Exam 3 Flashcards
gene regulatory networks
biological circuits that respond to signals by activating genes during development, metabolisms and cell cycle, made up of interacting genes, transcription factors, promoters and RNA, allows for evolution of complexity by being expressed at different times or in different tissues
gene duplication
can produce novel functions because one copy stays pristine due to purifying selection and duplicate can evolve new regulation and function
Promiscuous protein
capable of carrying out two functions;
are especially likely to take on new functions if duplicated
Gene recruitment
the co-option of a particular gene or
network for a totally different function as a result of a
mutation; the reorganization of a preexisting regulatory
network can be a major evolutionary event
evolution by natural selection
individuals vary in some traits, some of the differences in traits are passed along to offspring through genes (must be heritable), different individuals produce different numbers of surviving offspring, the particular value of a trait is connected to the number of offspring produced (trait is connected to fitness)- Traits that allow for more offspring to be produced are said
to be “naturally selected”
asexual individuals
should outcompete sexual individuals but exclusive asexuality is uncommon
sex
combination and mixing of chromosomes, involves meiosis and fertilization (horizontal gene transfer is not)
costs of sex
only females reproduce directly in 2 sex species, breaks down good gene combinations, meiosis takes longer than mitosis, if population density is low its more difficult to reproduce (search for partner), male-female cuts list of potential mates in half (indiscriminate sex does not exist), STDs, reduced relatedness to offspring than asexual reproduction
benefits of sex
removes bad mutations and combines good ones through recombination that generates individuals with allele combos that exclude deleterious mutations-Mullet’s ratchet, increased genetic diversity leads to novelty and increase resistance to parasites (tangled bank hypothesis, red queen hypothesis)
Mullet’s ratchet in asexuals
removing bad mutations and recombination of genes not possible in asexual, therefore greater fitness in sexual lines
tangled bank hypothesis
sex allows for organisms to take advantage of diverse environments aka more adaptability
red queen hypothesis
increased resistance to parasites, one step ahead of parasite coevolution of two
gametic anisogamy- organelles theory
reproductive cells are of different sizes (males- small, abundant, motile; females- larger, fewer, non-motile), if both were same size and had sets of organelles, which organelles would be adopted would be a problem
sex determination
mammalian model- not deterministic, lots of things need to be turned on, conversation between genes (genetic sex-> gonadal sex-> phenotypic sex), chicken model- sex chromosomes are associated with somatic cells (can get gynandromorphs) (soma->phenotype) but in mammals we don’t carry sex identity in our soma (start with undifferentiated model)
intersexual selection
Members of the same sex compete for access to mates, often leads to the evolution of weapons and/or large body size