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MSSK > export_path practice test 2 > Flashcards

export_path practice test 2 Flashcards

1
Q

A 58-year old man comes to the physician because of an ulcer on his lower lip . The lesion has been there about 6 months, but lately it has been very “crusty ”. It started bleeding last week, and his wife scheduled this appointment. Physical examination shows a 1.3 cm hyperkeratotic and eroded plaque on his lower lip. Microscopic evaluation will most likely show which of the following?

   A) Basaloid epidermal hyperplasia and keratin-filled epidermal pseudocysts 

   B) Epidermal hyperplasia, elongation of rete ridges, and Munro microabcesses 

   C) Invasive nests of basaloid cells with palisading growth pattern 

  D) Nests of atypical keritonocytes, keratin pearls, and intercellular bridges

   E) Pautrier microabcesses and superficial dermal infiltrate of T lymphocytes
A

D) Nests of atypical keritonocytes, keratin pearls, and intercellular bridges

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2
Q

A 5-year-old boy has honey-colored crusted lesions on his upper lip and cheek . His temperature is 37.2 degrees C. The first lesion was believed to have started in a scratch . The most likely diagnosis is

   (A) psoriasis  

   (B) contact dermatitis  

  (C) impetigo 

   (D) pityriasis rosea
A 
   (C) impetigo
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3
Q

A 43-year-old man presents with scaly lesions involving his right elbow and both knees . Six months ago he first developed brown papules on the skin of both knees , followed by scaling . An uncle has had a similar skin problem for 10 years . The most likely diagnosis is

   (A) lichen planus  

   (B) lichen sclerosis et atrophicus  

     (C) lupus erythematosus  

   (D) seborrheic dermatitis  

  (E) psoriasis
A 
   (E) psoriasis
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4
Q

A 26-year-old woman presents with a 2 month history of tender red nodules confined to her shins . The referring physician suspects that the lesions are drug induced . The most likely diagnosis is:

   (A) urticaria  

  (B) erythema nodosum 

   (C) atopic dermatitis  

   (D) herpes simplex
A 
   (B) erythema nodosum
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5
Q

Immunofluorescence techniques demonstrate antibody localized to the intercellular areas of the stratified squamous epithelium in

   (A) lichen planus  

  (B) pemphigus vulgaris 

   (C) bullous pemphigoid  

   (D) lupus erythematosus
A 
   (B) pemphigus vulgaris
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6
Q

Edema and subepithelial vesicles may be seen in

     (A) dermatitis herpetiformis 

   (B) bullous pemphigoid  

  (C) both     

   (D) neither
A

c. both

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7
Q

A subepidermal bulla is seen in

  (A) bullous pemphigoid 

   (B) pemphigus vulgaris  

   (C) both  

   (D) neither
A 
   (A) bullous pemphigoid
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8
Q

Vesicular lesions of the epidermis are characteristic of all of the following EXCEPT

   (A) Darier's disease  

   (B) smallpox  

   (C) herpes simplex  

   (D) pemphigus  

  (E) molluscum contagiosum
A 
   (E) molluscum contagiosum
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9
Q

Munro’s microabscesses are a feature of

   (A) superficial melanoma  

   (B) pemphigus  

  (C) psoriasis 

   (D) impetigo  

   (E) dermatitis herpetiformis
A 
   (C) psoriasis
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10
Q

Acantholysis is a prominent histologic feature in

   (A) keratoacanthoma  

   (B) seborrheic keratosis  

   (C) acne vulgaris  

  (D) pemphigus vulgaris
A 
   (D) pemphigus vulgaris
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11
Q

Hyperkeratosis without parakeratosis is associated with

  (A) lichen planus 

   (B) psoriasis  

   (C) both  

   (D) neither
A 
   (A) lichen planus
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12
Q

Of the following features, which is common to both pemphigus vulgaris and bullous pemphigoid ?

   (A) acantholysis  

   (B) formation of subepidermal bullae  

   (C) invariable involvement of buccal mucosa  

   (D) relentless progression of disease  

  (E) probable autoimmune pathogenesis
A 
   (E) probable autoimmune pathogenesis
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13
Q

Which one of the following conditions typically demonstrates intraepidermal (suprabasal) vesicles histologically?

   (A) second degree burn  

   (B) dermatitis herpetiformis  

   (C) bullous pemphigoid  

   (D) porphyria cutanea tarda  

  (E) pemphigus vulgaris
A 
   (E) pemphigus vulgaris
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14
Q

The predominant cell type involved in urticaria (hives) pigmentosa is

   (A) B lymphocyte  

   (B) eosinophil  

   (C) Langerhan's cell  

  (D) mast cell 

   (E) T lymphocyte
A 
   (D) mast cell
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15
Q

Acne vulgaris is related to

   (A) stimulation of apocrine glands at the time of puberty  

     (B) distention and inflammation of sebaceous follicles 

   (C) both  

   (D) neither
A

(B) distention and inflammation of sebaceous follicles

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16
Q

Impetigo is occasionally causally related to

   (A) acute rheumatic fever  

   (B) rhematoid arthritis  

  (C) glomerulonephritis 

   (D) erythema multiforme  

   (E) exfoliative dermatitis
A 
   (C) glomerulonephritis
17
Q

The earliest lesion of acne is a

   (A) cyst  

  (B) comedone 

   (C) pustule  

   (D) scar  

   (E) vesicle
A 
   (B) comedone
18
Q

A rapidly spreading erythematous eruption with raised margins is most likely to occur in a patient with

