EXAM 4: NEOPLASIA OF THE NERVOUS SYTEM

Question 1

What is the most common type of primary intra-axial CNS neoplasia in dogs and cats?

Answer 1

Neoplasia of glial cell origin (glioma)

Question 2

What are the 2 major types of primary intra-axial neoplasia of the CNS?

Answer 2

Astrocytoma
Oligodendroglioma

Question 3

Gross Appearance: Astrocytoma

Answer 3

Firm and tan-gray with indistinct boundaries

Question 4

Gross Appearance: Oligodendroglioma

Answer 4

Gelatinous or mucoid texture

Question 5

Where are chorioid plexus tumors commonly found? What do they result in?

Answer 5

Ventricular location
Hydrocephalus = obstructive or increased CSF production

Question 6

Where are ependymomas commonly found? What do they result in?

Answer 6

Ventricular system (lateral and 3rd most common)
Obstructive (acquired) hydrocephalus

Question 7

What is the most common primary CNS tumor of dogs and cats?

Answer 7

Meningioma

Question 8

Where are thoracolumbar spinal cord tumors of young dogs (spinal nephroblastoma) found? Signalment?

Answer 8

Between T10-L2
Young (<1yr) large breed dogs

Question 9

What is the common leukocytic tumor found in cattle?

Answer 9

Bovine leukemia virus-associated (intradural and extramedullary - cauda equina)

Question 10

What tumor-like lesion can be found in older horses and is usually incidental?

Answer 10

Cholesteatoma (cholesterol granuloma)

Question 11

What are the 2 mechanisms of spread of secondary tumors of the CNS?

Answer 11

Direct extension
Hematogenous metastasis