Exam #1 Flashcards
perineum
- skin colored muscular area that covers the pelvic structres
- forms the base of the perineal body = a wedge-shaped mass that serves as an anchor for the muscles, fascia, and ligaments of the pelvis
squamocolumnar junction
- where two types of cells meet and is located inside the cervical os
- most common site for neoplastic changes
- site where cells are scraped for pap smear
ovulation
- the release of a mature ovum from the ovary at intervals, usually monthly
- two fxns of ovaries: ovulation and hormone production
- estrogen, progesterone and androgen are hormones produced by ovaries
breast self exam
- systemic palpation of breasts to detect signs of breast cancer or other changes
- best time to do it: 5-7 days after menstruations stops because physiologic alternaions in breast size and activity reach a minimum at this time
menarchy
- first menstruation
- marked increase of estrogen between 8-11 years of age
puberty
- broad term that denotes the entire transitional stage between childhood and sexual maturity
- increasing amounts and variations in gonadotropin and estrogen secretion develop into a cyclic pattern at least a year before menarche
- normally occurs in north america around age 13
- initially periods are irregular, unpredictable, painless and anovulatory
- after about a year of periods the hypothalmic pituitary rhythm develops and the ovary produces adequate cyclic estrogen to make a mature ovum
menstruation
- periodic uterine bleeding that begins approximately 14 days after ovulation
- controlled by a feedback system with 3 cycles: endometrial, hypothalmic-pituitary, ovarian
- avg length is 28 days, first day of bleeding is day 1 of cycle
- ## menses = day 1 of menstrual cycle, normally bleeding lasts 5 days with avg blood loss of 50mls
climacteric
- transitional phase during which ovarian fxn and hormone production decline
- this phase spans the years from the onset of of premenopausal ovarian decline to postmenopausal time when symptoms stop
menopause
- the last menstrual period
- can only be dated with certainty only 1 year after menstruation ceases
- avg age is 51.4 years, can be 35-60
perimenopause
- period preceding menopause that lasts about 4 years
- ovarian function declines
- ova slowly diminish and menstrual cycles may be anovulatory, resulting in irregular bleeding
- ovary stops producing estrogen and eventually menses no longer occur
sexual response cycle
- four phases: excitement, plateau, orgasmic, resolution
preconception care
- about 50% of all pregnancies in the US are unintended
- preconception care targets all women of reproductive age from menarche to menopausal transition
- critical fetal organ development between 17-56 days after fertilization. by the end of the 8th week and 1st trimester the major structural anomolaies in the fetus are already present
vulvar self exam
- VSE
- should be performed monthly between menses
- most lesions, malignancy, wart growth, and cysts can be felt and easily treated if diagnosed early
kegel exercises
- pelvic muscle exercises
- ## help with urinary incontinence
conception
- untion of single egg and sperm
- marks the beginning of pregnancy
- sequential process: gamete formation, ovulation, fertilizaion and implantation in uterus
mitosis
- body cels replicate to yield two cells with the same genetic makeup as the parent cell
- mitotic division facilitates growth and development or cell replacement
- each daughter cell receives one copy of the genetic material
meiosis
- germ cells divide and decrease their chromosomal number by half, produces gametes (sperm and eggs)
- each pair of chromosomes contains one chromosome received from the mother and one from the father, and results in cells that contain one of each of the 23 pairs of chromosomes
oogenesis
- process of egg formation, begins during getal life in the female
- all eggs are contained in a woman’s ovaries at birth
- 400-500 ovum mature during the 35 years of a woman’s productive life
zygote
- when sperm is united with egg
- ## at fertilization
spermatogenesis
- spermatocytes undergo meiosis
-
fertilization
- takes place in the ampulla (outer third) of the uterine tube
- when a sperm successfully penetrates the membrane surrounding the ovum, both sperm and ovum are enclosed within the membrane and the membrane becomes impenetrable to other sperm (zona reaction)
- cleavage: mitotic cellular replication begins as the zygote travels through the uterine tube into the uterus, takes 3-4 days
morula
- solid ball of cells produced within 3 days of fertilization
trophoblast
- gives rise to the placenta
embryonblast
- gives rise to the embryo
blastocyst
- whole structure of the developing embryo
- stem cells are derived from the inner cell mass of the blastocyst
implantation
- blastocyst embeds in the endometrium
- between 6-10 days after conception
- the trophoblast secretes enzymes that enable it to burrow into the endometrium until the entire blastocyst is covered
chorionic villi
- finger-like projections develop out of the trophoblast and extend into the blood-filled spaces of the endometrium
