FINAL Flashcards

1
Q
Pathogenic refers to \_\_\_\_\_\_\_\_\_\_\_\_\_\_.
A)	multicellular parasites
	B)	a disease or illness
	C)	potential to cause disease
	D)	weakening of the immune system
A

C

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2
Q
Infectious agents include all of the following except:
	A)	protozoans
	B)	fungi
	C)	viruses
	D)	protista
A

D

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3
Q
Viruses \_\_\_\_\_\_\_\_\_\_\_\_\_\_.
	A)	are obligate intracellular parasites
	B)	are similar in size to bacteria
	C)	can reproduce on their own
	D)	are microscopic single cell organisms
A

A

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4
Q
Where are dendritic immune cells located?
	A)	Blood
	B)	Spleen
	C)	Skin
	D)	Lungs
A

C

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5
Q
A function of \_\_\_\_\_\_\_\_\_\_\_\_\_\_ would be to alert neighboring cells of an infectious agent.
	A)	prions
	B)	cytokines
	C)	surveillance cells
	D)	B-lymphyocytes
A

B

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6
Q

Which of the following is incorrect?
A) Innate immunity does not require previous exposure to a foreign substance.
B) The digestive tract is the second line of defense of the acquired immunity.
C) Adaptive immunity typically takes several days to be effective.
D) The adaptive immunity and innate immunity are interdependent.

A

B

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7
Q
\_\_\_\_\_\_\_\_\_\_\_\_\_\_ helps provide the skin and mucosal membranes with a protective barrier.
	A)	Hyaluronic acid
	B)	Vibrissiae
	C)	Cdermumen
	D)	Low pH and mucus
A

A

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8
Q
Which cells of innate immunity are first to arrive during an inflammatory response?
	A)	Basophils
	B)	T-lymphocytes
	C)	Neutrophils
	D)	Eosinophils
A

C

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9
Q
NK (natural killer) cells perform all of these functions except:
	A)	immune surveillance
	B)	release neurotoxins
	C)	lysis by apoptosis
	D)	destruction of tumor cells
A

B

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10
Q
Stimulation of macrophages to destroy virus-infected cells in an effect of \_\_\_\_\_\_\_\_\_\_\_\_\_\_.
	A)	eicosanoids
	B)	natural killer cells
	C)	interferon
	D)	complement
A

C

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11
Q
Which complement protein binds to a portion of bacteria?
	A)	Membrane attack complex (MAC)
	B)	Interferon
	C)	Perforin
	D)	Opsonin
A

D

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12
Q

Inflammation is
A) the major effecter response of adaptive immunity.
B) an immediate local specific event that occurs in nonvascularized tissue.
C) successful in helping to eliminate most infectious agents.
D) a result of an immune deficiency disorder.

A

C

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13
Q
Chemotactic factors are released from \_\_\_\_\_\_\_\_\_\_\_\_\_\_.
	A)	mast cells
	B)	platelets
	C)	adhesion molecules
	D)	eosinophils
A

A

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14
Q
One measure of immunologic memory is
	A)	the extent of antigen exposure.
	B)	the rate of lymphocyte differentiation.
	C)	antibody titer in the blood.
	D)	the length of the latent phase.
A

C

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15
Q
In severe infections pus may form, which is \_\_\_\_\_\_\_\_\_\_\_\_\_\_.
	A)	an abcess
	B)	an exudate
	C)	swelling
	D)	infectious fluid
A

B

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16
Q
The \_\_\_\_\_\_\_\_\_\_\_\_\_\_ region of an antibody binds to an antigen.
	A)	Fab
	B)	Cytotoxic
	C)	Perforin
	D)	Apoptosis
A

A

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17
Q
Which of the following is NOT a sign of inflammation?
	A)	Increased blood flow
	B)	Stimulation of pain receptors
	C)	Vasoconstriction of blood vessels
	D)	Loss of function
A

C

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18
Q
Which of the following fever events would cause the hypothalamus to stimulate blood vessels in the skin to vasoconstrict?
	A)	Onset
	B)	Pyrexia
	C)	Stadium
	D)	Defervescence
A

A

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19
Q
Which immunoglobulin class is formed in response to allergic reactions?
	A)	IgG
	B)	IgA
	C)	IgE
	D)	IgD
A

C

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20
Q
The presence of memory lymphocytes \_\_\_\_\_\_\_\_\_\_\_\_\_\_.
	A)	delays immune response
	B)	decreases latent phase
	C)	assists primary response
	D)	increases lag phase
A

B

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21
Q
Plasma cells are derived from \_\_\_\_\_\_\_\_\_\_\_\_\_\_.
	A)	cytotoxic lymphocytes
	B)	killer T-cells
	C)	memory lymphocytes
	D)	B-lymphocytes
A

B

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22
Q
The function of a vaccine is to
	A)	administer live microorganisms.
	B)	increase T-lymphocytes.
	C)	establish an infection.
	D)	develop memory B-lymphocytes.
A

D

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23
Q

Active immunity results from
A) the transfer of antibodies from mother to fetus.
B) production of memory cells.
C) direct encounter with a pathogen.
D) the transfer of cells from another individual.

A

C

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24
Q
The lymphatic system helps maintain blood volume by
	A)	transporting lymphocytes.
	B)	regulating vessel fluids.
	C)	aiding the cardiovascular system.
	D)	functions of the spleen.
A

C

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25
Q

Which of these listed characteristics do not describe lymph?
A) Associated with the central nervous system
B) Originates in interstitial fluid
C) Can contain cell debris and pathogens
D) Amounts to about 3 liters a day

A

A

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26
Q
Lymphatic vessels are similar to \_\_\_\_\_\_\_\_\_\_\_\_.
	A)	deep arteries
	B)	small veins
	C)	pumping vessels
	D)	capillaries
A

B

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27
Q
Lymphatic capillaries are NOT found in \_\_\_\_\_\_\_\_\_\_\_\_.
	A)	areolar connective tissue
	B)	muscle
	C)	epithelia
	D)	intestinal walls
A

C

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28
Q
Which vessel is responsible for draining lymph from deep thoracic structures?
	A)	Intestinal trunk
	B)	Thoracic duct
	C)	Bronchomediastinal trunk
	D)	Lymphatic duct
A

C

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29
Q
The only primary lymphatic structure in this list is the \_\_\_\_\_\_\_\_\_\_.
	A)	spleen
	B)	tonsils
	C)	MALT
	D)	thymus
A

D

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30
Q
The process of wandering cancer cells from a primary tumor establishing a secondary tumor is referred to as \_\_\_\_\_\_\_\_\_\_\_.
	A)	breast cancer
	B)	pathology
	C)	metastisis
	D)	lymphedema
A

C

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31
Q

The right lymphatic duct
A) drains lymph from the upper half of the body.
B) returns lymph to right internal jugular vein.
C) drains lymph from cisterna chyli.
D) extends from right side of the diaphragm.

A

B

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32
Q
Where would an immune response be initiated?
	A)	Mucosa-associated lymphatic tissue
	B)	Immune response system
	C)	Thymus
	D)	Lymphatic vessel
A

A

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33
Q

Which description is NOT accurate?
A) Formed elements are produced in red bone marrow through the process of hemopoiesis.
B) The hormones thymosin, thymulin, and thymopoietin are produced in the thymus.
C) All formed elements leave the bone morrow and directly enter the blood and circulate.
D) An adult thymus has lost thymic tissue and gained adipose connective tissue.

A

C

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34
Q
Which of the following can be found in every organ?
	A)	peyers patches
	B)	white pulp
	C)	secondary structures
	D)	diffuse lymphatic tissue
A

D

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35
Q

The function of the spleen is to
A) help support formation of formed elements.
B) filter lymph before it returns to the blood.
C) promote lymphocyte maturation.
D) filter the blood and help initiate an immune response.

A

D

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36
Q
Which of the following formed elements does not mature in the blood?
	A)	Basophils
	B)	T-lymphocytes
	C)	Eosionphils
	D)	Neutrophils
A

B

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37
Q
Hemorrhaging could cause platelets to re-enter the blood from \_\_\_\_\_\_\_\_\_\_.
	A)	splenic artery
	B)	red pulp
	C)	plasma
	D)	bone marrow
A

B

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38
Q
Adenoids are
	A)	enlarged pharyngeal tonsils.
	B)	clusters of lymph nodes.
	C)	enlarged lingual tonsils.
	D)	hormones produces by the thymus.
A

A

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39
Q

From innermost to outermost, what is the correct order of tissue layers in the kidney?
A) Renal fascia, paranephric fat, perinephric fat, fibrous capsule
B) Paranephric fat, perinephric fat, fibrous capsule, renal fascia
C) Fibrous capsule, perinephric fat, renal fascia, paranephric fat
D) Perinephric fat, fibrous capsule, renal fascia, paranephric fat

A

C

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40
Q
The microscopic, functional filtration unit of the kidney is the
	A)	renal corpuscle.
	B)	glomerulus.
	C)	tubular pole.
	D)	nephron.
A

D

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41
Q
The region of the kidney that drains urine is the
	A)	renal papilla.
	B)	renal sinus.
	C)	renal column.
	D)	renal pyramid.
A

B

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42
Q
Which is not part of a renal tubule?
	A)	Glomerulus
	B)	Proximal convoluted tubule
	C)	Nephron loop
	D)	Distal convoluted tubule
A

A

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43
Q
Intercalated cells
	A)	regulate urine concentration.
	B)	regulate urine and blood pH.
	C)	establish a salt gradient.
	D)	drain urine.
A

B

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44
Q
The blood vessels that carry blood away from the glomerulus are the
	A)	segmental arteries.
	B)	interlobular arteries.
	C)	arcuate arteries.
	D)	efferent arteries.
A

D

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45
Q
the cells that synthesize, store, and release renin are the \_\_\_\_\_\_\_\_ cells.
	A)	granular
	B)	cortical
	C)	principal
	D)	intercalated
A

A

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46
Q

What is the pathway that urine follows from its formation until its excretion?
A) Renal sinus, papillary duct, urethra, urinary bladder, ureter
B) Papillary duct, renal sinus, ureter, urinary bladder, urethra
C) Renal sinus, urinary bladder, papillary duct, urethra, ureter
D) Urethra, renal sinus, papillary duct, urinary bladder, ureter

A

B

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47
Q
The movement of solutes, usually by active transport, out of the blood and into the tubular fluid is called
	A)	filtration.
	B)	tubular reabsorption.
	C)	tubular secretion.
	D)	hydrostatic movement.
A

C

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48
Q

Which of the following is not normally filtered through the glomerular filtration membrane?
A) Glucose
B) Formed elements (erythrocytes, leukocytes, and platelets)
C) Hormones
D) Vitamins B and C

A

B

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49
Q
What is the value of the NFP (net filtration pressure) if the glomerular hydrostatic pressure (HPg) is 60mm Hg, the blood colloid osmotic pressure (OPg) is 32mm Hg, and the capsular hydrostatic pressure (HPc) is 18mm Hg?
	A)	0 mm Hg
	B)	10 mm Hg
	C)	46 mm Hg
	D)	74 mm Hg
A

B

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50
Q
What hormone increases the glomerular filtration rate (GFR) in response to distension of cardiac chambers due to an increase in blood volume or pressure?
	A)	Aldosterone
	B)	Antidiuretic hormone
	C)	Atrial natriuretic peptide hormone
	D)	Renal plasma hormone
A

C

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51
Q
The maximum plasma concentration of a substance that can be carried in the blood without eventually appearing in the urine is called
	A)	transport maximum.
	B)	paracellular transport threshold.
	C)	net filtration concentration.
	D)	renal threshold.
A

D

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52
Q
Water reabsorption in the proximal convoluted tubule occurs via
	A)	osmosis.
	B)	active transport.
	C)	exchange pumps.
	D)	facilitated diffusion.
A

A

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53
Q

What is the effect of an increase in antidiuretic hormone (ADH) on urine production?
A) It decreases the volume of urine produced and creates a more concentrated urine.
B) It increases the volume of urine produced and creates a more dilute urine.
C) It creates urine with a higher pH value.
D) It creates urine with a lower pH value.

A

A

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54
Q
A decrease in blood pressure would result in
	A)	an increase in sweating.
	B)	a decrease in the thirst mechanism.
	C)	an increase in urine volume.
	D)	a decrease in urine volume.
A

D

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55
Q

What statement is true regarding the ureters?
A) The ureters use gravity to move the urine to the bladder.
B) The ureters use smooth muscle contraction to actively move urine to the urinary bladder.
C) The ureters use gravity to move the urine to the urethra.
D) The ureters use smooth muscle contraction to actively move urine to the urethra.

A

B

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56
Q
What is the innermost tunic of the bladder?
	A)	Mucosa
	B)	Submucosa
	C)	Muscularis
	D)	Adventitia
A

A

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57
Q

What statement is true regarding the differences between the urethra of a male and a female?
A) The male urethra is shorter than the female urethra.
B) The male urethra has both reproductive and urinary functions.
C) The female urethra has both reproductive and urinary functions.
D) The female urethra is partitioned into three segments, while there is only one segment in the male urethra.

A

B

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58
Q
The expulsion of urine from the bladder is called
	A)	the urethral reflex.
	B)	the prostatic reflex.
	C)	micturition.
	D)	continence.
A

C

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59
Q
The human body is composed of an average of \_\_\_\_\_\_ fluid by weight.
	A)	25%
	B)	45%
	C)	65%
	D)	85%
A

C

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60
Q

Which of the following situations would result in a relatively higher percentage of body fluid?
A) An increase in skeletal muscle tissue
B) An increase in adipose connective tissue
C) An increase in age
D) An increase in bone density

A

A

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61
Q

What situations would result in a net movement of water from the cells into the blood plasma?
A) Drinking two large cups of water
B) Becoming dehydrated
C) A decrease in plasma osmolarity
D) The intracellular compartment becomes hypertonic

A

B

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62
Q
The loss of water that always occurs, regardless of the state of hydration of the body is called
	A)	sensible water loss.
	B)	insensible water loss.
	C)	obligatory water loss.
	D)	facultative water loss.
A

C

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63
Q
What stimuli would activate (turn on) the thirst center?
	A)	Increased blood pressure
	B)	Decreased blood osmolarity
	C)	Distension of the stomach
	D)	Decreased salivary secretions
A

D

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64
Q

What statement is true regarding electrolytes?
A) Electrolytes decrease osmotic pressure.
B) Electrolytes dissociate in water.
C) Electrolytes include glucose, urea, and creatinine.
D) Electrolytes do not conduct an electric current.

A

B

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65
Q
What conditions would result in an increase in blood pressure?
	A)	Na+ (sodium) intake is increased.
	B)	The ECF becomes hypotonic.
	C)	The plasma volume decreases.
	D)	Sodium loss in urine increases.
A

A

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66
Q
The most abundant anion in the ECF is
	A)	sodium.
	B)	potassium.
	C)	chloride.
	D)	calcium.
A

C

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67
Q

What is an effect of Angiotensin II?
A) Stimulates vasoconstriction of systemic blood vessels, thereby increasing blood pressure
B) Increases urine output in order to decrease blood pressure
C) Inhibits the thirst center in the hypothalamus
D) Inhibits the release of ADH from the posterior pituitary

A

A

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68
Q
ADH is released in response to
	A)	hormones from the hypothalamus.
	B)	nerve signals from the hypothalamus.
	C)	an increase in blood chloride levels.
	D)	an increase in blood pressure.
A

B

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69
Q

One effect of aldosterone release is
A) a decrease in potassium (K+) secretion in to tubular fluid.
B) an increase of sodium (Na+) reabsorption into the blood.
C) a decrease in the reabsorption of water.
D) an increase in urine output.

A

B

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70
Q

How does ANP influence blood volume and blood pressure?
A) ANP causes the constriction of blood vessels.
B) ANP causes vasoconstriction of the afferent arterioles in the kidneys.
C) ANP inhibits Na+ and water reabsorption by nephron tubules in the kidneys.
D) ANP decreases urine output.

A

C

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71
Q
The acid-base balance requires the regulation of hydrogen concentration in body fluids in order to maintain an arterial blood pH that is
	A)	between 3.5 and 3.75.
	B)	between 4 and 4.25.
	C)	between 7.35 and 7.45.
	D)	between 8.25 and 8.35.
A

C

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72
Q

When alkaline conditions are present, how do the renal tubules respond in order to maintain the acid-base balance?
A) They reabsorb more HCO3 - in the nephron tubule.
B) The decrease the secretion HCO3- from the blood into the filtrate.
C) They reabsorb more H+ from the filtrate.
D) They secrete Na+ into the filtrate.

A

C

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73
Q
What would an increase in respiratory rate cause?
	A)	Blood CO2 levels are increased.
	B)	Blood H+ concentration increases.
	C)	Decreased levels of CO2 are expired.
	D)	Blood pH levels increase.
A

D

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74
Q

The protein buffering system acts in what way to maintain body fluid pH?
A) It can act as a weak acid or a weak base to minimize pH changes in the body.
B) It acts as a strong acid to buffer bases in the body.
C) It acts as a strong base to buffer acids in the body.
D) It acts as neither an acid nor a base.

A

A

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75
Q
The response of physiologic buffering systems to acid-base disturbances that results in the return of blood pH to normal is called
	A)	acid-base disturbance.
	B)	compensation.
	C)	uncompensation.
	D)	acid-base imbalance.
A

B

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76
Q
Respiratory acidosis is defined as occurring when the PCO2 in the arterial blood becomes elevated above
	A)	15 mm Hg
	B)	35 mm Hg
	C)	45 mm Hg
	D)	60 mm Hg
A

C

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77
Q
The acid-base disturbance that occurs as a result of a decrease in HCO3- is called
	A)	metabolic acidosis.
	B)	metabolic alkalosis.
	C)	respiratory alkalosis.
	D)	renal acidosis.
A

A

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78
Q

In response to low pH, how would renal compensation help return the body to a normal pH level?
A) Excess CO2 is eliminated.
B) Decreases the elimination of CO2.
C) Excess H+ is eliminated and HC03- is reabsorbed.
D) H+ is reabsorbed and excess HC03- is eliminated.

