EXAM3 Flashcards
What will happen to the rate of oxygen consmption
It will decrease
Most of NADH in a cell is produced in the mitochondria matrix and some is produced in the cytosol. Which of the following is NOT TRUE about this cytosolic NADH:
In the heart it is carried into the matrix by the cardiac NADH transporter complex
In normal mitochondria the rate of NADH consumption (OXIDATION) will be:
a) increase in active muscle and decreased in inactive muscle.
b) very low if the ATP synthase is inhibited but increase if uncoupler is add.
c) decrease if mitochondria ATPase is depleted
d) decrease when cyanide is used to prevent electrons transfer through the cytochrome A
[ALL OF THE ABOVE]
Rate of oxidative circulation in mitochondria is controlled primarily by:
The mass action ratio of the ATP-ADP system
With regard to oxidative phosphorelation:
RETENONE inhibits the removal of electrons through complex I, while THERMOGENINE is an uncoupling agent
For the synthesis of one mole of archidic acid, (C20) how many moles of NADPH are required
18
Cytosolic NADPH is produced by
Endo-phosphate pathway and the oxidative of pyruvate to malate
Which of the following are true:
COX 1 catalyzes a reaction that lead to the synthesis of thromboxane, produce platelet aggregation
Fill in the three blanks: ___ are the primary transporter of cholesterol and cholestryl esters from extra-hepatic tissues to the liver, and ___ transport dietary lipids from the intestine to other tissues, and ___ transport cholesterol to various tissues
HDL, Cholymicrones, LDL
Which of the following does an elevated intracellular concentration of cholestrol increase:
Synthesis of cholestryl esters
Which is not true about allopurinol
Prevents the formation of excess urea
Synthesis of nucleotide and deoxynucleotide
GDP—dGDP
What is true about adenlyl synthase
Uridenylyl to active glutamine synthase
Which is not true
MAO inhibits breakdown of serotonin
Epinephrine
inhibit FA mobilization
promote gluconeogenisis