   (A) mycosis fungoides  

   (B) systemic lupus erythematosus  

   (C) rheumatic fever    

   (D) xeroderma pigmentosum  

     (E) diabetes mellitus
A 
    (C) rheumatic fever
19
Q

The Fite stain is used to diagnose

   (A) chancroid  

   (B) histoplasmosis  

  (C) leprosy 

   (D) lupus vulgaris  

   (E) meningococcemia
A 
   (C) leprosy
20
Q

A viral infection of the skin with multinucleated cells containing intranuclear inclusions is

     (A) molluscum contagiosum  

   (B) verruca vulgaris  

  (C) herpes simplex 

     (D) verruca plantaris  

   (E) seborrheic keratosis
A 
   (C) herpes simplex
21
Q

The most typical location of a paronychia is

   (A) back of neck  

  (B) fingernail 

   (C) rostral to anus  

   (D) face  

   (E) trunk
A 
   (B) fingernail
22
Q

Potassium hydroxide preparation of a scraping of a slightly scaly lesion from the upper back reveals spores and hyphal forms along with squamous cells but no inflammatory cells . The most likely

Fungus is

   (A) candida albicans  

   (B) trichophyton tonsurans  

     (C) epidermophyton floceosum  

  (D) malassezia furfur 

     (E) microsporum audouinni
A 
   (D) malassezia furfur
23
Q

Acne vulgaris is best thought of as a

  (A) folliculitis 

   (B) keratosis  

   (C) eczema  

   (D) panniculitis  

   (E) cellulitis
A 
   (A) folliculitis
24
Q

Which of the following is significant in the pathogenesis of acne vulgaris ?

    (A) comedone formation 

   (B) perforation of a sebaceous follicle with resulting perifolliculitis  

  (C) both     

   (D) neither
A

c. both

25
Q

A Tzanck smear is done on a skin vesicle to obtain a cytologic evaluation of the cells in the vesicle. Multinucleated cells are seen as well as cells with nuclear inclusions. The most likely diagnosis is

   (A) benign familial pemphigus  

   (B) Stevens-Johnson syndrome  

  (C) herpes simplex infection 

   (D) pemphigus vulgaris  

   (E) acute allergic contact dermatitis
A 
   (C) herpes simplex infection
26
Q

In psoriasis , the epidermis may contain

    (A) nuclei in the stratum corneum 

   (B) microabscesses  

  (C) both     

   (D) neither
A
  • c. both
27
Q

Liquefaction degeneration of the basal epidermal layer is characteristically seen in

   (A) Bowen's disease  

  (B) lupus erythematosus 

   (C) psoriasis  

   (D) seborrheic keratosis
A 
   (B) lupus erythematosus
28
Q

Lichen planus is characterized by each of the following EXCEPT

   (A) pruritis  

   (B) violaceous papules  

   (C) hyperkeratosis  

  (D) epidermal microabscesses 

   (E) dense subepidermal lymphoid infiltrate
A 
   (D) epidermal microabscesses
29
Q

The histologic features of psoriasis include each of the following EXCEPT

   (A) parakeratosis  

   (B) acanthosis  

   (C) thinned suprapapillary epidermis  

   (D) microabscesses  

  (E) acantholysis
A 
   (E) acantholysis
30
Q

A section of skin shows prominent keratin plugs , moderately atrophic epidermis , degeneration of the basal layer and pigment in the upper dermis . This is most likely

  (A) discoid lupus 

   (B) erythema multiforme  

   (C) lichen planus  

     (D) solar keratosis  

   (E) stasis dermatitis
A 
   (A) discoid lupus
31
Q

The primary lesion in lichen planus is

   (A) dermal infiltration which causes rupture and splitting of the basal lamina  

   (B) the development of colloid bodies in the lower most epidermis or upper dermis  

     (C) liquifactive degeneration of the basal cell layer 

   (D) deposition of fibrin in the upper dermis  

   (E) reduced mitotic activity and cell proliferation in the basal layer
A

(C) liquifactive degeneration of the basal cell layer

32
Q

A characteristic pigmentation of the skin is associated with

     (A) lichen planus  

     (B) granuloma inguinale  

     (C) seborrheic keratosis  

     (D) actinic keratosis  

    (E) argyria
A 
     (E) argyria
33
Q

Dermal fibrosis, loss of elasticity , loss of adnexal structures , and epidermal atrophy are all features of typical skin lesions of

   (A) discoid lupus erythematosus  

   (B) erythema nodosum  

   (C) parapsoriasis  

  (D) progressive systemic sclerosis 

   (E) systemic lupus erythematosus
A 
   (D) progressive systemic sclerosis
34
Q

Which disease characteristically has grouped small vesicles on extensor areas and that are intensely pruritic ?

   (A) pemphigus vulgaris  

  (B) dermatitis herpetiformis 

   (C) bullous pemphigoid  

   (D) porphyria cutanea tarda  

   (E) erythema multiforme
A 
   (B) dermatitis herpetiformis
35
Q

Subepidermal vesicles on sun-exposed areas, facial hirsutism and urine abnormality are associated with

   (A) pemphigus vulgaris  

   (B) dermatitis herpetiformis  

   (C) bullous pemphigoid  

  (D) porphyria cutanea tarda 

   (E) erythema multiforme
A 
   (D) porphyria cutanea tarda
36
Q

Which skin disease is often caused by drugs or infections ?

   (A) pemphigus vulgaris  

   (B) dermatitis herpetiformis  

   (C) bullous pemphigoid  

   (D) porphyria cutanea tarda  

  (E) erythema multiforme
A 
   (E) erythema multiforme
37
Q

A tombstone appearance of the basal layer of the epidermis is characteristic of

   (A) dermatitis herpetiformis  

  (B) pemphigus vulgaris 

   (C) benign familial pemphigus  

   (D) Darier's disease  

   (E) bullous pemphigoid
A 
   (B) pemphigus vulgaris

MSSK (1 decks)

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