A

A

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79
Q
The primary reproductive organs in females and males are called
	A)	gametes.
	B)	greater vestibular glands.
	C)	gonads.
	D)	glans.
A

C

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80
Q

The organs that produce gametes and sex hormones are the
A) ovaries and testis.
B) greater vestibular gland and bulbourethral gland.
C) accessory reproductive organs.
D) labia majora and glans of penis.

A

A

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81
Q
When the hypothalamus begins secreting \_\_\_\_\_\_\_\_\_\_\_\_\_\_, puberty is initiated.
	A)	gametes
	B)	growth hormone
	C)	prolactin
	D)	gonadotropin-releasing hormone
A

D

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82
Q
Which of the following is NOT a component of the urogenital triangle?
	A)	Anus
	B)	Vaginal orifices
	C)	Base of the penis
	D)	Scrotum
A

A

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83
Q
Human somatic (body) cells contain \_\_ pair(s) of autosomes, and \_\_\_ pair(s) of sex chromosomes.
	A)	46; 2
	B)	22; 1
	C)	1; 23
	D)	16; 2
A

B

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84
Q

Which of the following statements is true regarding meiosis?
A) Meiosis is the division of somatic cells.
B) Meiosis results in two daughter cells that are genetically identical to the parent cell.
C) Meiosis involves a process called crossing over.
D) Meiosis produces daughter cells that are diploid.

A

C

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85
Q
The cell division that is also known as the reduction division is \_\_\_\_\_\_\_\_\_\_.
	A)	meiosis I
	B)	meiosis II
	C)	mitosis I
	D)	mitosis II
A

A

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86
Q
During \_\_\_\_\_\_\_\_\_\_\_, the homologous pairs of replicated chromosomes line up above and below the equator of the cell, forming a double line of chromosomes.
	A)	prophase I
	B)	metaphase I
	C)	anaphase I
	D)	telophase I
A

B

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87
Q
Which of the following is NOT an accessory reproductive organ in human females?
	A)	Uterine tubes
	B)	Uterus
	C)	Vagina
	D)	Ovaries
A

D

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88
Q

Which of the following represents the correct order of ovarian follicle development?
A) Vesicular follicle, primary follicle, secondary follicle, primordial follicle
B) Primordial follicle, primary follicle, secondary follicle, vesicular follicle
C) Primary follicle, secondary follicle, vesicular follicle, primordial follicle
D) Secondary follicle, primordial follicle, vesicular Follicle, primary follicle

A

B

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89
Q
The follicle that contains a secondary oocyte is the \_\_\_\_\_\_\_\_\_\_\_ follicle.
	A)	vesicular
	B)	secondary
	C)	primary
	D)	primordial
A

A

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90
Q
Ovulation occurs on day \_\_\_\_ of a 28-day ovarian cycle.
	A)	5
	B)	9
	C)	14
	D)	21
A

C

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91
Q
he end of the luteal phase is marked by
	A)	menses.
	B)	ovulation.
	C)	puberty.
	D)	oogenesis.
A

A

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92
Q
The broad, curved superior region of the uterus is the
	A)	cervix.
	B)	isthmus.
	C)	body.
	D)	fundus.
A

D

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93
Q
The \_\_\_\_\_\_\_\_\_\_\_ is(are) the site(s) of sperm cell production in the testes.
	A)	seminiferous tubules
	B)	tunica albuginea
	C)	ductus deferens
	D)	venous spaces
A

A

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94
Q

Which is the correct path of gametes through the male reproductive tract?
A) Ejaculatory duct, ductus deferens, epididymis, efferent ductules
B) Ductus deferens, efferent ductules, Ejaculatory duct, epididymis
C) Efferent ductules, epididymis, ductus deferens, ejaculatory duct
D) Epididymis, efferent ductules, ejaculatory duct, ductus deferens

A

C

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95
Q

The function of the seminal vesicles is to
A) secrete a viscous fluid containing fructose and prostaglandins.
B) secrete mucus to serve as a lubricant during sexual intercourse.
C) secrete an acidic fluid rich in citric acid.
D) secrete spermatozoa into the ejaculate.

A

A

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96
Q

How do parasympathetic and sympathetic innervation work together in the male reproductive system?
A) Sympathetic innervation is needed to achieve an erection, while parasympathetic innervation promotes ejaculation.
B) Parasympathetic innervation is needed to achieve an erection, while sympathetic innervation promotes ejaculation.
C) Sympathetic innervation promotes sperm development, and parasympathetic innervation promotes an erection.
D) Parasympathetic innervation is needed to enter the refractory period, and sympathetic innervation promotes the resolution phase.

A

B

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97
Q

Which of the following statements regarding genetic and phenotypic sex is NOT true?
A) A person with one X and one Y chromosome is a genetic male.
B) Phenotypic sex refers to the appearance of an individual’s genitalia.
C) If the Y chromosome has an abnormal SRY gene, a female phenotypic sex results.
D) It is impossible for an individual to be a genetic male and have a female phenotypic sex.

A

D

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98
Q
Menopause typically occurs
	A)	between the ages of 35 and 45.
	B)	between the ages of 45 and 55.
	C)	between the ages of 65 and 75.
	D)	after age 75.
A

B

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99
Q
The process by which two gametes fuse together to form a new diploid cell containing genetic material from both parents is called
	A)	capacitation.
	B)	fertilization.
	C)	acrosome reaction.
	D)	cleavage.
A

B

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100
Q
The period of time that begins with fertilization and ends two weeks later is called the
	A)	pre-embryonic period.
	B)	embryonic period.
	C)	fetal period.
	D)	prenatal period.
A

A

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101
Q

What is the correct order of the developmental stage or process during pre-embryonic development?
A) Cleavage, blastocyst, implantation, zygote, morula
B) Cleavage, blastocyst, implantation, morula, zygote
C) Zygote, cleavage, morula, blastocyst, implantation
D) Implantation, zygote, morula, cleavage, zygote

A

C

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102
Q

Which of the following statements is true regarding cleavage?
A) The overall size of the pre-embryo increases in relation to an increase in cell number.
B) There is an increase in cell number, but not an increase in the size of the pre-embryo.
C) It occurs following implantation.
D) It ends when the pre-embryo reaches the 2-cell stage.

A

B

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103
Q
The physiological conditioning that makes it possible for the sperm to penetrate the egg is called
	A)	sperm migration.
	B)	capacitation.
	C)	morulation.
	D)	cleavage.
A

B

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104
Q

Which is not a function of the placenta?
A) Exchange of metabolic products between fetal and maternal blood
B) Exchange of respiratory gases between fetal and maternal blood
C) Hormone production
D) Blockage of maternal antibodies

A

D

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105
Q
The embryonic period extends from
	A)	fertilization to week 3.
	B)	week 3 to week 8.
	C)	week 8 through week 16.
	D)	week 16 through birth.
A

B

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106
Q
Almost all of organogenesis occurs
	A)	during the pre-embryonic period.
	B)	during the embryonic period.
	C)	during the fetal period.
	D)	after birth.
A

B

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107
Q
During which period of development does the fetus experience its most rapid period of growth?
	A)	Pre-embryonic period
	B)	First trimester
	C)	Second trimester
	D)	Third trimester
A

D

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108
Q

Which of the following statements is true regarding maternal hormonal changes during pregnancy?
A) HCG peaks during the first trimester and its levels drop thereafter.
B) Prolactin and oxytocin levels decrease toward the end of pregnancy.
C) Levels of estrogen and progesterone decrease after the second trimester.
D) Human placental lactogen (HPL) peaks during the first trimester and drops thereafter.

A

A

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109
Q

True labor is initiated due to __________ being released by the fetus and the mother, causing a _________ feedback cycle.
A) progesterone; positive
B) estrogen; negative
C) oxytocin; positive
D) human chorionic gonadotropin; negative

A

C

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110
Q

Which of the following events occurs during the expulsion stage of labor?
A) The uterus experiences rhythmic contractions and the cervix dilates to 10 centimeters.
B) The baby is expelled from the mother’s body.
C) The placenta and fetal membranes are expelled from the uterus.
D) The fetus secretes oxytocin, causing the cervix to stretch.

A

B

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111
Q
Ectoderm gives rise to
	A)	most of the cardiovascular system.
	B)	most muscle.
	C)	cartilage and connective tissue.
	D)	epidermis, hair, and sense organs.
A

D

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112
Q
The hormone that is responsible for milk production is
	A)	prolactin.
	B)	human chorionic thyrotropin.
	C)	relaxin.
	D)	estrogen.
A

A

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113
Q

After giving birth, the mother experiences which of the following changes?
A) Blood volume and cardiac output increase
B) Estrogen and progesterone levels rise
C) Respiratory rate and pulmonary ventilation decrease
D) Fluid retention increases

A

C

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114
Q
The physical expression of a genetic trait in an individual is called the
	A)	allele.
	B)	locus.
	C)	genotype.
	D)	phenotype.
A

D

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115
Q
If a person has two identical alleles for a trait, the individual is said to be \_\_\_\_\_\_\_\_\_\_ for that trait.
	A)	homozygous
	B)	heterozygous
	C)	incompletely dominant
	D)	autosomal
A

A

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116
Q
If one parent has a dominant allele for a trait, and the other parent has a recessive allele for the same trait, the offspring will express the \_\_\_\_\_\_\_\_\_ allele.
	A)	dominant
	B)	recessive
	C)	homozygous
	D)	incompletely dominant
A

A

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117
Q
The practice of incising the perineal muscles in order to create a wider opening for the baby to pass through during childbirth is called a(n)
	A)	crowning procedure.
	B)	episiotomy.
	C)	lochia.
	D)	dilation.
A

B

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118
Q
The block-like masses that are responsible for the formation of the axial skeleton, most musculature, and most of the cartilage, dermis, and connective tissues of the body are
	A)	intermediate mesoderm.
	B)	lateral plate mesoderm.
	C)	head mesenchyme.
	D)	somites.
A

D

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119
Q

The tissue of which organ is called pulp?

A.thymus
B.spleen
C.lymph nodes
D.tonsils

A

B

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120
Q

The structure of a lymphatic vessel is most similar to that of a(n)

A.artery
B.arteriole
C.vein
D.capillary

A

C

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121
Q

The two collecting ducts that drain the lymphatic trunks are the

A.thoracic duct and right lymphatic duct
B.thoracic duct and left lymphatic duct
C.subclavian duct and bronchomediastinal duct
D.cisterna chyli and thoracic duct

A

A

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122
Q

Lymph nodes of the axillary region receive lymph primarily from the

A.scalp and face
B.arm and mammary gland
C.thoracic viscera
D.abdominal viscera

A

B

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123
Q

The thoracic duct

A.empties into the right subclavian vein
B.drains the right side of the head and neck
C.is the shorter of the two collecting ducts
D.drains lymph from most of the body

A

D

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124
Q

Afferent lymph vessels

A.carry lymph toward lymph nodes
B.carry lymph toward the thoracic duct
C.enter a lymph node at the hilum
D.combine to form lacteals

A

A

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125
Q

The functions of the lymphatic system include

A.draining excess interstitial fluid
B.transporting dietary lipids
C.carrying out immune responses
D.all of these Choices

A

D

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126
Q

Lymphatic vessels are lined with

A.ciliated columnar epithelium
B.pseudostratified ciliated epithelium
C.endothelium
D.white fibrous connective tissue

A

C

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127
Q

Medullary sinuses of lymph nodes

A.are filled with lymph
B.contain germinal centers
C.filter blood
D.are strands of lymphocytes

A

A

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128
Q

Lymph from the cisterna chyli empties into the

A.liver
B.thoracic duct
C.left brachiocephalic vein
D.heart

A

B

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129
Q

The largest single mass of lymphatic tissue in the adult human body is the

A.liver
B.spleen
C.thymus
D.pancreas

A

B

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130
Q

All of these choices are non-specific defense mechanisms except

A.flow of saliva
B.phagocytosis
C.neutralization of an antigen by an antibody
D.gastric juice acidity

A

C

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131
Q

Lymphocytes that destroy cancerous cells in a non-specific fashion are called:

A.carcinolytic cells
B.natural killer cells
C.cytotoxic T cells
D.macrophages

A

B

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132
Q

Which of the following does NOT function to increase vasodilation and permeability of blood vessels?

A.defensins
B.histamine
C.prostaglandins
D.kinins

A

A

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133
Q

Interferon is produced in response to the presence of

A.viruses
B.specific bacterial cells
C.chemical irritants
D.lymphocytes

A

A

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134
Q

The two major types of phagocytic cells are

A.monocytes and eosinophils
B.macrophages and neutrophils
C.neutrophils and macrophages
D.monocytes and lymphocytes

A

C

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135
Q

Which of the following cell types is derived from monocytes?

A.neutrophil
B.wandering macrophage
C.mast cell
D.histiocyte

A

B

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136
Q

Which of the following cell types is derived from monocytes?

A.neutrophil
B.wandering macrophage
C.mast cell
D.histiocyte

A

C

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137
Q

Emigration refers to the

A.release of lymphokines
B.lysis of cell walls by lymphotoxins
C.apoptosis of cells
D. movement of cells from the circulatory system into infected areas

A

D

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138
Q

The proper sequence of phases in the process of phagocytosis is

A.adherence, ingestion, chemotaxis B.adherence, chemotaxis, ingestion
C.chemotaxis, adherence, ingestion
D. chemotaxis, ingestion, adherence

A

C

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139
Q

After phagocytosis, which intracellular chemicals kill the microbe by a process called an oxidative burst?

A.lethal oxidants
B.lysozyme
C.defensins
D.complement

A

A

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140
Q

The first stage of inflammation is

A.tissue repair
B.vasodilation and increased permeability of blood vessels
C.phagocyte migration and cytolysis by complement
D.activation of cell mediated immunity

A

B

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141
Q

The lymphokine interleukin – 2

A.is toxic only to the target cells
B.promotes phagocytic activity
C.attracts leukocytes chemically
D.stimulates T-cell proliferation

A

D

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142
Q

Which of the following is a specific body defense mechanism?

A.phagocytosis
B.inflammation
C.immunity
D.fever

A

C

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143
Q

Normal immune responses require the presence of

A. B lymphocytes
B. T lymphocytes
C. both T lymphocytes and B lymphocytes
D. NK cells

A

C

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144
Q

A hapten is an antigen that has

A.immunogenicity but not reactivity
B.reactivity but not immunogenicity
C.both immunogenicity and reactivity
D.neither immunogenicity nor reactivity

A

B

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145
Q

Interleukin – 1

A.is toxic only to the target cells
B.promotes phagocytic activity
C.initiates chemotaxis
D.is a fever-causing cytokine

A

D

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146
Q

B lymphocytes

A.migrate from the thymus to other lymphatic organs
B.are responsible for antibody-mediated immunity
C.secrete lymphokines
D.are phagocytic

A

B

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147
Q

The Class I major histocompatibility complex (MHCI) antigens

A.are a large group of bacterial related antigens that cause many diseases
B.are located only on viruses, not bacteria
C.are difficult to produce antibodies against because they are constantly mutating
D.mark the surfaces of all your body cells except your red blood cells

A

D

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148
Q

Antigen presenting cells (APCs) include

A.macrophages
B.killer T cells
C.neutrophil
D.plasma cells

A

A

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149
Q

Antigen recognition by a T-cell receptor with CD4 or CD8 proteins is the ____________________ in the activation of a T-cell.

A.first signal
B.second signal
C.third signal
D.fourth signal

A

A

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150
Q

When stimulated, T cells that display the CD8 molecule develop into

A.plasma cells
B.cytotoxic T cells
C.memory cells
D.helper T cells

A

B

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151
Q

Cytotoxic T cells can kill target cells directly by secreting

A.cytokines
B.antibodies
C.lysozyme
D.perforin and granulysin

A

D

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152
Q

The most abundant type of immunoglobin is

A.IgA
B.IgD
C.IgE
D.IgG

A

D

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153
Q

After recovering from certain diseases, one may have developed _____ immunity to the diseases.

A.naturally acquired active
B.artificially acquired active
C.naturally acquired passive
D.artificially acquired passive

A

A

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154
Q

The antibodies involved in allergic reactions are:

A.called allergens
B.secreted by mast cells
C.in the IgE class
D.produced only after immunization

A

C

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155
Q

An immunoglobulin is

A.an antigen
B.an antibody
C.a nucleoprotein
D.found in platelets

A

B

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156
Q

Complement:

A.is produced by eosinophils and neutrophils

B.is chemotactic and attracts phagocytic cells

C.contains enzymes which reduce the inflammatory response

D.lyses B-cells, thus releasing antibodies

A

B

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157
Q

An activated B cell develops into a clone of

A. T cells
B.Natural Killer cells
C.antibody-producing plasma cells
D.IgG antibodies

A

C

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158
Q

Antibodies are composed of

A.1 heavy and 3 light polypeptide chains
B.2 heavy and 2 light polypeptide chains
C.2 heavy and 2 light polysaccharide chains
D. 1 light and 3 heavy polysaccharide chains

A

B

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159
Q

Lack of reactivity of T cells and B cells to fragments of one´s own proteins is known as

A.self-tolerance
B.self-recognition
C.positive selection
D.negative selection

A

A

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160
Q

A tissue transplant in which one’s own tissue is grafted to another part of the body is called

A) an autograft
B) an isograft
C).an allograft
D)a xenograft

A

A

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161
Q

The immune cells that are very ‘macrophage-like’ and are found in almost all tissues are called

A) Plasma cells
B) Dendritic cells
C) Mast cells
D) Lymphocytes

A

B

Dendritic cells possess almost all the characteristics of macrophages, but they are not derived from monocytes. They reside in almost all the body’s tissues.

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162
Q

Secretions such as sweat, tears, saliva, and mucous are important components of the body’s innate immune responses (nonspecific)

T/F

A

T

This statement is true. These secretions contain antibacterial chemicals such as lysozyme and lactoferrin that are harmful to bacteria. Furthermore, because mucous is sticky, it traps bacteria in respiratory and digestive tracts.

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163
Q

Which of the following is NOT a typical event of inflammation?

