Exam2 Flashcards
Hyperlipidemia
Refers to chronic elevations in fasting blood concentrations of triglycerides, cholesterol or specific Sub-fraction of each
Dyslipidemia
A combination of genetic, environmental and pathological factors that can work together to abnormally alter blood lipid and lipoprotein concentrations
Metabolic syndrome
Signs and symptoms
Elevated glucose Hypertension Elevated triglycerides Low high-density lipoprotein cholesterol level Abnormal obesity Microalbuminuria Hyperuricemia Fatty liver disease
Metabolic syndrome
Risk factors
Elevated waist circumference Elevated triglycerides Reduced HDL cholesterol Elevated blood pressure Elevated fasting glucose
Exercise prescription for dyslipidemia
Cardio: 150-300 weekly minutes of moderate intensity or 75-150 of vigorous
Muscle strength: 8-10 exercise with 8-15 reps per exercise
Acute coronary syndromes (ACS)
Include
Unstable angina pectoris
Acute myocardial infarction
Potentially Sudden cardiac death
Unstable angina
Transient vessel occlusion<10 min
Myocardial infarction
Vessel occlusion >60 min, resulting in necrosis of myocardial tissue
Primary cause for atherosclerosis
Obesity Tobacco use Dyslipidemia Hypertension Sedentary lifestyle Diabetes mellitus
Pathophysiology (atherogenesis)
Endothelial injury Inflammation response Platelet aggregation, growth factor and vasoconstriction Monocytes accumulation LDL-C accumulation and oxidation
Atherosclerosis
An active process involving molecular signals that produce altered cellular behaviors as well as endothelial dysfunction and subsequent inflammatory response and lipid deposition
Physical examination considerations for ACS
Systolic hypertension Diaphoresis Sinus tachycardia Tachypnea New murmur of mitral regurgitation Third and forth heart sounds Pulmonary tales
Electrocardiogram
Chest radiograph
Laboratory results
Diagnosis of acute myocardial infarction
Chest pain persisting >40mins
ECG showing ST- segment or T- wave changes
Presence of biomarkers of myocyte necrosis
Classification of myocardial infarction
ST- segment elevation
Non-ST-segment elevation
ACS exercise prescription
Frequency: 4-7 days a week
Consider multiple sessions daily if low exercise capacity
Intensity: RPE 11-16
40-80% HRR
+20 beats/min below ischemic threshold
Duration: starting with 5-10 min
Goal=20-60 min
Gradual increase of 1-5 min per session
Type: aerobic: large muscle groups
Indoor and outdoor options