FA Synthesis Regulation

Question 1

Citrate synthase

Answer 1

• citrate, ATP, NADH, succinyl CoA

+ insulin, acetyl CoA, OAA

Question 2

Citrate lyase

Answer 2

• PUFA, leptin

+ glucose, insulin

Question 3

Acetyl CoA carboxylase

Answer 3

Inactivated dimer, active polymer
Requires biotin
- glucagon, epinephrine, high [AMP], palmitate, PUFA
+ citrate, insulin, high carb low fat diet

Question 4

Fatty acid synthase

Answer 4

• PUFA, high fat diet, starvation

+ insulin, glucocorticoid hormones, high carb low fat diet