A) Increased vasodilation and capillary permeability
B) Release of inflammatory mediators
C) Release of specific antibodies
D) Increased rates of phagocytosis

A

C

Antibody production is an adaptive immune response while inflammation is an innate immune response. Inflammation is a complex process beginning with the release of inflammatory mediators that increase vasodilation and capillary permeability. These events allow phagocytes to move into the infected area leading to an increase in phagocytosis.

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164
Q

Chemotaxis

A) Refers to the chemical attraction of erythrocytes to the site of inflammation

B) Is the mechanism by which neutrophils and monocytes migrate to the scene of microbial invasion or injury

C) Is responsible for the activation of lymphocytes in the innate immune response

D) Is stimulated by the presence of antibodies

A

B

hemotaxis is the chemically-mediated movement of neutrophils and monocytes to an area of injury or infection. Erythrocytes do not participate in the immune response, and antibody production by B-lymphocytes requires antigen binding and stimulation by cytokines

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165
Q

Which of the following statements regarding phagocytes and phagocytosis is true?

A) Lymphocytes can act as phagocytes

B) Contact of phagocytes with microbes stimulates the phagocytes to release chemicals that stimulate the inflammatory response

C) Phagocytosis is stimulated by the presence of proteins called rhodopsins

D) Phagocytosis is a negative feedback regulation of inflammation

A

B

Contact with microbes causes the phagocytes to release chemicals into the extracellular fluid that stimulate the inflammatory response. Lymphocytes are not phagocytic cells. The primary phagocytic cells are neutrophils, dendritic cells, and macrophages. Phagocytosis is stimulated by a variety of proteins referred to as opsonins, but rhodopsin is not one of these proteins (it is a photosensitive protein found in the retina). Phagocytosis provides a positive feedback mechanism for inflammation.

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166
Q

Which of the following statements regarding phagocytosis is true?

A) Macrophages are the only phagocytes in the tissues

B) The microbe engulfed by the phagocyte is killed by lysosomal enzymes and hydrogen peroxide

C) Phagocytosis is controlled by a negative feedback mechanism whereby phagocytes release chemicals that inhibit further phagocytosis

D) The microbe engulfed by the phagocyte is killed by the membrane attack complex (MAC)

A

B

Enzymes in the phagolysosome, including enzymes that generate hydrogen peroxide, destroy the microbe. The lysosomes produce nitric oxide and hydrogen peroxide both of which damage the microbe’s macromolecules. Macrophages are not the only phagocytes that are found in tissues; dendritic cells and neutrophils are also phagocytic. When phagocytes become activated, they release cytokines that activate other phagocytes; this is a form of positive feedback regulation. Phagocytes do not kill cells via a membrane attack complex (MAC) mechanism, but rather by lysosomal digestion of the microbe. MAC is produced by the complement protein system and results in lytic destruction of the microbe.

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167
Q

The membrane attack complex (MAC) is composed of

A)	Complement proteins

B)	Chemokines

C)	Cytokines

D)	C-reactive proteins
A

A

omplement proteins form the membrane attack complex in response to activation by infection or tissue damage. Cytokine is a general term that refers to protein messengers secreted by the cells of the immune system. Chemokines are a group of cytokines that have chemoattractant actions. C-reactive proteins are plasma protein that can act as opsonins.

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168
Q

Interferons

A) Are synthetic drugs developed to combat viruses

B) Are a type of antibody

C) Are a family of cytokines that inhibit viral replication of specific viruses

D) Are a family of cytokines that non-specifically inhibit viral replication inside host cells

E) Are mainly secreted by lymphoid organ cells in response to viral infections

A

D

Interferons inhibit replication of viruses inside target cells but do so non-specifically. Interferons are a family of cytokines (proteins released by the cells of the immune system) that are released from many types of body tissues in response to viral attack. Interferons have been successful in treating viral hepatitis and similar diseases.

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169
Q

Foreign molecules that can trigger an adaptive immune response are called

A) Immunoglobulins

B) Antigens

C) Antibodies

D) Cytokines

A

B

Antigens are foreign molecules that can initiate an immune response. Antigens are bound by immunoglobulins, also known as antibodies. Cytokines are chemicals used for cell to cell communication and are secreted by a variety of cells.

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170
Q

Lymphocytes express hundreds of distinct antigen receptors. This increases the likelihood that a given lymphocyte will be able to bind a foreign organism.

T/F

A

F

This statement is false. Each lymphocyte expresses only a single type of antigen receptor. Thus, each lymphocyte is specific for just one type of antigen. If that lymphocyte binds an antigen and becomes activated, it will make many copies of itself (clones), all capable of producing more copies of that antigen receptor.

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171
Q

The ability to vaccinate individuals against a disease is possible because memory cells are produced by clonal expansion, and they allow for a rapid response if an antigen should return.

T/F

A

T

This statement is true. Memory cells produced by clonal expansion are rapidly activated by a return of an antigen. Vaccinations involve administration of killed or incapacitated microbes to allow the immune system to mount an immune response without any danger of actually acquiring an infection. This immune response produces the memory cells that prevent future infection by the same organism.

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172
Q

Which of the following statements regarding lymphoid organs is NOT correct?

A) The spleen is the largest primary lymph organ

B) Lymph nodes and tonsils are examples of secondary lymphoid organs

C) Bone marrow and thymus are examples of primary lymphoid organs

D) Mature lymphocytes of the secondary lymphoid organs originate from bone marrow and thymus

A

A

The spleen is the largest secondary lymph organ. Only bone and the thymus gland are primary lymph organs. Lymphoid organs are the organs which deal with production and maintenance of lymphocytes. The primary organs are the site of development of lymphocytes and the secondary organs host cells which have been derived in the bone marrow and thymus but have migrated into the secondary structures (lymph nodes and spleen) to carry out their defense functions.

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173
Q

The two broad categories of specific immune responses are antibody-mediated and humoral.

T/F

A

F

This statement is false. The two broad categories of specific immune responses are cellular immunity, which is mediated by T cells, and humoral immunity, which is mediated by B cells. Humoral immunity and antibody-mediated immunity are the same thing

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174
Q

Which of the following statements regarding B cells is NOT correct?

A) B cells can act as antigen-presenting cells

B) B cells can secrete antibodies

C) Activation of B cells requires class 1 MHC proteins

D) B ell activation is stimulated by cytokines

E) B cells usually require helper T cells to be activated

A

C

B cell activation does not require MHC class I proteins. B cell activation is stimulated by certain cytokines, especially those released by activated helper T cells. Activated B cells secrete antibodies, but can also act as antigen-presenting cells.

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175
Q

B and T cells are preprogrammed to recognize specific antigens.

T/F

A

T

This statement is true. Each B cell has a receptor on its plasma membrane that recognizes a specific molecular conformation. Similarly, T cells have specific membrane-bound T cell receptors. B and T cells recognize only antigens that bind to these receptors.

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176
Q

In cell-mediated immune responses, immune cells directly kill antigen-bearing cells.

T/F

A

T

This statement is true. Cytotoxic T cells directly destroy antigen-bearing cells by perforating these cells and by causing them to undergo apoptosis.

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177
Q

Which of the following statements concerning immunoglobulin proteins produced by B cells is NOT correct?

A) They have a Y-shape structure with light chains and heavy chains

B) They have constant (conserved) and variable ends in their protein structure

C) They occur in a large variety in order to recognize and neutralize diverse infectious agents

D) They are found at all ages, although not uniformly, so that some may be added during fetal life, others during lactation and still others during later adult life

E) All immunoglobulin proteins produced by B cells are secreted

A

E

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178
Q

Antigens presented in association with class I MHC proteins are recognized by _______, while antigens presented in association with class II MHC are recognized by _______.

A) B cells; cytotoxic T cells

B) Helper T cells; cytotoxic T cells

C) B cells; helper T cells

D) Cytotoxic T cells; helper T cells

E) Helper T cells; B cells

A

D

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179
Q

Along with antigen presentation, additional stimulation for activation of helper T cells is the result of the release of ______ by antigen presenting cells.

A) Interleukin-1

B) Interleukin-2

C) Tumor necrosis factor

D) Interleukin-1 and tumor necrosis factor

E) Interleukin-1 and interleukin-2

A

D

Antigen presenting cells release IL-1 and TNF which provides stimulation for activation of helper T cells. This causes the T cell to secrete and express receptors for IL-2. The IL-2 then stimulates the helper T cell to proliferate.

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180
Q

Which of the following statements concerning NK cells is NOT correct?

A) They are a distinct class of lymphocytes

B) The are “natural killer” cells

C) They are functionally similar to cytotoxic T-cells

D) They attack cancer cells and virus infected cells

E) They are antigen specific and must recognize an antigen on a target cell before attacking it

A

E

NK abbreviation stands for “natural killer” cells. These cells are a distinct class of lymphocytes which act similar to Cytotoxic T-cells. They attack many cancer cells and virus-infected cells but in contrast to Cytotoxic T-cells, do not need to recognize an antigen on the surface of a target cell before attacking it.

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181
Q

Which of the following statements regarding antibody types is correct?

A) IgD and IgM are the most abundant antibodies produced

B) IgG antibodies participate in allergic reaction

C) IgA antibodies are commonly found in secretions

D) IgE antibodies have a function that remains unclear

A

C

IgA antibodies are found in secretions. IgG and IgM antibodies are the most abundant antibodies. IgE antibodies participate in allergic reactions. IgD antibodies have a function that remains unclear.

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182
Q

Which of the following statements does NOT correctly describe antibodies?

A) Antibodies are secreted by plasma cells

B) Antibodies protect against bacteria and viruses by binding to them and presenting them to phagocytes

C) Antibodies protect against viruses by binding to them and neutralizing them

D) Antibodies activate complement

E) Antibodies protect against bacteria by binding to them and perforating them

A

E

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183
Q

Cytotoxic T cells destroy viral infected body cells by phagocytosis.

T/F

A

F

This statement is false. Cytotoxic T cells do not act as phagocytes. They destroy antigen-bearing cells by releasing the contents of their secretory vesicles (through exocytosis) into the space between it and the target cell to which it is attached. The vesicle contains perforin, which inserts into the membrane of the target cell causing it to lyse. Cytotoxic T cells also release molecules that cause cells to undergo apoptosis.

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184
Q

Fever is part of the acute phase response to disease, and it is considered beneficial to the immune system.

T/F

A

T

This statement is true. Fever is part of the acute phase response. The increase in body temperature enhances many immune responses.

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185
Q

Which of the following statements concerning the disease AIDS is NOT correct?

A) It is called Acquired Immune Deficiency Syndrome

B) It is a hereditary disorder

C) It is a viral disease caused by the HIV virus

D) It can be transmitted from mother to fetus

E) The infected individuals lose their reserves of T-cells, particularly the helper T-cells

A

B

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186
Q

Antibiotics are all synthetic compounds that interfere with some essential function of the infectious microbes (such as bacteria).

T/F

A

F

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187
Q

Which of the following cells play major roles in rejection of a tissue graft (such as a kidney transplant from an unrelated donor)?

A) Cytotoxic and Helper T- cells

B) Plasma cells

C) Macrophages

D) B-cells

E) NK cells

A

A

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188
Q

Antibodies against both type A and type B antigens are found in the plasma of a person whose blood type is ________.

A) Type A

B) Type B

C) Type AB

D) Type O

A

D

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189
Q

Which of the following people may suffer from a type of hemolytic anemia called “hemolytic disease of the newborn”?

A) An Rh+ fetus being carried by an Rh- mother.

B) An Rh- mother who is pregnant with an Rh+ fetus.

C) An Rh- fetus being carried by an Rh+ mother.

D) An Rh+ mother who is pregnant with an Rh- fetus.

E) An Rh- fetus who has an Rh+ father.

A

A

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190
Q

Autoimmune diseases are caused by production of certain inappropriate antibodies which recognize body proteins as non-self (foreign) and attack them causing tissue destruction and diseases.

T/F

A

T

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191
Q

Which of the following correctly matches a body fluid compartment with its approximate volume?

a) intracellular fluid: 40% of total body fluids
b) extracellular fluid: 20% of total male body mass
c) interstitial fluid: 20% of extracellular fluid
d) plasma: 20% of interstitial fluid
e) solids: 55% of total female body mass

A

A

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192
Q

Metabolic water contributes about half of the daily water gain.

T/F

A

F

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193
Q

Thirst may be stimulated by

  1. decreased flow of saliva.
  2. decreased blood pressure.
  3. decreased blood osmolarity.

a) 1 only
b) 2 only
c) 3 only
d) 1 and 2 are correct.
e) 1, 2, and 3 are correct.

A

D

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194
Q

Atrial natriuretic peptide helps to regulate the volume and osmolarity of body fluids by

a) stimulating the desire to drink fluids to quench thirst.
b) stimulating the secretion of aldosterone.
c) increasing urinary excretion of sodium and chloride ions accompanied by water.
d) increasing the permeability of the collecting ducts to water.
e) increasing urinary reabsorption of sodium and chloride ions accompanied by water.

A

C

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195
Q

Decreased blood sodium levels may cause cells to swell because of decreased interstitial fluid osmolarity

T/F

A

T

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196
Q

All of the following are functions of electrolytes in the body EXCEPT

a) control osmosis of water between fluid compartments.
b) act as enzymes in some metabolic pathways.
c) serve as enzyme cofactors.
d) help maintain acid-base balance.
e) carry electrical current.

A

B

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197
Q

Because of the involvement of carbon dioxide in the carbonic acid-bicarbonate buffer system, this buffer system provides protection against pH changes due to respiratory problems that lead to an excess or shortage of carbon dioxide.

T/F

A

F

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198
Q

Respiratory acidosis

a) may be caused by inadequate inhalation of carbon dioxide.
b) may be corrected by hyperventilation.
c) is due to a increase in blood bicarbonate levels.
d) is most commonly caused by excessive vomiting.
e) may be a side effect of diabetic ketosis.

A

B

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199
Q

Depression of the central nervous system is one of the major physiological effects of acidosis.

T/F

A

T

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200
Q

An infant with severe diarrhea and vomiting may experience greater problems with fluid, electrolyte, and acid-base balance than an adult with the same disorder because

a) more of an infant’s body mass is water.
b) infants have a slower metabolic rate.
c) the less developed kidney function in infants causes increased excretion of acid.
d) body surface area: body volume is less in infants than in adults.
e) newborns have a tendency toward metabolic alkalosis to start with.

A

A

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201
Q
  1. What change in renal regulation of H+ would help compensate for a metabolic acidosis?

A. an increase in the production of new plasma HCO3-
B. reabsorption of H+ from the tubular fluid
C. an increase in the urinary pH
D. a decrease in the filtered load of H+
E. a decrease in the amount of H+ secreted in the proximal tubule

A

A

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202
Q

Water and NaCl reabsorbed from the loop of Henle directly re-enter what blood vessels?

A.  efferent arterioles 
B.  afferent arterioles 
C.  collecting ducts 
D.  cortical peritubular capillaries 
E.  vasa recta
A

E

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203
Q

Which of the following statements is NOT correct?

a) The female urethra extends from the internal to external urethral orifices, and is significantly longer then the male urethra
b) The male urethra consist of two segments
c) Both the male and the female urethra contain transitional epithelium, simple cuboidal (keratinized), stratified columnar epithelium, and stratified squamous epithelium.
d) All of the statements are correct.
e) None of the statements are correct.

A

E

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204
Q

All of the following might be observed in a freshly voided normal urine sample EXCEPT

a) amber color.
b) transparency.
c) ammonia odor
d) pH 6.0
e) specific gravity 1.020.

A

C

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205
Q

The action of symporters which actively reabsorb ions from the tubular fluid in the ___________________ lowers the osmolarity of the tubular fluid

a) glomerulus.
b) proximal convoluted tubules.
c) descending limb of the nephron loop.
d) thick segment of the ascending nephron loop
e) collecting ducts.

A

D

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206
Q

A large number of sodium ions and glucose molecules may be reabsorbed through

a) sodium-glucose symporters in the proximal convoluted tubules.
b) sodium-glucose antiporters in the nephron loop.
c) sodium-glucose symporters in the collecting duct
d) sodium-hydrogen ion antiporters in the late distal convoluted tubule.
e) sodium-glucose antiporters in the proximal convoluted tubules

A

A

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207
Q

Glomerular filtration rate is decreased by all of the following EXCEPT

a) increased production of angiotensin II.
b) increased secretion of atrial natriuretic peptide.
c) constriction of smooth muscle fibers in afferent arterioles.
d) dilation of smooth muscle fibers in efferent arterioles
e) increased activity of renal sympathetic nerves.

A

B

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208
Q

Which of the following equations is CORRECT?

a) NFP = GBHP + CHP – BCOP
b) NFP = GBHP – CHP + BCOP
c) NFP = GBHP + CHP + BCOP
d) NFP = GBHP – CHP – BCOP
e) NFP = GBHP – BCOP

A

D

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209
Q

The glomerular filtrate contains a lower concentration of____ than does blood plasma.

a) albumin
b) glucose
c) water
d) sodium
e) urea

A

A

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210
Q

Juxtamedullary nephrons

a) make up about 80-85% of the nephrons within the kidney.
b) allows excretion of very dilute or concentrated urine.
c) have renal corpuscles located in the outer portion of the renal cortex.
d) have very short nephron loops.
e) have very thick descending nephron loops.

A

B

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211
Q

All of the following are wastes removed by the kidneys EXCEPT

a) urea.
b) bilirubin.
c) creatinine.
d) drugs.
e) water.

A

E

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212
Q

T/F

The primary difference between active and passive immunity is that in active immunity, antibodies are produced in response to the presence of an antigen, while in passive immunity; pre-formed antibodies are provided from one person to another.