- vascular processes that obtain oxygen and nutrients from the maternal bloodstream and dispose of carbon dioxide and waste products into the maternal blood
decidua basalis
- the portion directly under the blastocyst that has embeded in the endometrium of the uterus
- decidua = implanted endometrium
embryo
- the stage of the embryo lasts from day 15 to 8 weeks after conception
- embryonic stage: most critical time in the development of the organ systems and the main external features
teratogens
- substances or exposure that causes abnormal development
chorion
- one of two fetal membranes that will surround the developing embryo
- develops from the trophoblast and contains the chorionic villi
- becomes the covering of the fetal side of the placenta
amnion
- one of two fetal membranes that will surround the developing embryo
- develops from the inner cells of the blastocyst
- the developing embryo draws the amnion around itself, forming a fluid-filled sac
amniotic fluid
- functions: helps maintain a constant body temperature, oral fluid, repository for waste ad assists in maintenance of fluid and electrolyte homeostasis, allows for movement, musculoskeletal development, cushions fetus from blunt trauma, acts as infection barrier, allows fetal lung development, facillitates symmetric growth
- fluid amt: at full term it should be 700-1000mls of transparent liquid
- contains: albumin, urea, uric acid, creatinine, lecithin, sphingomyselin, bilirubin, fructose, fat, leukocytes, proteins, epithelial cells, anzymes, lanugo hair
oligohydramnios
- less than 300ml amniotic fluid
- associated with fetal renal issues
hydramnios (polyhydramnios)
- more than 2 L of amniotic fluid
- associated with GI and other malformations
nuchal cord
- when the cord is wrapped around the fetal neck
placenta
- metabolic exchange
- by 20 weeks the placenta covers half the uterus
Functions: - endocrine gland function: produces 4 hormones = hCG (preserves corpus leutium so continuous supply of estrogen and progesterone can maintain pregnancy), hCS (stimulates maternal metabolism to supply nutrients for fetal growth), progesterone, estrogen
- metabolic functions: respiration, nutrition, excretion, storage. o2 and co2 diffuse back and forth through placenta membrane. carbs, proteins, calcium and iron are stored in placenta for ready access and water, inorganic salts, carbs, protens and fats and vitamins pass through maternal blood supply. fetus demans lots of glucose because of high metabolic rate, higher than mothers glucose levels. fetal waste crosses placental membrane and is excreted in mothers renal system
- maternal circulation: placenta depends on the maternal BP to supply circulation, 10% of mother’s cardiac output goes to fetus at term, vasoconstriction (HTN and cocaine) can decrease blood flow to uterus, decreased circulation can lead to intrauternine growth restriction of the fetus and small fetuses. best position for circulation is when woman is laying at rest on her side
fetus
- lasts from 9 weeks until pregnancy ends
viability
- capability of the fetus to survive outside the uterus and is usually defined by fetal weight and pregnancy duration
- 20 weeks, birth weight of 350g, 400g, or 500g
- infants who are 22-25 weeks of gestation are on the threshold of viability
ductus arteriosus
- special circulatory pathway by passes the lungs due to fetal lungs not funcitoning for gas exchange
- oxygen rich blood from the placenta flows rapidly through the umbilical vein into the fetal abdomen
ductus venosus
- vein goes into the inferior vena cava, it mixes with deoxygenated blood from fetal legs and abdomen
foramen ovale
- opening in left atrium
cephalocaudal
- blood flows first to heart, head, neck, and arms
- head to rump development of embryo/fetus
hematopoiesis
- the formation of blood
- occurs in the yolk sac, beginning in the 3rd week
- stem cells
- blood type is determined after the 6th week, so RH factor can become an issue then
surfactants
- the presence of surface active phospholipids in the amniotic fluid is used to determine the degree of fetal lung maturity or the ability of the lungs to function after birth
L/S ratio
- Lecithin: the most critical alveolar surfactant required for postnatal lung expansion. detectable at 21 weeks and increases in amt after week 24
- Sphingomyelin: remains constant in amount
- the L/S ratio: used to determine fetal lung maturity. 2:1 ratio the infant’s lungs are considered to be mature. occurs in the middle of the third trimester
- infants born c-section may have respiratory difficulty at birth due to the lack of squeezing through the birth canal. if fluid remains in the lungs, it will be absorbed into the infant’s bloodstream within 2 hours of birth
vernix caseosa
- white, cheesy material that protects the fetus’s skin
- thick at 24 weeks and scant by the time of birth
- cells of superficial layer mixed with sebaceous gland secretions
lanugo
- very fine hairs appear first at 12 weeks on eyebrows and upper lip
- by 20 weeks they cover the entire body
- by 28 weeks the scalp hair is longer than the lanugo
- lanugo may disappear by term gestation