Exam #2 Flashcards

1
Q

Multiple Alleles

A

presence of two or more alleles at a locus group.

ex- bloodgroup system

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2
Q

Antigen

A

any substance that can induce the production of an antibody

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3
Q

gene interaction

A
  • occurs when genes at two or more loci work together to determine a single phenotype.
  • one phenotype can be controlled by alleles of two different genes.
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4
Q

Epistasis

A
  • special form of gene interaction

- the genotype at one locus masks the expression of the genotype at a second locus

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5
Q

types of epistasis

A

recessive, dominant, duplicate recessive, duplicate dominant, duplicate interaction, dominant and recessive, and none.

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6
Q

epistatic gene

A

gene doing the masking

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7
Q

hypostatic gene

A

gene being masked

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8
Q

recessive epistasis

A

there is a recessive allele but when it has a pair making it homozygous recessive, it doesn’t matter what the other pair is, this one will mask the other allele. it does have to be the specific allele of the pair at the loci.
9-3-4

ex- coat color in labs, or O blood type

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9
Q

dominant epistasis

A

only a single copy of the allele is needed to mask the other allele.
12-3-1

ex- squash color

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10
Q

duplicate recessive epistasis

A

if you have a pair of homozygous alleles it masks the other. It doesn’t have to be a specific one. it can be a or b.
9-7

ex-snails

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11
Q

duplicate dominant epistasis

A

15-1
dominant allele masks all the recessive alleles. At either loci.

the one comes from both aabb alleles.

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12
Q

sex influenced

A
displayed differently in each sex
ex-beards in goats=
heterozygote male= beard
heterozygote female=no beard
AUTOSOMAL GENES
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13
Q

sex limited

A

only occurs in one sex.

AUTOSOMAL

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14
Q

conditional alleles

A

show an extreme influence of environment on phenotype

ex-PKU and diet

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15
Q

conditional mutant

A

only expressed at certain environmental conditions
ex- wild type @low temp
mutant @high temp

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16
Q

discontinuous traits

A

exhibit only a few easily distinguished phenotypes
-qualitative
ex- seed shape= either round or wrinkled

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17
Q

continuous traits

A

displays a large number of possible phenotypes that are not easily distinguished.
-quantitative
ex- human height

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18
Q

pleitropy

A

single allele associated with multiple phnotypes

19
Q

phenocopy

A

produced by environmental effects that is the same as the phenotype produced by a genotype

20
Q

polygenic traits

A

a bunch of genes influencing a single trait

21
Q

Morgan and his student alfred sturvant established

A
  • genes linked to chromosomes
  • linked genes do not assort independently
  • the closer two genes are the more often they are transmitted together.
  • degree of co-transmission (linkage) can be used to construct genetic maps.
22
Q

sources of recombination of genes

A
  • independent assortment- genes of separate chromosomes.

- crossing over-genes lying on the same chromosome

23
Q

complete linkage

A

only non recombinant progeny produced

24
Q

independent assortment

A

half the progeny are recombinant and half are not

25
Q

genetic map units

A

centiMorgan=cM or map unit=mu

one cM=1% recombinant progeny types

26
Q

Genome wide association studies (GWA)

A

looks for associations between genes and molecular markers with in populations

27
Q

SNPs

A

Single Nucleotide Polymorphism
mapping markers
millions on the human genome

28
Q

haplotype

A

set of particular alleles inherited as a group

29
Q

multifactorial characteristics

A

Characteristic determined by multiple genes and environmental factors.

30
Q

compound heterozygote

A

two different defective recessive alleles in the heterozygote. which makes it express itself.

31
Q

alleleic mutations(at same loci)

A

only mutant alleles

32
Q

non allelic mutations (Different loci)

A

wildtype

33
Q

complimentation

A

+

34
Q

not compliemnation

A

-

35
Q

complementation

A

not on same gene

36
Q

cis

A

coupled genes

37
Q

rate of recombination

A

2x more in women

38
Q

linkage disequalibrium

A

nonrandom association between alleles and a haplotype

39
Q

snps

A

general area

40
Q

fish

A

know exact ocaition

only finds specific gene not base pairs

41
Q

GWA

A

general area

42
Q

observed

A

underestimates actual map distance

43
Q

genetic imprinting

A

only express genes from mother or father

imprinted mamaleian genes influence fetal growth

44
Q

two point test cross

A

exmines inheritance of two linked genes