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SA-BIOCHEMII > EXAM1 > Flashcards

EXAM1 Flashcards

1
Q

An enzyme used in both GLYCOLYSIS and GLUCONEOGENESIS

A

Phosphohexoisomerase

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2
Q

ATP can be hydrolysis by several ways. In presence of COOH which pairs of reaction the ATP provide MOST ENERGY

A

R-COOH + ATP + R-po2-adenine+ PPi

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3
Q

How does Arsenate effect glycolysis

A

Lead to net production of NO ATP

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4
Q

The main function of pentose phosphate pathway is to

A

Supply Pentose and NADPH

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5
Q

Which are an effect of Ephernephine

A
  • It activates GLYCOGEN PHOSHORELASE

- Blocks activation of glycogen synthase

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6
Q

Indicate the appropriate intermediate in the catabolism of lactose by completing the following sentence

A

Lactose is first broken into componenet monomers of these is glucose. the other is [GALACTOSE] , can be catabolised through multi step process to form [GLUCOSE-6-PHOSPHATE], an intermediate of glycolysis

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7
Q

Last step of glycolysis involves conversion of phosphenol pyrute to pyrute synthetic glucose. Most organisms accomplish this

A

The reaction has a net requirement of (2) ATP equivalent PER Pyruvate

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8
Q

Assume Lactate is not available. How is NADH involved in reversal

A

1 Mole is consumed in Mitochondria and Formed in Cytosol for each mole of Pyruvate consumed

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9
Q

How many ATP equivalent and molecule of NADH are directly required for the synthesis of one molecule of glucose

A

(6) ATP, (2) NADH

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10
Q

Which of the following pairs of reactions is futile cycle

A
  • Pyruvatic + ATP + Phosphenolpyruvate

- Phosphenolpyruvate + H2O pyruvate + PPi

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11
Q

Which of the following is true about this pair of reactions (fructose 6 phosphate + ATP –> fructose 1,6 phosphate +ADP)

A

AMP promote reaction #1 and inhibit reaction #2

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12
Q

Which is the following is true about regulation of HEXOKINASE

A

Both 2 & 3 in muscle tissue is regulated by Feedback Inhibition
3- In Liver tissue is regulated primarly by Glucose Concentration

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13
Q

There is resciprocal regulation of glycolytic and glucogenic reaction interconverting fructose-6-phosphate and fructose 1-6 biphosphate. What about this regulation is NOT correct

A

Phosphofructokinase is Endergonic

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14
Q

Pyruvate can either undergo series of catabolic reactions yield energy or transform into glucose (glucogensis). Primary way of regulation how pyruvate is metabolized

A

Acetyl CoA promotes glucogenesis and Inhibits the catabolism of pyruvate

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15
Q

Which of the following will low blood glucose promote

A

Activation of FBPease and inactivation of Pfk-1

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16
Q

The primary immediate product of glycogen break down is _____. Immediate substrate of glycogen is____

A

breakdown: Glucose-1-Phosphate
substrate: UDP Glucose

17
Q

Which statement is true about regulation of pyruvate kinease

A

Both:

  • An elevated ATP inhibits PK
  • An Elevated Glucagon lead to inactivation of PK
18
Q

Glycogen

A

Primer on which New Glycogen chains are initiated

19
Q

Enzime PP1 catalyzes the inactivation of glycogen phosphorylase and activation of glycogen synthase. Which inhibits to PPI

A

Epinephrine and Glucagon

20
Q

Which of the following decrease glycogen phosphorylase activity

A

Insulin

21
Q

Which of the following sweeteners does not provide energy

A

Acesulfame-K

22
Q

Which of following sweeteners is not FDA approved?

A

Cyclamat

23
Q

When atient has Phenyketouria, which is a problem

A

Aspartame

24
Q

On box of cheerios, fiber is 5g. What is % of DV

A

20%

25
Q

Which of the following is NOT TRUE regarding insoluble fibers

A

Lowers the cholesterol blood level

26
Q

Which of the following is TRUE regarding soluble fibers

A

They are digested by bacteria in the intestine

27
Q

Which of the following is NOT TRUE regarding GSK3

A

Its stimulated by epinephrine and causes phosphorylation, THUS activation of glycogen synthase

28
Q

Which of the following is TRUE regarding glycogen synthase?

A

Its inhibited by by epinephrine and causes dephosphorylation of the enzyme

29
Q

What are the dietary recommendations of CHO in 2000Kcal

A

45-65%

SA-BIOCHEMII (3 decks)

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