Exam 1: Brain Development Flashcards
EEG
electrical recordings on scalp
generated by neurons
Used to study the time course of neural events and brain/behavior relationships.
Event related potentials (ERP) detect changes in brain’s electrical activity that occur in response to a particular stimulus.
MEG
detects magnetic fields generated by electrical currents in the brain
-unlike eeg, MEG can localize the origin of electrical signals in brain and their time course
fMRI
detect fluctuations in cerebral blood flow in different areas of the brain
MRI
snapshot of brain
When does neurogenesis begin?
42 days after conception
Arborization
increase in size and complexity of dendrites
-form spines
-inc ability to connect with other neurons
White matter vs grey matter
White matter: myelinated axons
Grey Matter: cell bodies at surface of cortex
Last area of cortex to mature
Dorsolateral prefrontal cortex
-regulates attention, controlling impulses, foreseeing consequences, setting priorities, executive functions
Autism Spectrum Disorder
atypical pattern of pruning: delayed or reduced rate of synaptic pruning
-larger brains, greater synaptic densities, increased cortical thickness
Schizophrenia
Atypical pattern of pruning: excessive pruning in adolescence
Timing and onset of schizophrenia in adolescence linked to aberrant pruning around puberty
Experience-Expectant Plasticity
Each species evolves in specific niche with predictable array of experiences available to all typically developing members of that species.
evolutionary Experiences -> how brain development unfolds
ex. pattern visual, voices, movement -> human brain expects this input
Happens during sensitive periods. Subject to synaptic pruning (use it or lose it).
Intrinsically and extrinsically regulated
Experience-dependent plasticity
neural connections are created and reorganized throughout life gaining experiences
extrinsically regulated
Worst time to suffer brain damage
when neurogenesis and neuron migration occur (prenatal development all way through 1st year after birth)
When is greatest plasticity observed
synapse generation and pruning during early childhood
Near-infared spectroscopy (NIRS)
measures neural activity via metabolic change
-good for infants and young children