT likely to be generalizable to primary care optometric practice?
a) Anti-vegf study on retinopathy of prematurity
b) Effect of strict blood sugar control on diabetic retinopathy
c) Success of smoking cessation programs in dental offices
d) Corporate sponsored study on multifocal contact lenses for myopia control
A
Directional or differential misclassification occurs when:
Measures are higher than actual
T or F. Random misclassification does not bias results.
False
T or F. Regression to the mean is a statistical phenomenon only; it has no practical significance.
False
Which of the following is an example of confounding?
a) Convenience sample leads to non representative sample
b) Random assignment to groups does not lead to equal groups
c) The absence of a time element prevents conclusion as to cause and effect
d) Something differs between experimental and control groups which also affects outcome
D
What does the acronym DAG stand for?
Direct acyclic graph
T or F. A confounder can always cause the outcome by itself
False
T or F. The effect of a known confounder can often be controlled statistically
True
Describe the purpose and mission of public health (3)
1) The science & art of preventing disease, prolonging life, and promoting health through the organized efforts and informed choices of society, organizations, public and private communities, and individuals
2) Fulfilling society’s interest in assuring conditions in which people can be healthy.
3) Public health aims to provide maximum benefit for the largest number of people
Define key terms used in public health
1) Clinical Care
2) Determinant
3) Epidemic/Outbreak
4) Health Outcome
1) Think of Health Care!!
–>Prevention, treatment, and management of illness and the preservation of mental and physical well-being through the services offered by medical and allied health professions; also known as health care
2) Any factor whether event characteristic or other definable entity that brings a change in health condition or other defining characteristic.
3) A health event occurring more than normal.
–>Occurrence in a community or region of cases of an illness, specific health-related behavior, or other health-related event clearly in excess of normal expectancy. Both terms are used interchangeably; however, epidemic usually refers to a larger geographic distribution of illness or health-related events
4) Result of a medical condition that directly affects the length or quality of a person’s life
Public health aims to provide ___ with the right to be healthy and live in conditions that support health.
groups of people
A(n) ___ is a disease occurrence among a population that is in excess of what is expected for a given time & place.
Epidemic/Outbreak
Identify prominent events in the history of public health
- Sanitation and Environmental Health
1) 500 BCE
2) 1840s
3) 1970
What happened in 500 BCE?
Greeks and Romans practice community sanitation measures
What happened in 1840s?
The Public Health Act of 1848 was established in the United Kingdom
What happened in 1970?
The Environmental Protection Agency was founded
Identify prominent events in the history of public health
- Pandemics
1) Influenza
2) Polio
3) HIV
What happened with Influenza?
500 million infected worldwide in 1918
What happened with Polio?
Vaccine introduced in 1955; eradication initiative launched in 1988
What happened with HIV?
34 million living with HIV worldwide; 20% decline in new infections since 2001
Identify prominent events in the history of public health
- Prepared for Disaster Response
1) Biological Warfare
2) September 2001
3) Hurricane Katrina
What happened with Biological Warfare?
Plague used as a weapon of war during the Siege of Kaffa
What happened in September 2001?
Public health surveillance conducted after the 9/11 attacks
What happened in hurricane Katrina?
Emergency services, public health surveillance, and disease treatment provided
Identify prominent events in the history of public health
- Prevention Through Policy
1) Book of Leviticus
2) Tobacco Laws
3) Obesity
What happened with the Book of Leviticus?
The world’s first health code
What happened with the Tobacco Laws?
Banning smoking in public spaces
What happened with Obesity?
Food labeling and promotion of physical activity
Recognize the core public functions and services
Public Health Core Sciences [5]
1) Prevention Effectiveness
2) Epidemiology
3) Laboratory
4) Informatics
5) Surveillance
TF is cholera? [3]
1) Fatal intestinal disease
2) Death to ppl in London in 1800s
3) Thought to be transmitted by air, but actually travels through contaminated feces water
Who was John Snow? [2]
1) Father of MODERN epi
2) Traced source of cholera 1854
–> Tracked down cases with a map and if people drank water from a certain pump. He stopped the supply to the area.
Match –> a. Risk Factor identification/ b. surveillance / c. implementation/ d. intervention evaluation
1) What’s the problem?
2) What’s the cause?
3) What works?
4) How do you do it?
1) B
2) A
3) D
4) C
Recognize the core public functions and services
Three Core Functions of Public Health
1) Assessment
2) Policy Development
3) Assurance
What does assessment entail?
Systematically collect, analyze, and make available information on healthy communities on a federal, state and local level
Ex. Monitor tobacco use
What does policy development entail?
Promote the use of a scientific knowledge base in policy and decision making on a federal, state and local level
Ex. Increase tobacco tax
What does assurance entail?
Ensure provision of services to those in need on a federal, state and local level
Ex. resources to help smokers quit
What types of partners exist in the public health system? [7]
1) Community
2) Clinical Care System (Health Care)
–> Ex. Population & Individual patient focus
3) Gov. public health infrastructure
4) Employers and business
5) Academia ex. Harvard
6) The Media
7) Non-gov. organizations ex. American Cancer Society
Describe the role of different stakeholders in the field of public health
1) Media
2) Businesses & employers
3) Gov. Agencies
4) Academia
1) Public discourse, health education and promotion ex. social media
2) Provide health insurance, wellness initiatives & healthy workplaces
3) Health policies and city planning
4) Research, education, training and public service