Exam 1 Flashcards
1
Q
Name 3 important cytokines released during the inflammatory response.
A
IL-1
IL-6
TNF-a
2
Q
Which IL is responsible for effects on the hypothalamus and fever generation?
A
IL-1
3
Q
What are the two molecular structures of C3 convertase? Which pathways make which?
A
1) C4b2a (classical and lectin)
2) C3bBb (alternative)
4
Q
What happens if C3b binds to a host cell?
A
Factor H will inactivate it
5
Q
Importance of C5b?
A
initiates formation of membrane attack complex (MAC)
6
Q
Which IL stimulates naive cells to become Th1 cells
A
IL-12
7
Q
Which IL stimulates naive cells to become Th2 cells
A
IL-4
8
Q
Cytokines secreted by Th1 cells?
A
IL-2, TNF, INF-y
9
Q
Cytokines secreted by Th2 cells?
A
IL-4, IL-5, IL-10