A

T

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213
Q

Which of the following negatively affects the immune system?

a) smoking
b) lack of sleep
c) sedentary lifestyle
d) stress
e) all of these choices

A

E

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214
Q

The lack of reactivity to the body’s own proteins is known as:

a) positive selection
b) self-recognition
c) deletion
d) self-tolerance
e) anergy

A

D

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215
Q

Which antibody crosses the placenta?

a) IgA
b) IgD
c) IgE
d) IgG
e) IgM

A

D

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216
Q

Which is not true of the cytokines?

a) are small proteins
b) can help regulate adaptive immune responses
c) can influence cell growth
d) are secreted by erythrocytes
e) include the interleukins secreted by T cells

A

D

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217
Q

Which of the following is not a characteristic of the major histocompatibility complex (MHC) antigens?

a) are also called human leukocyte antigens
b) are a major reason for tissue rejection in transplantation surgery
c) mark each body cell surface except the white blood cells
d) primary function is to aid the T cells in recognizing foreign antigens
e) there are two major types

A

C

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218
Q

When T and B cells develop the ability to carry out adaptive immune responses, this is known as

a) lymphology
b) immunocompetence
c) memory
d) specificity
e) genetic recombination

A

B

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219
Q

Which is not a sign or symptom of inflammation?

a) contracture of tissue
b) triggering of nociceptors
c) erythema
d) loss of function
e) localized increase in tissue size

A

A

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220
Q

Which is not true in the comparison of natural killer (NK) cells and phagocytes?

a) macrophages are major phagocytes
b) NK cells identify B and T cells
c) macrophages get rid of cellular debris
d) NK cells secrete a substance that creates holes in the membrane of a microbe
e) macrophages can remain in a tissue or travel throughout the body

A

B

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221
Q

Which of the following is not part of the second line of defense/internal defenses?

a) phagocytes
b) erythrocytes
c) interferons
d) natural killer cells
e) antimicrobial proteins

A

B

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222
Q

Which is not true in the comparison of natural killer (NK) cells and phagocytes?

a) macrophages are major phagocytes
b) NK cells identify B and T cells
c) macrophages get rid of cellular debris
d) NK cells secrete a substance that creates holes in the membrane of a microbe
e) macrophages can remain in a tissue or travel throughout the body

A

A

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223
Q

All of the following are true of lymphatic vessels except:

a) both lower extremities eventually drain into the thoracic duct
b) the subclavian trunks drain the upper appendages
c) the right bronchomediastinal trunk, right subclavian trunk, and right jugular trunk drain into the right lymphatic duct
d) the intestinal trunk drains into the right lymphatic duct
e) the left bronchomediastinal trunk, left subclavian trunk, and left jugular trunk drain into the thoracic duct

A

D

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224
Q

Which of the following is not true of lymph and the lymphatic system?

a) it returns excess interstitial fluid to the blood
b) it responds to certain microbes and abnormal cells
c) lymph is found in the intracellular fluid
d) it carries fat-soluble vitamins
e) lymph is a relatively clear liquid

A

C

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225
Q

Primary spermatocytes go through meiosis I; the two haploid cells formed during meiosis I are called

a) Spermatogonia
b) Tertiary spermatocytes
c) Secondary spermatocytes
d) Spermatids
e) Spermatozoa

A

C

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226
Q

The acrosome of a sperm contains the mitochondria needed for ATP production

T/F

A

F

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227
Q

Sperm are transported within the spermatic cord through

a) pampinform plexux
b) epididymis.
c) ductus deferens.
d) rete testis and epididymis are both correct.
e) rete testis, epididymis, and ductus deferens are all correct.

A

C

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228
Q

__________ stimulates the interstitial cells of the testes to secrete __________.

A. Luteinizing hormone (LH); testosterone
B. Luteinizing hormone (LH); estrogen
C. Luteinizing hormone (LH); androgen-binding protein (ABP)
D. Follicle-stimulating hormone (FSH); androgen-binding protein (ABP)
E. Gonadotropin-releasing hormone (GnRH); LH

A

A

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229
Q

All of the following structures are considered to be part of the spermatic cord EXCEPT the

a) pampiniform plexus.
b) ductus deferens.
c) cremaster muscle.
d) prostatic urethra.
e) lymphatic vessels.

A

D

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230
Q

The prostate secretes all of the following EXCEPT

a) sperm.
b) citric acid (ATP production)
c) proteolytic enzymes (break up clotted sperm)
d) seminalplasmin (antibiotics)

A

A

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231
Q

During oogenesis, the first haploid stage is the

a) oogonium
b) primary oocyte.
c) secondary oocyte.
d) ovum.
e) zygote.

A

C

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232
Q

10) Which of the following statements about the uterus is NOT correct?

a) The uterus is anterior to the urinary bladder.
b) The fundus is the portion of the uterus that is superior to the uterine tubes.
c) The isthmus is located between the body of the uterus and the cervix.
d) The internal os is the superior opening of the cervical canal.
e) The cervix projects inferiorly and posteriorly.

A

A

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233
Q

the __________ of the uterus is part of the visceral peritoneum.

a) stratum functionalis.
b) stratum basalis
c) perimetrium
d) myometrium
e) endometrium

A

C

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234
Q

The extensive blood supply of the uterus is essential to support regrowth of a new stratum basalis following menstruation.

T/F

A

F

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235
Q

Shedding of the endometrial lining occurs:

A. because ovulation disrupts the growing follicle.
B. because of an increase in the level of FSH.
C. a day after the LH surge.
D. as a result of a fall in plasma levels of estrogen and progesterone.
E. because the non-dominant follicles undergo atresia.

A

D

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236
Q

The secretory phase of the uterine cycle is associated with

a) increased secretion of progesterone and formation of the corpus albicans.
b) increased secretion of progesterone and formation of the corpus luteum.
c) increased secretion of luteinizing hormone and rupture of the mature follicle.
d) increased secretion of estrogen and maturation of the secondary follicle.
e) increased secretion of follicle stimulating hormone and ovulation.

A

B

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237
Q

Fertilization in humans generally occurs in the

a) uterus.
b) ovary.
c) uterine tube.
d) cervix.
e) fimbriae.

A

C

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238
Q

A morula is a solid sphere of cells about the size of the original zygote, and still surrounded by the zona pellucida

T/F

A

T

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239
Q

The ____________ supplies nutrients to the embryo and is the source of blood cells during early embryonic development

a) trophoblast
b) hypoblast
c) epiblast
d) bilaminary embryonic disc
e) yolk sac

A

E

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240
Q

The muscles, bones, other connective tissues, and the peritoneum are all derived from the endoderm

T/F

A

F

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241
Q

The stages of labor are; dilation, expulsion and placental

T/F

A

T

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242
Q

The neural plate, neural folds, and neural tube form through the process of

a) gastrulation.
b) neurulation.
c) invagination.
d) induction.
e) somatization.

A

B

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243
Q

Which of the following is a sac filled with fluid that acts as a shock absorber, regulates temperature, and can help prevent the fetus from drying out?

a. yolk sac
b. allantois
c. amniotic sac
d. chorionic villus
e. none of the above

A

C

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244
Q

The placenta forms from the chorionic villi of the mother and the decidua basalis of the embryonic endoderm.

T/F

A

F

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245
Q

. Which of the following are functions of the hormone relaxin? This is a multiple-multiple; choose all that apply.

a. help increase the flexibility of the pubic symphysis during labor
b. help dilate the cervix during labor
c. stimulate the mammary glands to relax during the milk-let-down reflex
d. stimulate uterine contractions during true labor
e. stimulate ovulation along with the LH surge

A

A, B

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246
Q

Progesterone is required during pregnancy to

a) stimulate the corpus luteum.
b) ensure relaxation of the uterine myometrium.
c) increase the flexibility of the pubic symphysis.
d) decrease glucose usage by the mother while making it more available to the fetus.
e) help establish the timing of labor and delivery.

A

B

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247
Q

The shift of blood flow from the uterus to the muscles and skin during exercise may result in an inadequate blood supply to the placenta.

T/F

A

F

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248
Q

False labor exhibits which of the following symptoms?

a) contractions at regular intervals.
b) pain at irregular intervals that does not intensify.
c) discharge of blood-containing mucus into the cervical canal.
d) alteration of pain by walking.
e) cervical dilation.

A

B

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249
Q

Closure of the ductus arteriosus requires

a) closure of the foramen ovale.
b) functioning of the lungs.
c) decreasing blood oxygen levels at birth.
d) ligation of the umbilical cord.
e) collapse of the ductus venosus.

A

B

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250
Q

Prolactin stimulates contraction of myoepithelial cells in the breast to cause milk ejection.

T/F

A

F

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251
Q

Which of the following statements concerning the process of differentiation of the reproductive organs is correct?

A )Androgens direct the development of the male genitalia and reproductive tract

B) In male embryos, the Wolffian ducts will regress spontaneously (i.e. without intervening factors)

C) Androgens direct the development of male reproductive organs in genetic males and estrogens direct the development of female reproductive organs in genetic females

D) SRY gene is necessary for the development of the female reproductive system

A

A

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252
Q

For every primary spermatocyte, two sperm bearing an X chromosome and two sperm bearing a Y chromosome will be produced.

T/F

A

T

This statement is true. In mammals, one half of the sperm produced during meiosis contain an X chromosome and one half of the sperm produced during meiosis contain a Y chromosome.

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253
Q

In the testis, Leydig cells

A) Synthesize and secrete the androgen hormone testosterone

B) Are responsible for the secretion of hormone inhibin

C) Aid in sperm formation and form androgen binding protein (ABP)

D) Help in storage and biochemical maturation of the sperm

A

A

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254
Q

Sertoli cells

A) Are found in the space between the seminiferous tubules

B) Are responsible for the secretion of hormone testosterone

C) Aid in sperm formation and form androgen binding protein (ABP)

D) Enable the sperm to become motile

E) Give the sperm their ability to fertilize the egg

A

C

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255
Q

Which of the following statements is NOT correct?

A) Spermatogenesis occurs primarily from puberty until death

B) Meiotic divisions of gametogenesis produce cells with 23 chromosomes

C) Oogenesis lasts only from puberty until menopause

D) A female fetus has already begun mitotic cell division for gametogenesis

A

C

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256
Q

Which of the following structures aids in transport of sperm through the male reproductive tract during ejaculation?

A) Seminal vesicles and prostate

B) Vas deferens

C) Cowper’s (bulbourethral) glands

D) Urethra

E) Epididymides

A

B

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257
Q

In males, secretion of adrenal gland androgens stimulates the initial changes in secondary sex characteristics at puberty.

T/F

A

T

This statement is true. In males, these androgens cause the very early development of pubic and axillary hair, as well as the early stages of the pubertal growth spurt in concert with growth hormone and insulin-like growth factor I.

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258
Q

Meiosis always results in four functional daughter cells, each with one-half the number of chromosomes of the primordial germ cell.

T/F

A

F

259
Q

Which of the following statements concerning FSH is NOT correct?

A) FSH is necessary for the development of primary oocytes from oogonia

B) FSH stimulates growth of small-antral follicles to larger follicles

C) FSH secretion increases at the beginning of the follicular phase and then declines

D) FSH stimulates growth of granulosa cells

E) FSH stimulates secretion of estrogen

A

A

260
Q

Which of the following is NOT correct?

A) Granulosa cells produce estrogen with the help of thecal cells

B) High levels of progesterone in the blood stimulate LH release near the middle of the menstrual cycle

C) The corpus luteum secretes both progesterone and estrogen along with inhibin

D) FSH acts directly on granulosa cells

A

B

261
Q

The follicle, the corpus luteum, and the placenta all secrete hormones

T/F

A

T

262
Q

The most important hormone involved in inducing ovulation in the female is

A) Estrogen

B) Progesterone

C) FSH

D) LH

A

D

263
Q

The thickening of the endometrium of the uterus occurs as a result of the action of the __________ ovarian phase and occurs during the __________ uterine phase.

A) Follicular; menstrual

B) Follicular; proliferative

C) Follicular; secretory

D) Luteal; proliferative

E) Luteal; secretory

A

B

264
Q

The major and most important role of the female sex steroid hormone estrogen in the preparation for pregnancy is

A) Formation of the follicle

B) Growth of the corpus luteum

C) Proliferation and thickening of uterine endometrium

D) To stimulate secretory activity of uterine endometrial glands

E) To aid in sperm transport in the female tract

A

C

265
Q

Both sperm and egg have their own means of motility aiding their transport through the female tract.

T/F

A

F

266
Q

Which of the following statements regarding implantation and early development is correct?

A) The inner cell mass initiates the process of implantation

B) The inner cell mass will develop into the chorion

C) The trophoblast cells give rise to the amnion

D) Placental structure is a combination of embryonic and maternal tissue

A

A

267
Q

The hormones and/or hormonal changes that contribute to a successful birth are

A) An increase estrogen secretion

B) A decrease in oxytocin secretion

C) An increase in the progesterone:estrogen ratio

D) An increase in human chorionic gonadotropin secretion

A

A

268
Q

Suckling stimulus by the infant during nursing maintains lactation by

A) Increasing the secretion of oxytocin

B) Increasing the secretion of prolactin

C) Increasing the secretion of LH and FSH

D) Increasing the secretion of oxytocin and prolactin

E) Increasing secretion of estrogen and oxytocin

A

D

269
Q

Which of the following is NOT a function of the renal system?

A) Regulating the concentration of water and ions in the body

B) Excreting waste products

C) Secreting hormones

D) Producing glycogen

A

D

Feedback: The kidney doesn’t produce glycogen. However, it can perform gluconeogenesis to produce glucose. All of the other functions are typical renal functions.

270
Q

Which of the following structures composes the renal corpuscle?

A) Glomerular capillaries

B) Bowman’s capsule

C) Afferent arteriole

D) Glomerular capillaries and Bowman’s capsule

E) Afferent arteriole and Bowman’s capsule

A

D

Feedback: The renal corpuscle is composed of the glomerular capillaries which are surrounded by Bowman’s capsule. The afferent arteriole supplies blood to the glomerular capillaries, but it is not contained within the corpuscle.

271
Q

Which of the following is NOT a component of the filtration barrier within the renal corpuscle?

A) The endothelial cells that form the glomerular capillary

B) A thin layer of smooth muscle that surrounds the glomerular capillary

C) The epithelial cells that compose the visceral layer of Bowman’s capsule (podocyte cells)

D) The thin basement membrane that lies between the endothelial cells of the capillary and the epithelial cells of Bowman’s capsule

A

B

272
Q

Which of the following components of the filtration membrane form the filtration slits?

A) The capillary endothelial cells

B) The basement membrane

C) The podocyte cells

D) The capillary endothelial cells and the podocyte cells

A

C

Feedback: Filtration slits are the gaps that exist between the foot processes of the podocyte cells as they make contact with the basement membrane.

273
Q

The juxtaglomerular apparatus is composed of the

A) Juxtaglomerular cells

B) Macula densa

C) Mesangial cells

D) Juxtaglomerular cells and mesangial cells

E) Juxtaglomerular cells and macula densa

A

E

274
Q

Which of the following is NOT a basic renal process?

A) Glomerular filtration

B) Tubular reabsorption

C) Tubular secretion

D) Erythropoietin production

A

D

275
Q

Which of the following will cause an increase in the glomerular filtration rate?

A) Increasing the hydrostatic pressure of the blood

B) Increasing the colloid osmotic pressure of the blood

C) Increasing sympathetic nerve discharge to glomerular afferent arterioles

D) Efferent arteriole vasodilation

A

A

276
Q

The entire volume of plasma in the average person is filtered by the kidney approximately every 30 minutes

T/F

A

T

Feedback: This statement is true. Considering that the filtration rate is 125ml/min, it would take 24 minutes to filter the 3L of plasma in the average person.

277
Q

Which of the following is true about the reabsorption process of substances such as sodium, glucose and amino acids in the nephron?

A) It involves the Bowman’s capsule

B) It is restricted to the loop of Henle

C) It occurs mainly in the proximal convoluted tubules

D) It occurs mainly by osmosis

A

C

278
Q

In a healthy kidney, the rate of reabsorption of most organic nutrients (such as glucose) by the kidney is not actively regulated and is very efficient

T/F

A

T

Feedback: This statement is true. The kidneys reabsorb filtered organic nutrients such as monosaccharides and amino acids with great efficiency, and they are normally completely reabsorbed. This process occurs without active regulation

279
Q

In the process of reabsorption via transporters, when the binding sites on a renal transport protein become saturated

A) The transport maximum for that transporter has been reached

B) The substance being transported will begin to decrease in concentration in the urine

C) The rate of transport will increase in order to reabsorb even more of the substance being transported

D) The transporters will stop functioning

A

A

280
Q

Reabsorption of glucose in the kidney proximal tubules occurs by

A) Diffusion, depending on plasma glucose concentration

B) An active transport process that is linked to sodium reabsorption

C) An active transport process that is linked to amino acid transport

D) Active transport with no link to the transport of any other substance

A

B

281
Q

Which of the following substances is NOT commonly secreted by the renal tubules?

A) Sodium ions

B) Potassium ions

C) Drugs such as penicillin

D) Hydrogen ions

A

A

Feedback: Sodium is reabsorbed from the filtrate, but never secreted. Each of the others is commonly secreted into the filtrate.

282
Q

When the clearance of a molecule is less than the glomerular filtration rate (GFR) of that molecule, which of the following statements regarding that molecule is true?

A) It is filtered and is not subject to reabsorption or secretion

B) It is filtered and is partially reabsorbed

C) It is filtered and is partially secreted

D) It is totally filtered

A

B

Whenever the clearance of a substance is less than GFR, that substance must undergo reabsorption. If its clearance matched GFR, then it was neither reabsorbed nor secreted. If its clearance was greater than GFR, then it must have been secreted. There is no information to determine if it is totally filtered.

283
Q

Stretch receptors located in the bladder wall are important for micturition.

T/F

A

T

284
Q

In all nephron segments, the active transport of sodium by tubular cells is accomplished by the action of the Na+/K+ ATPase pump in the basolateral membrane.

T/F

A

T

285
Q

Movement of water out of the collecting ducts takes place by bulk flow.

T/F

A

F

286
Q

Which of the following is NOT associated with the increase in hypoosmotic urine production in persons with diabetes insipidus?

A) Failure of the posterior pituitary to secrete vasopressin

B) A blood glucose concentration that exceeds transport maximum in the nephron resulting in glucose, and thus water, remaining in the urine

C) The inability of the kidneys to respond to vasopressin

D) The inability of the kidneys to respond to ADH

A

B

287
Q

Which of the following does NOT contribute to the hypertonic medullary interstitium?

