Exam 1 Flashcards
What is a bremsstrahulung X-ray?
A nucleus of an atom is bombarded with electrons. Usually tungsten.
This will account for the bulk of the X-ray photons produced.
What comprises the tube head?
Metal housing Powersupply(transformers X-ray tube Oil Collimater Aluminum filters Aiming cylinder (lead lined)
Describe high energy, medium energy, and low energy regarding bremsstrahlung radiation
High energy - Electrons directly collide with a nucleus, producing a high energy photon that is equal in energy to the incident electron.
Medium energy - electrons pass really close to the nucleus causing a sharp turn in the direction on the incident electron. This sharp turn will release energy in the form of a photon.
Low energy - same concept as the medium energy except the electrons pass at a distance, causing a wider turn and less energy released
Describe characteristic radiation.
An incident electron is projected at an atom. This electron strikes an electron in the inner shell and causes it to exit the atom. With a void in an inner shell, electrons fall back down to fill it up. In this process, energy is released.
It is important to note that the amount of energy is chracterisitc of the atom it involves. For example, tungsten is 59eV
This accounts for only a small amount of the X-ray photons generated.
Describe the cathode and anode in an X-ray tube.
Cathode: - a tungsten filament and molybdenum focusing cup provide the source and direction of electrons of the cathode ray. Low voltage is used to heat the filament, producing a cloud of electrons through thermionic emission. The molybdenum focusing cup focuses the electrons into a narrow beam.
True or false… light, heat, sound, and microwaves are all examples of radiation
True
Define radiation. What is the difference between ionizing and nonionizing radiation?
Radiation is the transmission of energy through space and matter.
The difference between ionizing or non-ionizing radiation is its ability to knock out electrons, thus breaking bonds. Ionizing is able to do so and has a lot more energy. Ionizing radiation produces molecular chemical change and can lead to cell death and other harmful effects
About what percent of radiation comes from natural sources?
50%
The other 50% is man mad sources
What is the greatest source of natural radiation?
Radon (37% of total radiation exposure)
Cosmic 5%
Terrestrial 3%
Internal 5%
What is the greatest source of man made radiation?
CT scans (24% of total radiation) Medical X-rays (12%)
What is the difference between particulate radiation and electromagnetic radiation? Name some examples of each
Particulate radiation typically associated with a lot more energy. Involves particles. (Alpha particles, beta particles, neutrons). Electromagnetic radiation involves photons (gamma rays, X rays)
Which of the following is not a form of ionizing radiation? Why? X-rays Microwaves Gamma rays UV light
Microwaves, because these have lower energy than visible light. The other types of radiation have more energy than visible light, thus are ionizing
What is dosimetery?
How radiation is measured
What are the SI units for the following? Exposure Absorbed dose Equivalent dose Effective dose Radioactivity
Coulomb/kilogram
Gray (Gy)
Sievert (Sv)
Sievert. (Sv)
Becquerel (Bq).
What does the measurement of radioactivity measure?
Decay rate of a radioactive material.
What does exposure measure?
Exposure is. A measure of radioactive kinetic. Energy emitted from a source and is quantified by its capacity to ionize air. It is a measure of the intensity of the radiation field. It is expressed in units of charge per mass
What is absorbed dose?
The absorbed dose is the energy absorbed by any type of matter, and is derived by calculating the imparted energy divided by the mass absorbing it. Measured in Grays.
Some of the energy absorbed will make changes, some doesn’t affect anything. Absorbed dose simply measures how much is absorbed
What is equivalent dose?
The equivalent dose is used to compare the biological effect on a tissue from different types of radiation.
Dependent on linear energy transfer, which varies depending on the type of radioactive therapy.
Particulate radiation has higher LET than photons, thus a greater biologic effect.
Describe linear energy transfer
Particulate radiation > photons.
think of particulate radiation like a large marble hitting a smaller one. Lots of potential energy is transferred. Photons, however is like sand hitting a marble, it doesn’t really do much
What is effective dose?