A) Solute reabsorption in the ascending limb of the loop of Henle

B) Sodium reabsorption in the distal tubule

C) Urea reabsorption from the proximal tubule

D) Urea recycling between the loop of Henle and the collecting duct

A

C

288
Q

Which of the following is a hormone formed in the blood as a result of converting a non-functional precursor protein into a functional protein which causes vasoconstriction, resulting in increased arterial pressure?

A) Renin

B) Aldosterone

C) Angiotensin

D) Vasopressin

A

C

289
Q

The hormone that most directly influences Na+ reabsorption in the collecting duct is

A) Aldosterone

B) Angiotensin

C) Renin

D) Vasopressin

A

A

290
Q

Which of the following drugs would be most effective in treating hypertension?

A) An alpha-adrenergic agonist

B) An ADH agonist

C) An angiotensin-converting enzyme inhibitor

D) A stimulator of aldosterone synthesis

A

C

291
Q

Which of the following hormones would act on the kidney collecting ducts to increase water reabsorption as would occur during dehydration (increased plasma osmolarity)?

A) Aldosterone

B) Angiotensin

C) Renin

D) ADH (vasopressin)

E) ANP (atrial natriuretic peptide)

A

D

292
Q

Which of the following statements regarding renal handling of water by the kidneys is correct?

A) In the absence of vasopressin, urine is isoosmotic with plasma.

B) In the absence of vasopressin, water cannot be reabsorbed in the proximal tubules.

C) In the absence of vasopressin, the cortical collecting ducts have very low permeability to water.

D) In the absence of vasopressin, the distal tubules secrete water.

A

C

293
Q

The loss of 0.5 liter of sweat will provoke a greater sense of thirst than the loss of the same volume of blood plasma.

T/F

A

T

294
Q

Despite the presence of the Na+/K+ ATPase pumps in the basolateral membrane of most nephron tubules, the secretion of K+ into the lumen is limited to the cortical collecting duct cells because only these cells have luminal K+ leak channels.

T/F

A

T

295
Q

Much like small organic nutrients, calcium reabsorption by the kidney occurs in the proximal tubule and is not subject to regulation.

T/F

A

F

This statement is false. While the kidney readily reabsorbs about 60% of the filtered calcium, the remainder of calcium reabsorption is under the control of parathyroid hormone (PTH).

296
Q

Which of the following substances is NOT involved in the buffering functions of the kidney?

.
A) Oxalate

B) Phosphate

C) Ammonia

D) Bicarbonate

A

A

Oxalate is not a known kidney buffer. Bicarbonate is the most effective buffering agent in the plasma and in the kidney. Phosphate also acts as a buffer in the urine and accepts hydrogen ions. Ammonia production is also important when acidity in the filtrate is increased for a long period.

297
Q

Which of the following statements regarding renal regulation of hydrogen-ion concentration by the kidneys is true?

A) Renal regulation of extracellular H+ concentration is dependent upon regulating the amount of hydrogen ion filtered by the kidneys.

B) Renal regulation of extracellular H+ concentration is dependent upon regulating the amount of hydroxides secreted by the kidneys

C) Renal regulation of extracellular H+ concentration is accomplished in part by regulating the amount of bicarbonate ion excreted by the kidneys

D) Most of the H+ excreted in the urine is bound to bicarbonate

A

C

298
Q

The presence of this substance in the urine is considered a sign of kidney disease or kidney disorder.

A) Urea

B) Electrolytes (e.g. sodium and potassium)

C) Plasma proteins (e.g., albumins)

D) Glucose

A

C

299
Q

The kidneys help control blood pressure by the secretion of

A.erythropoietin

B.angiotensin

C.aldosterone

D.renin

A

D

300
Q

A function of the kidney is to

A.remove nutrients from the blood

B.remove microorganisms from the blood

C.regulate blood ionic composition

D.add vitamins and rare ions to the blood

A

C

301
Q

The kidneys secrete the hormone erythropoietin, which functions to:

A.regulate blood pressure
B.activate vitamin D
C.concentrate salt in the nephron
D.control the rate of red blood cell production

A

D

302
Q

Which of the following structures are found in the renal cortex?

A.distal convoluted tubules
B.renal columns
C.collecting ducts
D.minor calyces

A

A

303
Q

The renal pelvis

A.is formed by the union of minor calyces
B.channels urine towards the renal pyramids
C.contains collecting tubules
D.drains into the ureter

A

D

304
Q

The outer layer of the three layers of tissue that surround the kidney is the

A.renal fascia
B.adipose capsule
C.renal capsule
D.peritoneum

A

A

305
Q

The innermost layer of the three layers of tissue that protect the kidney is the

A.renal fascia
B.adipose capsule
C.renal capsule
D.peritoneum

A

C

306
Q

The renal papillae contain papillary ducts which empty into the

A.minor calyces
B.ureters
C.renal pelvis
D.urethra

A

A

307
Q

Which of the following accurately represents the pathway of fluid through a juxtamedullary nephron?

A. proximal convoluted tubule, distal convoluted tubule, descending loop of Henle, ascending loop of Henle
B. proximal convoluted tubule, descending loop of Henle, ascending loop of Henle, distal convoluted tubule
C. distal convoluted tubule, descending loop of Henle, ascending loop of Henle, proximal convoluted tubule
D. distal convoluted tubule, ascending loop of Henle, descending loop of Henle, proximal convoluted tubule

A

B

308
Q

The nephron has two parts. They are the

A.glomerulus and renal tubule
B.capsule and loop of Henle
C.glomerulus and peritubular capillaries
D.renal corpuscle and renal tubule

A

D

309
Q

The visceral layer of Bowman’s capsule is covered with specialized cells called:

A.podocytes
B.fenestrations
C.pedicels
D.slits

A

A

310
Q

Externally, the kidney is protected and supported by connective tissue and

A.mesentery
B.adipose tissue
C.serous fluid
D.cartilage

A

B

311
Q

Renal blood pressure remains fairly constant due to the function of the

A.loop of Henle
B.Bowman’s capsule
C.fenestra
D.juxtaglomerular apparatus

A

D

312
Q

In cortical nephrons, the

A.renal corpuscle lies in the outer portion of the renal cortex
B.loop of Henle penetrates far down into the medulla
C.glomerulus is larger then the juxtamedullary nephron glomeruli
D.proximal convoluted tubules are very short

A

A

313
Q

The proximal convoluted tubule is made up of

A.simple squamous cells
B.columnar cells covered with cilia
C.podocytes
D.cuboidal cells with many microvilli

A

D

314
Q

Fenestrations are associated with the

A.loop of Henle
B.Bowman’s capsule
C.collecting duct
D.glomerulus

A

D

315
Q

Filtration of blood

A.occurs in the glomerulus
B.occurs in the renal tubules
C.increases systemic blood pressure
D.causes H+ and K+ to concentrate in blood

A

A

316
Q

Which of the following molecules cannot pass the filtration membranes in the kidneys?

A.sodium ions
B.glucose
C.amino acids
D.large proteins

A

D

317
Q

Glomerular filtrate is produced as a result of

A.reabsorption
B.blood hydrostatic pressure
C.tubular secretion
D.facilitated diffusion

A

B

318
Q

Normally, net filtration pressure in the kidney is about

A.5 mm Hg
B.10 mm Hg
C.50 mm Hg, the same as in capillaries
D.80 mm Hg, the same as diastolic blood pressure

A

B

319
Q

In the process of renal autoregulation, when the juxtaglomerular apparatus secretes less vasoconstrictor substance,

A.the afferent arterioles dilate, increasing glomerular filtration rate
B.the efferent arterioles dilate, allowing blood to flow through the kidney faster
C.the loop of Henle reabsorbs more sodium and chloride ions
D.the collecting tubule reabsorbs less water

A

A

320
Q

Which pressure is the primary pressure driving glomerular filtration?

A.glomerular blood hydrostatic pressure
B.capsular hydrostatic pressure
C.blood colloid osmotic pressure
D.capsular colloid osmotic pressure

A

A

321
Q

Sodium is moved out of the cells of the proximal convoluted tubule and into the interstitial fluid by the process of

A.diffusion
B.facilitated diffusion
C.active transport
D.osmosis

A

C

322
Q

Reabsorption is the movement of molecules from the _____ into the _____ .

A.glomerulus, renal tubule
B.tissues, distal convoluted tubule
C.renal tubules, peritubular capillaries
D.proximal convoluted tubule, distal convoluted tubule

A

C

323
Q

Very little water reabsorption occurs in the

A.thick ascending loop of Henle
B.proximal convoluted tubule
C.thin descending loop of Henle
D.collecting ducts

A

A

324
Q

Sodium ions move through the apical membranes of principal cells of the collecting duct by

A.secondary active transport
B.osmosis
C.sodium pumps
D.diffusion

A

D

325
Q

Chloride ions are actively reabsorbed from the

A.collecting tubule
B.glomerulus
C.proximal convoluted tubule
D.thick ascending limb of the loop of Henle

A

D

326
Q

Potassium ions are actively secreted into the tubular fluid of the

A.distal convoluted tubule
B.loop of Henle
C.peritubular capillaries
D.ascending limb

A

A

327
Q

Most reabsorption occurs in the

A.loop of Henle
B.proximal convoluted tubule
C.Bowman’s capsule
D.distal convoluted tubule

A

B

328
Q

Which of the following chemicals is an enzyme secreted by the juxtaglomerular apparatus?

A.aldosterone
B.antidiuretic hormone
C.atrial naturetic peptide
D.renin

A

D

329
Q

Glucose enters the proximal convoluted tubule cells by _____ and leaves the cell into the interstitial fluid by _____.

A.simple diffusion, active transport
B.facilitated diffusion, simple diffusion
C.sodium ion-glucose symporters, facilitated diffusion
D.primary active transport, sodium ion-glucose symporters

A

C

330
Q

The main region of the kidney tubule that is impermeable to water is the

A.collecting duct
B.thin descending limb of the loop of Henle
C.proximal convoluted tubule
D.thick ascending limb of the loop of Henle

A

D

331
Q

The main regulator of facultative water reabsorption is

A.antidiuretic hormone
B.aldosterone
C.renin
D.angiotensin

A

A

332
Q

Which of the following occurs by the action of Na+ symporters in the apical membranes of tubule cells?

A.reabsorption of hydrogen ions by proximal convoluted tubule cells

B.reabsorption of amino acids by proximal convoluted tubule cells

C.secretion of hydrogen ions by intercalated cells

D.both reabsorption of glucose by proximal convoluted tubule cells and reabsorption of amino acids by proximal convoluted tubule cells

A

D

333
Q

Ions, but not water, are reabsorbed from the tubular fluid in the ascending loop of Henle. Therefore, the osmolarity of the fluid entering the distal convoluted tubule is

A.less than pure water
B.greater than blood
C.greater than the glomerular filtrate
D.less than blood

A

D

334
Q

In renal interstitial fluid

A.sodium chloride has the same concentration from cortex to medulla
B.sodium chloride concentration decreases from cortex to medulla
C.water concentration increases from cortex to medulla
D.sodium chloride concentration increases from cortex to medulla

A

D

335
Q

Increased sodium and chloride ion concentrations in the interstitial fluid of the renal medulla is the result of

A.renin secretion
B.tubular secretion
C.reabsorption of glucose
D.countercurrent mechanism

A

D

336
Q

The most important solutes that contribute to the high osmolarity of the interstitial fluid in the renal medulla are

A.potassium ions, hydrogen ions, and water
B.sodium ions, chloride ions, and urea
C.glucose, proteins, and calcium ions
D.renin, aldosterone, and angiotensin

A

B

337
Q

Urine contains:

A.waste products of digestion
B.waste products of metabolism
C.only water
D.only water and proteins

A

B

338
Q

Creatinine is produced by the breakdown of creatine phosphate in the skeletal muscles. It is useful for determining glomerular filtration rate (GFR) because it is

A.filtered but not reabsorbed or secreted
B.filtered and extensively secreted but not reabsorbed
C.filtered and secreted to a very small extent
D.secreted but not filtered or reabsorbed

A

A

339
Q

The color of urine is due to the presence of a chemical called

A.urochrome
B.urea
C.creatinine
D.inulin

A

A

340
Q

Urine leaves the urinary bladder through the

A.urethra
B.collecting duct
C.ureter
D.renal vein

A

A

341
Q

The external opening of the urinary system is the

A.anus
B.urethra
C.external urethral orifice
D.vaginal orifice

A

C

342
Q

Urine reaches the urinary bladder through the

A.urethra
B.external urethral orifice
C.ureter
D.renal vein

A

C

343
Q

During the micturition reflex ___________.

A.sympathetic fibers conduct impulses from the brain that cause contraction of the external urethral sphincter

B.sympathetic fibers conduct impulses from the spinal cord that cause relaxation of the external urethral sphincter

C.parasympathetic fibers conduct impulses from the spinal cord that cause relaxation of the detrusor muscle

D.parasympathetic fibers conduct impulses from the spinal cord that cause contraction of the detrusor muscle

A

D

344
Q

The urinary bladder in the female lies inferior to the:

A.small intestines
B.uterus
C.rectum
D.vagina

A

B

345
Q

Which waste management system binds excess hydrogen ions and thus prevents an increase in the acidity of body fluids?

A.lungs
B.blood
C.body buffers
D.liver

A

C

346
Q

In the embryo, the first kidney to form is the

A.mesonephros
B.pronephros
C.metanephros
D.urogenital diaphragm

A

B

347
Q

The normal kidneys are only about _____ as effective at the age of 70 as they are at the age of 40.

A.10 percent
B.25 percent
C.50 percent
D.75 percent

A

C

348
Q

A patient has symptoms that include painful, frequent urination, and low back pain. Further examination reveals inflammation of the mucosa and submucosa of the urinary bladder. The patient has

A.polycystic disease
B.cystitis
C.bilirubinuria
D.gall stones

A

B

349
Q

A patient is brought to the emergency room. Blood evaluation reveals high levels of creatinine, urea, uric acid, and potassium. Family members report failure to urinate, even though the patient consumed a fairly large quantity of water during the day. The patient is experiencing

A.pyelitis
B.urinary tract infection
C.renal failure
D.horseshoe kidney

A

C

350
Q

The largest volume of body fluid is located

A.in plasma
B.in lymph
C.within cells
D.between cells

A

C

351
Q

Reabsorption of sodium from the tubules of the nephron establishes an osmotic gradient that causes _____ to move back into the blood.

A.salt
B.water
C.magnesium
D.calcium

A

B

352
Q

The cerebrospinal fluid in the brain is classified as

A.intracellular fluid
B.lymph
C.extracellular fluid
D.plasma

A

C

353
Q

Bone, DNA, RNA, ATP, and cell membranes all have one thing in common. They all contain _____.

A.sulfur
B.Calcium
C.phosphate
D.magnesium

A

C

354
Q

Intracellular fluid has

A.a higher concentration of potassium than interstitial fluid
B.a lower concentration of protein anions than plasma
C.a higher concentration of bicarbonate than plasma
D.approximately the same concentrations of sodium, chloride, and potassium as plasma

A

A

355
Q

Parathyroid hormone

A.is released when blood calcium level rises
B.stimulates osteoblasts and inhibits osteoclasts
C.causes the cells of the nephron to reabsorb phosphate
D.causes renal tubule cells to reabsorb calcium

A

D

356
Q

Levels of which of the following are regulated by aldosterone?

A.carbonic acid
B.glucose
C.magnesium
D.sodium

A

D

357
Q

Electrolytes

A.dissociate into anions and cations
B.generally have covalent bonds
C.include glucose, urea, and creatine
D.are usually organic compounds

A

A

358
Q

Which of the following is true concerning sodium ions?

A.They represent about 90 percent of extracellular anions
B.They combine with chloride ions in gastric glands to form hydrochloric acid
C.They are necessary for generation of action potentials
D.Excess ions are stored by the kidneys

A

C

359
Q

Which one of the following chemicals is a not an electrolyte?

A.calcium phosphate
B.potassium chloride
C.sodium bicarbonate
D.glucose

A

D

360
Q

The most abundant cation in plasma is _______.

A.phosphate
B.potassium
C.sodium
D.chloride

A

C

361
Q

ower than normal blood concentration of sodium is

A.called hypernatremia
B.characterized by muscular weakness, tachycardia, and dizziness
C.characterized by thirst, restlessness, agitation, and coma
D.due to the fact that most people do not consume enough sodium

A

B

362
Q

A patient whose blood pH is 7.5, whose concentration of HCO3− in arterial blood is 25 mEq/liter, and whose partial pressure of CO2 is 32 mm Hg in arterial blood is experiencing ________alkalosis?

A.uncompensated metabolic
B.compensated metabolic
C.uncompensated respiratory
D.compensated respiratory

A

C

363
Q

Hyperventilation (breathing in and out more air than normal) during a panic attack causes an increase in blood ________.

A.pH
B.H+
C.partial pressure of CO2
D.partial pressure of CO2 and H+

A

A

364
Q

The most abundant buffer system inside body cells and in plasma is the

A.carbonic acid buffer system
B.phosphate buffer system
C.sodium bicarbonate buffer system
D.protein buffer system

A

D

365
Q

The only way the body can get rid of the huge acid load produced by metabolic reactions is to

A.increase the concentration of bicarbonate ions
B.breathe faster and more deeply
C.excrete hydrogen ions in the urine
D.increase the concentration of proteins in the plasma

A

C

366
Q

The metabolic rate of infants is about _______ as that of adults.

A.the same
B.double
C.triple
D.quadruple

A

B

367
Q

The major physiological effect of acidosis is ______. The major physiological of alkalosis is ______.

A.depression of the CNS; depression of the CNS
B.depression of the CNS; overexcitability of the CNS
C.overexcitability of the CNS; overexcitability of the CNS
D.overexcitability of the CNS; depression of the CNS

A

B

368
Q

Which of the following functions in both urinary and reproductive systems in the male?

A.prostate
B.Seminal vesicle
C.Sertoli cells
D.urethra

A

D

369
Q

The function of chemicals within the acrosomal cap is to

A.protect the DNA of the sperm
B.aid the sperm in penetration into a secondary oocyte
C.provide energy for the flagellum
D.provide motility for the sperm

A

B

370
Q

The portion of the penis which surrounds the urethra is the

A.tunica albuginea
B.corpus spongiosum
C.corpus cavernosum
D.prepuce

A

B

371
Q

The fructose in semen is secreted by the

A.epididymis
B.ductus deferens
C.seminal vesicles
D.seminiferous tubules

A

C

372
Q

Sperm move by means of

A.cilia
B.microvilli
C.flagella
D.enzymes

A

C

373
Q

In males, FSH

A.acts indirectly with testosterone to stimulate spermatogenesis
B.stimulates the testes to secrete testosterone
C.has no function
D.causes sperm cells to secrete inhibin

A

A

374
Q

The cells in the testis responsible for producing testosterone are the

A.spermatogenic cells
B.spermatogonia
C.Sertoli cells
D.Leydig cells

A

D

375
Q

The testes are covered by a dense white fibrous capsule called the

A.scrotum
B.tunica vaginalis
C.tunica albuginea
D.visceral peritoneum

A

C

376
Q

Which of the following cells lies next to the basement membrane of the seminiferous tubules?

A.spermatogonia
B.primary spermatocytes
C.secondary spermatocytes
D.spermatids

A

A

377
Q

In the testis, spermatogonia divide by

A.mitosis
B.meiosis
C.reduction division
D.equation division

A

A

378
Q

The cells formed by meiosis II are called

A.spermatogonia
B.primary spermatocytes
C.secondary spermatocytes
D.spermatids

A

D

379
Q

The daily production of sperm in the testes is about

A.30 thousand
B.300 thousand
C.30 million
D.300 million

A

D

380
Q

Which of the hormones produced in the male directly stimulates testosterone secretion?

A.FSH
B.LH
C.inhibin
D.GnRH

A

B

381
Q

In the male, the protein hormone inhibin is produced by the _____ and inhibits secretion of _____.

A.hypothalamus; LH
B.anterior pituitary gland; testosterone
C.Sertoli cells; FSH
D.Leydig cells; GnRH

A

C

382
Q

The longest duct of the male reproductive tract, passing from the scrotum into the pelvic cavity, is the

A.ductus deferens
B.epididymis
C.ejaculatory duct
D.urethra

A

A

383
Q

The ejaculatory duct attaches to the urethra in a region surrounded by the

A.seminal vesicles
B.prostate gland
C.urogenital diaphragm
D.urinary bladder

A

B

384
Q

male is likely to be infertile if his sperm count is below _____ per mL of semen.

A.one thousand
B.ten thousand
C.one million
D.twenty million

A

D

385
Q

The bulb of the penis is located at the base of the

A.corpus cavernosum
B.corpus spongiosum
C.glans penis
D.prepuce

A

B

386
Q

The portion of the ovary that contains the ovarian follicles is the

A.mesovarium
B.germinal epithelium
C.cortex
D.tunica albuginea

A

C

387
Q

Which female reproductive structure is located between the urinary bladder and the rectum?

A.ovary
B.uterus
C.vagina
D.prostate

A

B

388
Q

The perimetrium or serosa is part of the

A.parietal peritoneum
B.visceral peritoneum
C.parietal pleura
D.visceral pericardium

A

B

389
Q

In the ovary, oocytes begin meiosis I

A.during fetal development
B.during early childhood
C.after puberty
D.after ovulation

A

A

390
Q

The open, funnel-shaped portion of a uterine tube is called the

A.fimbria
B.ampulla
C.infundibulum
D.isthmus

A

C

391
Q

Fertilization of the oocyte by a sperm usually occurs in the

A.vagina
B.cervix of the uterus
C.ovary
D.ampulla of the oviduct

A

D

392
Q

The uterus is attached to both sides of the pelvic cavity by the

A.round ligaments
B.broad ligaments
C.oviducts
D.cardinal ligaments

A

B

393
Q

The normal flexure of the uterus, projecting it anteriorly and superiorly over the vagina, is called

A.uterine prolapse
B.dorsiflexion
C.anteflexion
D.retroflexion

A

C

394
Q

A hysterectomy is the

A.downward displacement of the uterus into the vagina
B.most common sterilization procedure used in women
C.surgical procedure sometime used during childbirth to open the vaginal canal
D.surgical removal of the uterus

A

D

395
Q

The stratum basalis of the uterus

A.is shed during menstruation
B.repeatedly gives rise to a new stratum functionalis after each menstruation
C.contracts during childbirth to help expel the fetus
D.is part of the visceral peritoneum and becomes part of the broad ligament

A

B

396
Q

The acidity of the vagina is due to

A.breakdown of glycogen that produces organic acids
B.secretion of small amounts of hydrochloric acid by cells lining the tube
C.reabsorption of bicarbonate ions, reducing their buffering action
D.secretions of bacteria that normally reside in this tube

A

A

397
Q

The small folds that are lateral to the vaginal opening are the

A.hymen
B.clitoris
C.labia minora
D.mons pubis

A

C

398
Q

The milk secreting glands in the breast are called:

A.alveoli
B.lobules
C.lobes
D.lactiferous sinuses

A

A

399
Q

The last tubes through which milk flows before it reaches the outside through the nipple are the:

A.lactiferous ducts
B.lactiferous sinuses
C.mammary ducts
D.secondary tubules

A

A

400
Q

The corpus luteum secretes

A.human chorionic gonadotropin (hCG)
B.progesterone and estrogens
C.hCG and progesterone
D.estrogens and hCG

A

B

401
Q

After ovulation the _____ becomes the _____.

A.secondary oocyte, primary oocyte
B.zona pellucida, corona radiata
C.mature (Graafian) follicle, corpus luteum
D.amount of glucose ingested

A

C

402
Q

Which of the following hormones have the greatest direct control over the changes in the uterus?

A.GnRH
B.FSH and LH
C.estrogens and progesterone
D.inhibin and relaxin

A

C

403
Q

The principal estrogen hormone in the nonpregnant woman is

A.beta-estradiol
B.estrone
C.estriol
D.progesterone

A

A

404
Q

Which hormone has effects on general metabolism to increase protein production and reduce cholesterol production as well as controlling the reproductive cycle in the female?

A.estrogens
B.progesterone
C.FSH
D.LH

A

A

405
Q

__________ increases the flexibility of the pubic symphysis at the end of pregnancy.

A.estrogen
B.progesterone
C.relaxin
D.inhibin

A

C

406
Q

The mature (Graafian) follicle continues to enlarge and increase its estrogen production during the

A.menstrual phase
B.preovulatory phase
C.ovulation phase
D.postovulatory phase

A

B

407
Q

The hormone responsible for stimulating the development of the secondary follicles in the ovary is

A.progesterone
B.FSH
C.LH
D.GnRH

A

B

408
Q

An over-the-counter test is now available for purchase that indicates ovulation. This test measures the levels of

A.estrogens
B.FSH
C.GnRH
D.LH

A

D

409
Q

Low levels of progesterone cause

A.menstruation
B.Inhibition of GnRH
C.a sudden surge of LH
D.inhibition of FSH and LH

A

A

410
Q

Oral contraceptive pills contain estrogens and progestin that

A.cause the developing follicle to degenerate
B.inhibit the secretion of inhibin
C.prevent the development of the endometrium
D.inhibit the release of FSH and LH

A

D

411
Q

The birth control method that is based on knowledge of certain physiological changes that occur during the menstrual cycle is

A.coitus interruptus
B.sympto-thermal
C.the intrauterine device
D.the cervical cap

A

B

412
Q

The epididymis and ductus (vas) deferens develop from the embryonic

A.genital tubercle
B.labioscrotal swelling
C.paramesonephric duct
D.mesonephric duct

A

D

413
Q

Menarche is

A.the same as menopause
B.the permanent cessation of menses
C.the first menses
D.when oogenesis begins

A

C

414
Q

A Pap smear is a test performed to detect

A.cancer of the cervix
B.pregnancy
C.infections of the ovary
D.vaginitis

A

A

415
Q

The American Cancer Society recommends that a woman should have a baseline mammogram taken, to serve as a comparison, between the ages of

A.20 and 24
B.25 and 29
C.30 and 34
D.35 and 39

A

D

416
Q

The intervillous spaces of the placenta

A.are derived from the chorion
B.contain maternal blood
C.are rich in hCG and HCS
D.enlarge under the influence of relaxin

A

B

417
Q

After implantation

A. the morula becomes the blastocyst
B. the trophoblast develops into two layers
C. the embryoblast forms the cytotrophoblast
D. the syncytiotrophoblast is replaced by the blastocoele

A

B

418
Q

By the end of the first month of gestation

A. the fetus has fully formed head with properly located eyes and ears
B. subcutaneous fat is lost and lanugo increases in density
C. ossification is complete, blood formation ends
D. arm and leg buds form and the heart is beating

A

D

419
Q

After implantation, the only tissue of the developing embryo to come in direct contact with maternal tissue is the

A.zona pellucida
B.embryoblast
C.blastocoele
D.trophoblast

A

D

420
Q

Functional changes that sperm undergo in the female reproductive tract which allow them to fertilize a secondary oocyte are termed

A.syngamy
B.fertilization
C.capacitation
D.implantation

A

C

421
Q

Implantation is the process where the

A. egg is fertilized by the sperm
B. sperm is deposited in the vagina
C. blastocyst attaches to and enters the endometrium
D. cervix becomes plugged with mucus to prevent the entry of more sperm

A

C

422
Q

Implantation occurs _____ after fertilization.

A.immediately
B.a few hours
C.a day
D.about 6 days

A

D

423
Q

The developing embryo is surrounded by and bathed in:

A.amniotic fluid
B.chorionic fluid
C.fluid in the yolk sac
D.plasma from the mother

A

A

424
Q

The embryonic portion of the placenta develops from the

A.amnion
B.yolk sac
C.chorion
D.allantois

A

C

425
Q

In the umbilical cord, there are
A.
two arteries that carry oxygenated blood and one vein that carries deoxygenated blood

B. one artery that carries oxygenated blood and one vein that carries deoxygenated blood
C. one artery that carries deoxygenated blood and two veins that carries deoxygenated blood
D. two arteries that carry deoxygenated blood and one vein that carries oxygenated blood

A

D

426
Q

The testes have descended into the scrotal sac of a male fetus that is

A.in the second month of development
B.in the third month of development
C.in the fifth month of development
D.full-term

A

D

427
Q

What is an agent that causes developmental defects in the embryo called?

A.antibody
B.gene splice
C.antigen
D.teratogen

A

D

428
Q

Amniocentesis can produce results that indicate

A.successful implantation
B.the beginning of a normal pregnancy
C.the presence of certain genetic disorders such as Down syndrome
D.the onset of labor

A

C

429
Q

Early pregnancy tests depend on the detection of _____ in the urine.

A.estrogen
B.human chorionic gonadotropin
C.chorionic progesterone
D.follicle stimulating hormone

A

B

430
Q

Chorionic villi sampling (CVS), although riskier, has an advantage over amniocentesis because CVS

A.involves removal of fluid only
B.never has any negative side effects
C.yields test results in a few days
D.can be performed during the second week of pregnancy

A

C

431
Q

At the end of a full-term of pregnancy, the top of the uterus reaches

A.the top of the pelvic rim
B.the level of the umbilicus (navel)
C.the lower surface of the stomach
D.nearly to the xyphoid process of the sternum

A

D

432
Q

The placental stage of labor ends with

A.delivery of the newborn
B.rupture of the amniotic sac
C.expelling of the after birth
D.dilation of the cervix

A

C

433
Q

If pregnancy continues for two weeks beyond the due date, there is a chance of brain damage to the fetus because of

A.breakdown of fetal red blood cells
B.an aging placenta
C.overstretching of the uterus
D.disintegration of the umbilical cord

A

B

434
Q

Which of the following is NOT a change that occurs after birth, as a fetus becomes a newborn baby?

A.the lungs fill with air for the first time
B.the umbilical arteries fill with connective tissue
C.the ductus arteriosus provides a connection to the inferior vena cava
D.foramen ovale closes and becomes the fossa ovalis

A

C

435
Q

In the process of lactation

A.the posterior pituitary releases prolactin that initiates milk ejection
B.feeding inhibits the release of oxytocin, thus ensuring the continuation of lactation
C.the uterine smooth muscle returns to its normal size more rapidly in nursing than non-nursing mothers
D.the estrogen and progesterone in colostrum stimulate growth of the newborn nervous system

A

C

436
Q

A hormone called _____, released from the anterior pituitary gland stimulates the production of milk by the mammary glands.

A.relaxin
B.oxytocin
C.prolactin
D.luteinizing hormone

A

C

437
Q

If a man with hemophilia marries a woman who does not carry the hemophilia gene, which of the following concerning their children is probable?

A.All of the sons will be carriers
B.All of the sons will have hemophilia
C.All of the daughters will be carriers
D.One half of the sons will have hemophilia and one half will be carriers

A

C

438
Q

A mother with blood type B and a father with blood type A have four children. One child is type AB, one is A, one is B, and one is type O. Which of the following represents the genotypes of the parents?

A.IA i x IB i
B.IA IA x IB i
C.IA i x IB IB
D.IA IA x IB i

A

A

439
Q

The phenotype of an individual refers to the

A.genetic makeup of the chromosomes
B.type of mutations that are present
C.the type of dominant and recessive genes
D.physical or outward expression of a gene

A

D

440
Q

If a couple are both heterozygous for the gene that causes phenylketonuria, the probability that their first child will have PKU is

A.25 percent
B.50 percent
C.75 percent
D.100 percent

A

A

441
Q

Sickle-cell disease is an example of

A.a dominant-recessive trait
B.sex-linked inheritance
C.incomplete dominance
D.multiple allele inheritance

A

C

442
Q

How many alleles are present in humans that produce the phenotypes of the four blood types of the ABO blood groups?

A.one
B.two
C.three
D.four

A

C

443
Q

An embryo develops into a normal baby girl because it

A.is exposed to very high levels of estrogen during development
B.received two X chromosomes from its mother
C.has two copies of the SRY gene
D.lacks the SRY gene

A

D

444
Q

The gene for red-green colorblindness is represented by the symbol ‘c’. The normal allele is represented by ‘C’. An individual with the genotype XC Xc would be a

A.color-blind female
B.normal carrier female
C.normal male
D.color-blind male

A

B

445
Q

Fertilization in a laboratory dish and transfer of the developing embryo into the uterus is called

A.in vitro fertilization
B.embryo transfer
C.gamete intrafallopian transfer (GIFT)
D.ectopic pregnancy

A

A

446
Q

1) Which is not a major function of the kidney?

a) regulation of blood ionic composition
b) regulation of blood cell size
c) regulation of blood volume
d) regulation of blood pressure
e) regulation of blood pH

A

Answer: b

447
Q

This is the formation of a new glucose molecule.

a) glycolysis
b) gluconeogenesis
c) glucosamine
d) glucose
e) calcitriol

A

Answer: b

448
Q

Which of the following is a waste product normally excreted by the kidneys?

a) urea
b) glucose
c) insulin
d) cholesterol
e) carbon dioxide

A

Answer: a

449
Q

This is smooth dense irregular connective tissue that is continuous with the outer coat of the ureter.

a) adipose capsule
b) renal capsule
c) renal hilus
d) renal cortex
e) renal medulla

A

Answer: b

450
Q

The portion of the kidney that extends between the renal pyramids is called the

a) renal columns
b) renal medulla
c) renal pelvis
d) calyces
e) renal papilla

A

Answer: a

451
Q

Which is the correct order of blood flow through the kidneys?

a) renal artery > segmental artery > interlobular artery > peritubular capillaries > afferent arterioles
b) interlobar arteries > arcuate arteries > glomerular capillaries > arcuate veins
c) arcuate veins > arcuate arteries > glomerular capillaries > renal vein
d) renal vein > segmental arteries > interlobar arteries > efferent arterioles
e) interlobar veins > afferent arterioles > efferent arterioles > glomerular capillaries

A

Answer: b

452
Q

Which is the correct order of filtrate flow?

a) glomerular capsule, proximal convoluted tubule (PCT), loop of Henle, distal convoluted tubule (DCT), collecting duct
b) loop of Henle, glomerular capsule, PCT, DCT, collecting duct
c) ascending limb of loop, PCT, DCT, collecting duct
d) collecting duct, DCT, PCT, collecting duct, glomerular capsule
e) PCT, glomerular capsule, DCT, collecting duct, loop of Henle

A

Answer: a

453
Q

Which structure of the nephron reabsorbs the most substances?

a) glomerular capsule
b) loop of Henle
c) ascending limb
d) collecting duct
e) proximal convoluted tubule

A

Answer: e

454
Q

This is the structure of the nephron that filters blood.

a) glomerular capsule
b) loop of Henle
c) ascending limb
d) collecting duct
e) renal corpuscle

A

Answer: a

455
Q

This term means the return of substances into the blood stream from the filtrate.

a) reabsorption
b) filtration
c) secretion
d) excretion
e) none of these choices

A

Answer: a

456
Q

This is a nephron process that results in a substance in blood entering the already formed filtrate.

a) reabsorption
b) filtration
c) secretion
d) excretion
e) none of these choices

A

Answer: c

457
Q

his layer of filtration membrane is composed of collagen fibers and proteoglycans in a glycoprotein matrix.

a) glomerular endothelial cells
b) basal lamina
c) pedicels
d) filtration slits
e) slit membrane

A

Answer: b

458
Q

This occurs when stretching triggers contraction of smooth muscle walls in afferent arterioles.

a) glomerular filtration rate
b) tubulomerular feedback
c) myogenic mechanism
d) renal autoregulation
e) capsular hydrostatic pressure

A

Answer: c

459
Q

This occurs when a substance passes from the fluid in the tubular lumen through the apical membrane, across the cytosol, and then into the interstitial fluid.

a) paracellular reabsoprtion
b) transcellular reabsoprtion
c) apical reasborption
d) basolateral reabsorption
e) active transport

A

Answer: b

460
Q

The proximal convoluted tubules reabsorb which percentage of filtered water?

a) 25%
b) 50%
c) 65%
d) 80%
e) 99%

A

Answer: c

461
Q

Which of the following is NOT a way angiotensin II affects the kidneys?