Effective dose is used to measure the estimated risk to humans
This takes into account the type of radiation (equivalent dose) and the nature of each organ or tissue being irradiated, then sums it up to get a whole body effective dose.
List in order from most to least, the following tissue/organs by how susceptible they are to radiation damage.. brain, breast, skin, thyroid, gonads
Breast, gonads, thyroid, skin, brain
More rapidly dividing, less differentiated cells are most susceptible
The reason we may wish to cover the reproductive organs of a patient when taking radiographs can be explained by the concept of ___
Effective dose
In regards to radiobiology, what is the direct effect? What are some of its free radical fates?
When a photon or secondary electron ionizes biological macromolecules.
The free radical can then break down into two smaller molecules (dissociation), or it can undergo cross-linking meaning that it can join with other free radicals to form new molecules
Accounts for 1/3 of biologic damage from X-rays
Radiolysis of water occurs when a photon is absorbed by water in an organism, ionizing water molecules into free radicals. The products formed from this could be…
H* and OH*
In the presence of dissolved O2…
HO2*
H2O2
What is the indirect effect?
Free radicals and toxins produced through the intermediate step of water radiolysis interact with biologic macromolecules to cause changes.
involves radiolysis of water as a precursor to biologic damage. It accounts for 2/3 of biologic damage from X-rays
What is the primary cause of radiation induced cell death?
Damage to DNA
Damage to DNA results from… (4 things)
Breakage of one or both DNA strands
Cross-linking of DNA strands within helix to other DNA strands
Change or loss of base
Disruption of hydrogen bonds between DNA strands
True or false… H2O2 contributes to the indirect effect of ionizing radiation on altering DNA?
False
Once H2O2 is produced, it doesn’t affect DNA
What is the deterministic effect?
Radiation injury dependent on the dose (the greater the dose the greater the severity)
What are some long-term effects of irradiation (months and years after exposure)
Loss of parenchyma cells and replacement with fibrous connective tissue
Loss of capillaries with impairment of oxygen transport, nutrient transfer, waste removal
What are some modifying factors of the deterministic effect on tissues?
Dose - above threshold level damage is proportional to dose (yes there is a threshold for deterministic effect)
Dose rate
Oxygen - damage increases as oxygen increases
LET
Is radiation more or likely to affect cells that are highly differentiated or undifferentiated?
Undifferentiated
What are the clinical manifestations of the following doses? 1-2 Gy 2-4 Gy 4-7Gy 7-15 Gy 50 Gy
1-2: prodromal symptoms 2-4: mild hematopoietic symptoms 4-7: severe hematopoietic symptoms 7-15: gastrointestinal symptoms 50: cardiovascular and CNS symptoms
What is the stochastic effect?
Radiation injury is based on the probability of occurrence (All or none phenomenon). The probability of the effect occurring increases with dose. there is NO threshold level.
The occurrence of radiation induced cancer and genetic alterations are stochastic effects, resulting from sublethal damage to dna
What are the three guiding principles to radiation safety?
Justification
ALARA
Dose limitation
What does ALARA stand for?
We should keep radiation exposures As low as reasonably achievable for adequate diagnosis and evaluation
What justification mean in regards to radiation safety?
The dentist has the obligation to do more good than harm. In selecting radiographs, the benefit to the patient from diagnostic exposure should exceed the low risk of harm
True or false… there are set dose limitations in diagnostic and therapeutic radiology
False. However the dentist should limit the amount of exposure as much a as possible by adhering to good radiation safety practices and have a radiation protection program in place.
True or false.. dentists should not prescribe routine dental radiograps at preset intervals for all patients
True. Rather, they should prescribe radiographs after an evaluation of the patients needs that includes… a health history review, a clinical dental history assessment, a clinical examination, and an evaluation of susceptibility to dental diseases