a) It increases GFR b) It can decrease GFR c) It enhances reabsorption of certain ions d) It stimulates the release of aldosterone e) None of these choices

A

Answer: a

462
Q

Urea recycling can cause a buildup of urea in the

a) renal capsule
b) loop of Henle
c) ascending tubule
d) renal medulla
e) renal pelvis

A

Answer: d

463
Q

Increased secretion of hydrogen ions would result in a ______________ of blood ____________?

a) increase, pressure
b) decrease, volume
c) increase, sodium levels
d) decrease, pH e) increase, urea

A

Answer: d

464
Q

Increased secretion of aldosterone would result in a ______________ of blood ____________?

a) increase, potassium
b) decrease, volume
c) increase, calcium levels
d) decrease, pH
e) increase, sodium

A

Answer: e

465
Q

An analysis of the physical, chemical, and microscopic properties of urine is called

a) urinalysis
b) filtration study
c) concentration study
d) diuretic
e) osmolarity

A

Answer: a

466
Q

Water accounts for which percentage of the total volume of urine?

a) 25%
b) 50%
c) 75%
d) 80%
e) 95%

A

Answer: e

467
Q

This is a test to measure kidney function.

a) Plasma creatinine
b) Renal study
c) Kidney assay
d) Dialysis
e) Hilus study

A

Answer: a

468
Q

This transports urine from the kidney to the bladder.

a) Urethra
b) Ureter
c) Descending loop of Henle
d) Renal hilus
e) None of these choices

A

Answer: b

469
Q

This layer of the ureter is composed of connective tissue, collagen and elastic fibers.

a) Mucosa
b) Transitional epithelium
c) Lamina propria
d) Adventitia
e) Lamina elastica

A

Answer: c

470
Q

This lies in the anterior corner of the trigone of the bladder.

a) Urethral sphincter
b) Adventitia bundle
c) Ureter
d) Internal urethral orifice
e) Muscularis bundle

A

Answer: d

471
Q

An increase in permeability of the filtration membrane due to disease, injury, or irritation of kidney cells by substances such as bacterial toxins, ether, or heavy metals indicates which condition?

a) albuminuria
b) lucosuria
c) robilinogenuria
d) ketonuria
e) bilirubinuria

A

Answer: a

472
Q

Anorexia, starvation, or a diet too low in carbohydrates indicates which condition?

a) albuminuria
b) glucosuria
c) urobilinogenuria
d) ketonuria
e) bilirubinuria

A

Answer: d

473
Q

Stress, causing excessive amounts of epinephrine secretion which stimulates glycogen breakdown, indicates which condition? This condition can also indicate diabetes mellitus.

a) albuminuria
b) glucosuria
c) urobilinogenuria
d) hematuria
e) bilirubinuria

A

Answer: b

474
Q

Excessive urine concentration of a normal breakdown product of hemoglobin, caused by pernicious anemia, infectious hepatitis, jaundice or cirrhosis, indicates which condition?

a) albuminuria
b) glucosuria
c) urobilinogenuria
d) hematuria
e) bilirubinuria

A

Answer: c

475
Q

This substance gives bile its major pigmentation:

a) ketone bodies
b) erythrocytes
c) casts
d) bilirubin
e) glucose

A

Answer: d

476
Q

These are tiny masses of material, hardened in the lumen of the urinary tubule and are flushed out when filtrate builds up behind them:

a) ketone bodies
b) erythrocytes
c) casts
d) microbes
e) urobilinogen

A

Answer: c

477
Q

Candida albicans and E. coli are which type of abnormal constituent of urine:

a) ketone bodies
b) erythrocytes
c) casts
d) microbes
e) urobilinogen

A

Answer: d

478
Q

Which is the normal pH range of urine in humans?

a) 8.1 –10.6
b) 4.6 –8.0
c) 1.0 –3.0
d) 3.1 –4.0
e) 10.0 –12.0

A

Answer: b

479
Q

What is the normal volume of urine produced in humans?

a) 1L / hr
b) 2L / day
c) 2L / hr
d) 3L / week
e) 10L / 24 hours

A

Answer: b

480
Q

What is the normal specific gravity range of urine in humans?

a) 2.350 – 3.700
b) 0.002 – 1.000
c) 4.6 – 8.0
d) 1.001 – 1.035
e) 1.04 – 2.60

A

Answer: d

481
Q

This hormone is released when the blood volume increases.

a) Parathyroid Hormone
b) Renin
c) ADH
d) Atrial Natriuretic Peptide
e) Aldosterone

A

Answer: d

482
Q

Consumption of salty food will cause an increase in this hormone.

a) Aldosterone
b) Renin
c) ANH
d) Angiotensin-II
e) ADH

A

Answer: e

483
Q

Absence of angiotensin converting enzyme will lead to

a) decreased blood pressure
b) increased blood pressure
c) will not have any effect on blood pressure
d) All of these choices
e) None of these choice

A

Answer: a

484
Q

How much of the total volume of body fluid is intracellular fluid?

a) 10%
b) 50%
c) 1/3
d) 2/3
e) 99%

A

d

485
Q

80% of the extracellular fluid is

a) Plasma
b) Cytosol
c) Interstitial fluid
d) Lymph
e) Bile

A

c

486
Q

This is the largest single component of the human body.

a) Skin
b) Water
c) Blood
d) Organs
e) Electrolytes

A

b

487
Q

This is produced when electrons are accepted by oxygen during cellular respiration.

a) Anions
b) Cations
c) Metabolic water
d) Lipids
e) Carbohydrates

A

c

488
Q

This occurs when water loss is greater than water gain.

a) Dehydration
b) Evaporation
c) Precipitation
d) Insensible loss
e) None of these choices

A

a

489
Q

The response of the body to decreasing blood pressure will NOT cause which of the following?

a) Dehydration
b) Formation of angiotensin II
c) Stimulate the kidneys to secrete rennin
d) Formation of ADH
e) Increased vasoconstriction

A

e

490
Q

This is the main factor that determines body fluid volume.

a) Thirst center
b) Fluid balance
c) Urinary salt loss
d) Compartmentalizing
e) None of these choices

A

c

491
Q

Which of the following is used to promote Na+ reabsorption by the kidneys?

a) Antidiuretic hormone
b) ANP
c) Aldosterone
d) Parathyroid hormone
e) All of these choices

A

c

492
Q

Which of the following is used to promote water reabsorption by the kidneys?

a) Antidiuretic hormone
b) ANP
c) Aldosterone
d) Parathyroid hormone
e) All of these choices

A

a

493
Q

Natriuresis

a) Is decreased Na+ levels in urine
b) Is decreased Cl- levels in urine
c) Is increased K+ levels in urine
d) Is increased PO- levels in urine
e) None of these choices

A

e

494
Q

A decline in angiotensin II levels does NOT result in

a) Increased GFR
b) Reduced Na+ and Cl- reabsorption by the kidneys
c) Reduced water reabsorption by the kidneys
d) Increased Calcium reabsorption
e) Increased urine output

A

d

495
Q

The major hormone that regulates water loss is

a) ANP
b) Angiotensin II
c) Renin
d) ADH
e) Angiotensin

A

d

496
Q

Water intoxication results from

a) Dilute body fluids
b) Decrease in the osmolarity of interstitial fluids
c) Osmosis of water from ICF to ECF
d) Dilute body fluids and a decrease in the osmolarity of interstitial fluids
e) Decrease in water intake

A

d

497
Q

Which of the following is a function of an electrolyte in the body?

a) Controlling osmosis between compartments
b) Maintaining acid-base balance
c) Carry electrical currents
d) Serve as cofactors
e) All of these choices

A

e

498
Q

In extracellular fluid the most abundant cation is

a) Na+
b) Cl-
c) K+
d) HPO42-
e) HCO3-

A

a

499
Q

In extracellular fluid the most abundant anion is:

a) Na+
b) Cl-
c) K+
d) HPO42-
e) HCO3-

A

b

500
Q

In intracellular fluid the most abundant cation is:

a) Na+
b) Cl-
c) K+
d) HPO42-
e) HCO3-

A

c

501
Q

In intracellular fluid the most abundant anion is

a) Na+
b) Cl-
c) K+
d) HPO42-
e) HCO3-

A

d

502
Q

The Na+ level in blood is controlled by

a) Aldosterone
b) Insulin
c) ATP production
d) Krebs cycle
e) Glucagon

A

a

503
Q

This occurs between RBC and blood plasma as the blood level of carbon dioxide increases or decreases.

a) Chloride shift
b) Potassium shift
c) Sodium shift
d) Bicarbonate shift
e) Protein shift

A

a

504
Q

This is the most abundant mineral in the body.

a) Na+
b) Calcium
c) Magnesium
d) Phosphate
e) Proteins

A

b

505
Q

PTH, calcitriol and calcitonin are

a) The main regulators of magnesium in the blood
b) The main regulators of phosphate in the blood
c) The main regulators of calcium in the blood
d) The main regulators of NaCl in the blood
e) None of these choices

A

c

506
Q

Most of the phosphate in a body is present as

a) Lipids
b) Plasma membranes
c) DNA
d) Calcium phosphate salt
e) Carbohydrates

A

d

507
Q

Buffer systems, exhaling carbon dioxide and excretion by the kidneys are all

a) Ways to balance interstitial fluid
b) Means of balancing blood volume
c) Ways of controlling H+ levels in the body
d) Ways to make ions e) Ways to increase blood volume

A

c

508
Q

Metabolic reactions can produce

a) H+
b) HCO3-
c) Nonvolatile acids
d) Volatile bases
e) Ca+

A

c

509
Q

This is a condition where blood pH is below 7.35

a) Isodosis
b) Acidosis
c) Alkalosis
d) Alkalemia
e) None of these choices

A

b

510
Q

In partial compensation

a) pH is brought into the normal range
b) systemic arterial blood is still lower than 7.35
c) systemic arterial blood is higher than 9.5
d) pH is greater than 5.5
e) pH is lower than 2.5

A

b

511
Q

Inadequate exhalation of carbon dioxide can cause

a) Blood pH to drop b) Alkalosis
c) Respiratory compensation
d) Unequal distribution of water
e) Metabolic alkalosis

A

a

512
Q

This imbalance results when systemic arterial blood HCO3- levels drop significantly (below 22 mEq/liter)

a) Metabolic alkalosis
b) Metabolic acidosis
c) Respiratory acidosis
d) Respiratory alkalosis e) None of these choices

A

b

513
Q

This imbalance results when systemic arterial blood CO2 levels raise to abnormal values.

a) Metabolic alkalosis
b) Metabolic acidosis
c) Respiratory acidosis
d) Respiratory alkalosis e) None of these choices

A

c

514
Q

This is the most common cause of metabolic alkalosis.

a) Hemorrhage
b) Vomiting
c) Pneumothroax
d) Diabetes
e) Cancer

A

b

515
Q

The rate of fluid intake and outflow is how much higher in an infant than in an adult?

a) 2 times higher
b) 5 times higher
c) 7 times higher
d) 10 times higher
e) They are equal

A

c

516
Q

The breathing rate of an infant

a) Is twice as fast as an adult
b) Causes greater water loss from the lungs
c) Removes less carbon dioxide than in an adult
d) Makes the infant blood more acidic e) Is normal to an adult

A

b

517
Q

This structure helps regulate the temperature of the testes

a) Dartos muscle
b) Tunica vaginalis
c) Tunica albuginea
d) Seminiferous tubules
e) Both Dartos muscle and Seminiferous tubules

A

a

518
Q

This structure is the site of sperm production.

a) Vas deferens
b) Seminiferous tubules
c) Albuginea
d) Epididymis
e) Raphe

A

b

519
Q

How many seminiferous tubules are found in each lobule?

a) 1-3
b) 50-100
c) 200-300
d) 500 or more
e) Millions

A

a

520
Q

These cells may eventually become spermatozoa

a) Sertoli cells
b) Sustentacular cells
c) Spermatogonia
d) Chief cells
e) Speciation cells

A

c

521
Q

These cells secrete testosterone.

a) Sertoli cells
b) Spermatogenic cells
c) Leydig cells
d) Oogonia
e) Chief cells

A

c

522
Q

This hormone stimulates Leydig cells to secrete testosterone.

a) GnRH
b) LH
c) Inhibin
d) DHT
e) None of these choices

A

b

523
Q

The straight tubules in the testis lead into the

a) Efferent ducts
b) Afferent ducts
c) Rete testis
d) Ductus epididymis
e) Epididymis

A

c

524
Q

The function of the epididymis is

a) Sperm maturation
b) Produce sperm
c) Spermatid storage
d) Provide nutrition to sperm
e) Absorption of calcium

A

a

525
Q

This is formed by the union of the duct from the seminal vesicle and the ampulla of the vas deferens.

a) Urethra
b) Spermatic cord
c) Inguinal canal
d) Ejaculatory duct
e) Prostate

A

d

526
Q

This lies posterior to the bladder and anterior to the rectum and secretes an alkaline, fructose filled fluid.

a) Prostate
b) Cowper’s glands
c) Seminal vesicles
d) Spongy urethra
e) Prostatic urethra

A

c

527
Q

These are located inferior to the prostate on either side of the membranous urethra within the deep muscles of the perineum.

a) Cowper’s glands
b) Seminal vesicles
c) Ejaculatory ducts
d) Urethral ducts
e) Prostate

A

a

528
Q

This is composed of three cylindrical masses of erectile tissue each surrounded by a fibrous tissue.

a) Testes
b) Prostate
c) Bladder
d) Penis
e) Urethra

A

d

529
Q

This ligament arises from the pubic symphysis in males.

a) Fundiform ligament
b) Broad ligament
c) Suspensory ligament
d) Ejaculatory ligament
e) Perineum ligament

A

c

530
Q

What is produced by the ovaries?

a) Primary oocytes, insulin and estrogen
b) Secondary oocytes, progesterone and cortisol
c) Tertiary oocytes, insulin and estrogen
d) Secondary oocytes, estrogen and progesterone
e) Primary oocytes, estrogen and testosterone

A

d

531
Q

This attaches the ovaries and the uterus to the pelvic wall.

a) Broad ligament
b) Mesovarium
c) Ovarian ligament
d) Suspensory ligament
e) Hilum

A

d

532
Q

This is the site of fertilization.

a) Ureters
b) Urethra
c) Uterine tubes
d) Ovaries
e) Vagina

A

c

533
Q

This is the portion of the uterus that opens into the vagina.

a) Urethra
b) Cervix
c) Uterine tubes
d) Inguinal canal
e) Ovaries

A

b

534
Q

Anterior to the vagina and urethral openings is the

a) Labia majora
b) Labia minor
c) Mons pubis
d) Cervical sphincter
e) Labial frenulum

A

c

535
Q

Skene’s glands secrete

a) Estrogen
b) Progesterone
c) Testosterone
d) Androgens
e) Mucus

A

e

536
Q

This hormone promotes the final step of spermatogenesis.

a) Relaxin
b) Testosterone
c) Inhibin
d) Estrogen
e) Aldosterone

A

b

537
Q

This hormone triggers ovulation.

a) GnRH
b) LH
c) FSH
d) Estrogen
e) Progesterone

A

b

538
Q

This is secreted by the corpus luteum after ovulation.

a) Progesterone
b) Relaxin
c) LH
d) FSH
e) HGH

A

a

539
Q

This is the uterine phase when the thickness of the endometrium doubles.

a) Menstrual phase
b) Preovulatory phase
c) Proliferative phase
d) Follicular phase
e) Postovulatory phase

A

c

540
Q

This is the ovarian phase between the end of menstruation and beginning of ovulation.

a) Menstrual phase
b) Preovulatory phase
c) Proliferative phase
d) Follicular phase
e) Postovulatory phase

A

b

541
Q

Male reproductive system arises from

a) Mullerian ducts
b) Wolffian ducts

A

b

542
Q

Female reproductive system arises from

a) Mullerian ducts
b) Wolffian ducts

A

a

543
Q

During fetal development these cells give rise to primary oocytes.

a) Spermatogonia
b) Secondary oocytes
c) Oogonia
d) Granulosa cells
e) Luteal cells

A

c

544
Q

The major hormone secreted from granulosa cells is

a) Progesterone
b) Estrogen
c) Testosterone
d) Aldosterone
e) Relaxin

A

b

545
Q

Zygote is

a) the same as an ovum
b) another name for secondary oocyte
c) a diploid fertilized ovum
d) the same as polar body
e) the Graffian follicle

A

c

546
Q

This hormone inhibits the release of FSH from the pituitary gland.

a) Inhibin
b) Relaxin
c) GnRH
d) hCG
e) LH

A

a

547
Q

In male embryos, this hormone is responsible for the development of the urethra, prostate, and external genitals.

a) LH
b) FSH
c) Progesterone
d) Esterogen
e) Dihydrotestosterone

A

e

548
Q

Fertilization normally occurs within which structure?

a) Ovary
b) Fallopian tube
c) Ovarian ligament
d) Body of uterus
e) Vagina

A

b

549
Q

This is a series of functional changes that sperm go through when they are in the female reproductive tract.

a) Acrosomal reaction
b) Maturation
c) Fertilization
d) Capacitation
e) Polyspermy

A

d

550
Q

The fusion of the male pronucleus and the female pronucleus results in which developmental stage?

a) Female pronucleus
b) Male pronucleus
c) Zygote
d) Blastomeres
e) Morula

A

c

551
Q

This is the part of the blastocyst that promotes implantation and produces hCG.

a) Blastocyte
b) Blastosphere
c) Trophoblast
d) Blastocyst cavity
e) Uterine cavity

A

Answer: c

552
Q

This is the portion of the endometrium that lies between the embryo and the stratum basalis.

a) Decidua basalis
b) Decidua capsularis
c) Decidua parietalis
d) Lamina propria
e) Adventitia

A

a

553
Q

This develops from the epiblast and carries a protective fluid.

a) Cytotrophoblast
b) Yolk sac
c) Exocoelomic membrane
d) Amnion
e) Lacunae

A

d

554
Q

This will become the primary structure for exchange of material between the mother and the fetus.

a) Chorionic villi of the placenta
b) Amnion
c) Amnionic fluid
d) Embryonic disc
e) Endoderm

A

Answer: a

555
Q

Each somite may differentiate into a

a) Sertoli cell
b) Dermatome
c) Ovary
d) Myogenic cells
e) Ductus deferens

A

Answer: b

556
Q

This is the connection between the placenta and the embryo.

a) Amnion
b) Chorion
c) Umbilical cord
d) Placenta
e) Capillary beds

A

Answer: c

557
Q

How many pairs of pharyngeal arches are there?

a) 2
b) 3
c) 4
d) 5
e) 6

A

Answer: d

558
Q

This is any agent or influence that causes developmental defects in an embryo.

a) Carcinogen
b) Toxin
c) Nicotine
d) Radiation
e) None of these choices

A

Answer: e

559
Q

This exam is performed between 14-16 weeks gestation and is used to detect genetic abnormalities.

a) Sonogram
b) Amniocentesis
c) CVS
d) AFP test
e) CBC

A

Answer: b

560
Q

CVS is taking cells from where?

a) Amnion
b) Chorion
c) Placenta
d) Umbilical cord
e) Uterus

A

Answer: b

561
Q

This hormone is secreted by nonpregnant women from neurosecretory cells in the hypothalamus.

a) GnRH
b) hCG
c) CRH
d) AFP
e) ATP

A

Answer: c

562
Q

During pregnancy stroke volume can increase by

a) 10%
b) 20%
c) 30%
d) 40%
e) 50%

A

Answer: c

563
Q

Labor cannot take place until all of this hormone’s effects are diminished.

a) Estrogen
b) Progesterone
c) Testosterone
d) Relaxin
e) Inhibin

A

Answer: b

564
Q

This is the time from the onset of labor to the complete dilation of the cervix.

a) Stage of dilation
b) Stage of expulsion
c) Placental stage
d) Gestation
e) Effacement

A

Answer: a

565
Q

Involution is

a) When the placenta is expelled
b) When the umbilical cord is cut
c) When the uterus decreases in size
d) When the cervix dilates
e) None of these choices

A

Answer: c

566
Q

infants this connects the umbilical vein to the inferior vena cava.

a) Ductus venosus
b) Ductus arteriosus
c) Anteriosum
d) Patent ductus arteriosus
e) Superior vena cava

A

Answer: a

567
Q

This is a principle hormone that releases milk into the mammary ducts.

a) Prolactin
b) PIH
c) PRH
d) Oxytocin
e) GnRH

A

Answer: d

568
Q

This is a permanent change in an allele.

a) Mutation
b) Phenotype
c) Genotype
d) Dominant
e) Recessive

A

Answer: a

569
Q

When phenotype can be drastically different depending on parental origin it is called:

a) Mutation
b) Translocation
c) Genomic imprinting
d) Incomplete dominance
e) Codominance

A

Answer: c

570
Q

An example of incomplete dominance is

a) ABO blood groups
b) Sickle-cell disease
c) Angelman Syndrome
d) Prader-Willi Syndrome
e) PKU

A

Answer: b

571
Q

If one parent has type A blood and one parent has type B blood, what blood type is possible for their child?

a) AB
b) A
c) B
d) O
e) All of these choices

A

Answer: e

572
Q

If a child has B blood, and the mother has B blood, what is the possible genotype of the father?

a) B
b) O
c) AB
d) B or O
e) B, O or AB

A

Answer: e

573
Q

Chromosome #15 is considered

a) A sex chromosome
b) An autosome
c) The SRY chromosome
d) A linked gene
e) A transposon

A

Answer: b

574
Q

A Barr body

a) Is an inactivated X chromosome
b) Cannot be stained
c) Are transcribed and translated
d) Is seen in males
e) Is only found in humans

A

Answer: a

575
Q

Which condition listed is a malpresentation in which the fetal buttocks or lower limbs present into the maternal pelvis?

a) Emesis gravidarum
b) Deformation
c) Turner’s syndrome
d) breech presentation
e) Klinefelter’s syndrome

A

Answer: d

576
Q

Which condition listed is a developmental abnormality due to mechanical forces that mold a part of the fetus over a prolonged period of time?

a) Emesis gravidarum
b) Deformation
c) Turner’s syndrome
d) breech presentation
e) Klinefelter’s syndrome

A

Answer: b

577
Q

Clubfeet is an example of which condition listed?

a) Emesis gravidarum
b) Deformation
c) Turner’s syndrome
d) breech presentation
e) Klinefelter’s syndrome

A

Answer: b

578
Q

Which condition listed is also called morning sickness?

a) Emesis gravidarum
b) Deformation
c) Turner’s syndrome
d) breech presentation
e) Klinefelter’s syndrome

A

Answer: a

579
Q

Which condition listed is a sex chromosome aneuploidy, usually due to trisomy XXY?

a) Emesis gravidarum
b) Deformation
c) Turner’s syndrome
d) breech presentation
e) Klinefelter’s syndrome

A

Answer: e

580
Q

Which condition listed gives rise to individuals that are: somewhat mentally disadvantaged, sterile males with undeveloped testes, scant body hair, and enlarged breasts?

a) Emesis gravidarum
b) Deformation
c) Turner’s syndrome
d) breech presentation
e) Klinefelter’s syndrome

A

Answer: e

581
Q

Which condition listed is a sex chromosome aneuploidy, caused by the presence of a single X chromosome designated XO?

a) Emesis gravidarum
b) Deformation
c) Turner’s syndrome
d) breech presentation
e) Klinefelter’s syndrome

A

Answer: c

582
Q

Which condition listed gives rise to sterile females with virtually no ovaries and limited development of secondary sex characteristics?

a) Emesis gravidarum
b) Deformation
c) Turner’s syndrome
d) breech presentation
e) Klinefelter’s syndrome

A

Answer: c

583
Q

Which condition listed is an infectious disease of childbirth resulting from an infection originating in the birth canal and affecting the mother’s endometrium?

a) Emesis gravidarum
b) Puerperal fever
c) Turner’s syndrome
d) Fetal alcohol syndrome
e) Klinefelter’s syndrome

A

Answer: b

584
Q

Which condition listed is a sex chromosome aneuploidy characterized by at least 3 X chromosomes (XXX)?

a) Emesis gravidarum
b) Metafemale syndrome
c) Turner’s syndrome
d) lethal gene
e) Klinefelter’s syndrome

A

Answer: b

585
Q

Which condition listed is one of the most common causes of mental retardation and the most common preventable cause of birth defects in the United States?

a) Emesis gravidarum
b) Metafemale syndrome
c) Turner’s syndrome
d) Fetal alcohol syndrome
e) Klinefelter’s syndrome

A

Answer: d

586
Q

Which of the terms below describes the development of an organism from an undifferentiated cell?

a) conceptus
b) primordium
c) epigenesis
d) karyotype
e) fertilization age

A

Answer: c

587
Q

Which of the terms below includes all structures that develop from a zygote: the embryo, the embryonic placenta and its associated membranes?

a) conceptus
b) primordium
c) epigenesis
d) gestational age
e) karyotype

A

Answer: a

588
Q

Which of the terms below describes the beginning or first discernable indication of the development of an organ or structure?

a) conceptus
b) primordium
c) epigenesis
d) karyotype
e) fertilization age

A

Answer: b

589
Q

Which of the terms below describes the chromosomal characteristic of an individual presented as a systematic arrangement of pairs of metaphase chromosomes arranged by size?

a) conceptus
b) primordium
c) epigenesis
d) karyotype
e) fertilization age

A

Answer: d

590
Q

What is the term used to describe the age of an embryo or fetus calculated from the presumed first day of the last normal menstrual period?

a) conceptus
b) primordium
c) epigenesis
d) gestational age
e) fertilization age

A

Answer: d

591
Q

In a heterozygous individual for a certain trait, the dominant allele gives polydactyly. What is the masked, recessive trait in this individual?

a) normal vision
b) brachydactyly
c) normal digits
d) syndactylism
e) straight thumb

A

Answer: c

592
Q

In a heterozygous individual for a certain trait, the dominant allele gives syndactylism. What is the masked, recessive trait in this individual?

a) normal vision
b) brachydactyly
c) normal digits
d) polydactyly
e) straight thumb

A

Answer: c

593
Q

In a heterozygous individual for a certain trait, the dominant allele gives Huntington’s disease. What is the masked, recessive trait in this individual?

a) normal vision
b) normal digits
c) normal nervous system
d) polydactyly e) straight thumb

A

Answer: c

594
Q

In a heterozygous individual for a certain trait, the dominant allele gives normal skin pigmentation. What is the masked, recessive trait in this individual?

a) normal vision
b) albinism
c) normal nervous system
d) polydactyly
e) cystic fibrosis

A

Answer: b

595
Q

Which of the following is NOT a function of the lymphatic and immune system?

a) Draining excess interstitial fluid
b) Maintaining water homeostasis in the body
c) Transporting dietary lipids
d) Carrying out immune responses

A

Answer: b

596
Q

What is the major difference between lymph and interstitial fluid?

a) Composition of electrolytes
b) White blood cells are present in lymph
c) Location
d) Types of proteins present
e) Red blood cells are present in interstitial fluid

A

Answer: c

597
Q

Lack of resistance is also known as:

a) Pathogenic
b) Innate
c) Specific
d) Susceptibility
e) Lymphatic

A

Answer: d

598
Q

What causes lymph from the small intestines to appear white?

a) Proteins
b) WBC
c) RBC
d) Lipids
e) Carbohydrates

A

Answer: d

599
Q

Which of the following is not considered an organ of the immune system?

a) Spleen
b) Lymph node
c) Red bone marrow
d) Thymus
e) Pancreas

A

Answer: e

600
Q

The left subclavian vein receives lymph from

a) Left axillary vein
b) Lumbar trunk
c) Jugular trunk
d) Thoracic duct
e) Right lymphatic duct

A

Answer: d

601
Q

The lymph from the right foot empties into the

a) Left axillary vein
b) Lumbar trunk
c) Jugular trunk
d) Thoracic duct
e) Right lymphatic duct

A

Answer: d

602
Q

The skeletal muscle and respiratory pumps are used in

a) Lymphatic system
b) Cardiovascular system
c) Immune system
d) Lymphatic and Immune systems only
e) Lymphatic, Immune and Cardiovascular systems

A

Answer: e

603
Q

Which organ produces a hormone that promotes maturation of T cells?

a) Spleen
b) Lymph node
c) Red bone marrow
d) Thymus
e) Pancreas

A

Answer: d

604
Q

In which part of the thymus are T cells thought to die?

a) Capsule
b) Trabeculae
c) Epithelial cells
d) Hassall’s corpuscles
e) T cells do not die in the thymus

A

Answer: d

605
Q

Which portion of the lymph node does not contain any lymphatic nodules.

a) Inner cortex
b) Outer cortex

A

Answer: a

606
Q

Which of the following is a function of the spleen?

a) Removes worn out blood cells
b) Circulates lymph
c) Cleanses interstitial fluid
d) Cleanses lymph
e) Traps microbes with mucus

A

Answer: a

607
Q

Which of these does NOT provide a physical or chemical barrier?

a) Macrophages
b) Saliva
c) Urine
d) Mucus
e) Stratified squamous epithelium

A

Answer: a

608
Q

Which of these provides a non-specific cellular disease resistance mechanism?

a) Macrophages
b) T lymphocytes
c) B lymphocytes
d) Memory B cells
e) Stratified squamous epithelium

A

Answer: a

609
Q

Which anti-microbial substances reduce viral replication (in uninfected cells)?

a) Transferrins
b) Perforins
c) Complement proteins
d) Defensins
e) Interferons

A

Answer: e

610
Q

Which anti-microbial substances promote cytolysis, phagocytosis and inflammation?

a) Transferrins
b) Perforins
c) Complement proteins
d) Defensins
e) Interferons

A

Answer: c

611
Q

Which cell kills infected body cells and tumor cells?

a) Natural killer cells
b) Perforins
c) platelets
d) Mucus
e) Antimicrobial proteins

A

Answer: a

612
Q

Which of the following is NOT a sign of inflammation?

a) Redness
b) Pain
c) Heat
d) Mucus production
e) Swelling

A

Answer: d

613
Q

Which of the following intensifies the effect of interferons and promotes the rate of repair?

a) Complement proteins
b) Perforin
c) Fever
d) Macrophages
e) Natural killer cells

A

Answer: c

614
Q

Which does NOT induce vasodilation and permeability (increased fluid flow) to an infection site?

a) Histamines
b) Kinins
c) Perforin
d) Leukotrienes
e) Complement

A

Answer: c

615
Q

When B and T cells are fully developed and mature, they are described as being

a) Immunocompetent
b) Pluripotent stem cells
c) Primary lymphatic cells
d) Specifically promoted
e) Germ cells

A

Answer: a

616
Q

Which induces the production of a specific antibody?

a) Phagocytosis
b) Antigen
c) Antibody
d) Defensin
e) Immunoglobulin

A

Answer: b

617
Q

Which stimulates an immune response ONLY when it is attached to a large carrier molecule?

a) Epitope
b) Antigen
c) Hapten
d) MHC antigen
e) CD8

A

Answer: c

618
Q

Genetic recombination generates diversity in what part (s) of the immune system?

a) Antigen receptors
b) MHC antigen
c) Hapten
d) MHC antigen and antigen receptors
e) Epitopes

A

Answer: d

619
Q

Which class of cells includes macrophages, B cells and dendritic cells?

a) Antigen presenting cells
b) Primary lymphocytes
c) T cells
d) RBC
e) Epitope cells

A

Answer: a

620
Q

To become activated, which requires being bound to a foreign antigen AND simultaneous costimulation?

a) B Cell
b) T Cell
c) Interferon
d) MHC antigen
e) Antigen presenting cell

A

Answer: b

621
Q

Which cells display CD4 proteins and interact with MHC Class II antigens?

a) Cytotoxic T cells
b) Helper T Cells
c) Memory T Cells
d) MHC antigens
e) B cells

A

Answer: b

622
Q

Which T cell toxin fragments DNA?

a) Perforin
b) Tumor antigen
c) Interferons
d) Lymphotoxin
e) Toxin T

A

Answer: d

623
Q

Which class of antibodies is mainly found in sweat, tears, breast milk and GI secretions?

a) IgG
b) IgA
c) IgM
d) IgD
e) IgE

A

Answer: b

624
Q

Which leads to inflammation, enhancement of phagocytosis and lysis of microbes?

a) Classical complement system
b) Alternative complement system
c) Apoptosis
d) Classical and Alternative complement systems
e) Hapten activation

A

Answer: d

625
Q

Which action makes microbes more susceptible to phagocytosis?

a) Opsonization
b) Cytolysis
c) Inflammation
d) Complement
e) Hybridoma

A

Answer: a

626
Q

Which is an inactive, self responsive cell?

a) Deleted cell
b) Hybridoma cell
c) Epitopic cell
d) Anergy cell
e) Natural killer cell

A

Answer: d

627
Q

The inability of the immune system to protect the body from a pathogen causes

a) immunodeficiency diseases
b) allergy
c) autoimmune disease
d) transplantations
e) graft

A

Answer: a

628
Q

An acute allergic response can lead to:

a) transplantation
b) retroviruses
c) anaphylactic shock
d) passive immunity
e) active immunity

A

Answer: c

629
Q

Natural exposure to an infectious agent leads to:

a) Passive immunity
b) Active immunity
c) Both of these choices
d) None of these choices

A

Answer: b

630
Q

Which class of antibodies indicates a recent invasion?

a) IgA
b) IgE
c) IgM
d) IgD
e) IgG

A

Answer: c

631
Q

Which is the most variable cell in the immune system?

a) Natural killer cell
b) Monocyte
c) RBC
d) Lymphocyte
e) Macrophage

A

Answer: d

632
Q

The primary response will peak how many days after an exposure?

a) 1 day or less
b) 2–7
c) 10–17
d) 20–30
e) Over a month

A

Answer: c

633
Q

Which type of immunity defends against any type of invader?

a) Nonspecific
b) Specific
c) Cell mediated
d) Antibody mediated immunity
e) None of these choices

A

Answer: a

634
Q

The ability of an antigen to react specifically with the antibodies or cells it has provoked is called

a) Specificity
b) Immunogenicity
c) Reactivity
d) Epitopes
e) Immune Response

A

Answer: c

635
Q

Which is a small hormone that can stimulate or inhibit many normal cell functions?

a) Enzyme
b) Kinins
c) Cytokine
d) MHC
e) Leukocyte

A

Answer: c

636
Q

Which type of adaptive immunity will result from intravenous injection of immunoglobulins?

a) naturally acquired active immunity
b) naturally acquired passive immunity
c) artificially acquired active immunity
d) artificially acquired passive immunity
e) None of these choices

A

Answer: d

637
Q

Which type of adaptive immunity will result from mother-to-baby IgA transfer via breast feeding?

a) naturally acquired active immunity
b) naturally acquired passive immunity
c) artificially acquired active immunity
d) artificially acquired passive immunity
e) None of these choices

A

Answer: b

638
Q

Natural passive immunity is associated with which of the following?

a) Vaccination
b) Exposure to a microbe resulting in antibody formation c) Receiving booster shots
d) Transfer of IgG from mother to fetus
e) Intravenous injection of antibodies

A

Answer: d

639
Q

Which cells increase the permeability of blood vessels by releasing histamine?

a) neutrophils
b) eosinophils
c) lymphocytes
d) mast cells
e) macrophages

A

Answer: d

640
Q

Which cytokine released by macrophages acts on the hypothalamus to raise the body temperature during fever?

a) Interleukin-1
b) Interleukin-2
c) Interleukin-4
d) Gamma interferon
e) Perforin

A

Answer: a

641
Q

Which immunoglobulin is a pentamer?

a) IgG
b) IgM
c) IgD
d) IgA

A

Answer: b

642
Q

Antigens that induce an allergic reaction are called

a) lymphotoxin
b) perforin
c) granulysin
d) interleukin-1
e) allergen

A

Answer: e

643
Q

Which cell is considered to be the most important cell in the immune system?

a) Cytotoxic T Cells
b) B lymphocytes
c) T Helper cells
d) Eosinophils
e) macrophages

A

Answer: c