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CC HARR > FINALS REVIEWER > Flashcards

FINALS REVIEWER Flashcards

1
Q

Essential cofactor for several oxidase enzymes

A

Molybdenum

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2
Q

Cofactor in glutathione peroxidase

A

Selenium

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3
Q

: can substitute for methionine as essential amino acid

A

Selenomethionine

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4
Q

Produced by both normal & abnormal prostate cells

A single test w/ mildly elevated PSA levels may not be significant

A

PSA

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5
Q

Multiple myeloma

A

PAP

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6
Q

hepatocellular CA

A

AFP

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7
Q

Prolactin inhibitor

A

dopamine.

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8
Q

2nd portion of the menstrual cycle

A

Luteal phase

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9
Q

Leydig cells

A

LH

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10
Q

Sertoli cells

A

FSH

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11
Q

Pyramid-shaped glands

A

Adrenal Glands

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12
Q

Secreted in circadian fashion - Increased during sleep ; Lowest at 10am to 12mm

Secreted in pulsatile fashion

A

PROLACTIN

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13
Q

Hyperaldosteronism

  • Decreased
  • Increased
A

Sodium and chloride, Cortisol, Urinary steroids

ACTH

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14
Q

Dexamethasone Suppression

Cushing’s syndrome:

A

increased cortisol (not suppressed)

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15
Q
  • Malignant tumor of adrenal medulla seen in children which may lead to abdominal mass
A

Neuroblastoma

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16
Q

is best for screening test of pheochromocytoma and urinary VMA and HVA

A

urinary metanephrine

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17
Q

Zona fasciculata (middle)

A

CORTISOL

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18
Q

Catecholamines:

A

Epinephrine,norepinephrine and dopamine

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19
Q

– metabolite of dopamine

A

Homovanillic acid (HVA)

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20
Q

– epinephrine metabolite

A

Metanephrines and Vanillylmandelic acid (VMA)

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21
Q

delta cells -

A

somatostatin

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22
Q

F cells –

A

pancreatic polypeptide

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23
Q

Secondary sexual characteristics

A

Estradiol

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24
Q

Most potent naturally occurring estrogen

A

Estradiol

25
Q

Strongly bound to SHBG

A

Estradiol

26
Q

Metabolite of estradiol

A

Estrone/

27
Q

Circulate almost exclusively bound to albumin

A

Estrone/

28
Q

Increased in obese, post-menopausal women

A

Estrone

29
Q

Increased during fetal dev’t

A

Estriol

30
Q

gnancy

A

Estriol

31
Q

“crack”

A

Cocaine

32
Q

BARBITURATES Low doses:

A

drowsiness

33
Q

BARBITURATES Toxicity:

A

depression

34
Q

BARBITURATES Higher doses :

A

anesthesia

35
Q

BARBITURATES Very high doses:

A

stupor,

36
Q

have been implicated in cases of drug-facilitated sexual assaults, “date-rape” drugs

A

Rohypnol, GHB, and ketamine

37
Q

for research only; no approved medical use

A

I

38
Q

Rx drugs: special prescription; unrefillable

A

II

39
Q
  • available by prescription; may have 5 refills in 6 months
A

III, IV

40
Q

over the counter

A

V

41
Q

• begins to form during second trimester and continues to accumulate until birth • provides evidence of maternal drug use anytime during the last two trimesters

A

Meconium

42
Q

prior drug use may be detected for several months

A

Hair

43
Q

monitoring of drug use in correctional institutions

A

Sweat

44
Q

ultrafiltrate of plasma

A

Saliva

45
Q

sample of choice

A

Urine

46
Q

represents transient passage of the drug thru the circulation

A

Blood

47
Q

Legally intoxicated

A

100 mg/dl

48
Q

Moderately severe poisoning

A

150-200 mg/dL

49
Q

loss of inhibition and slight disturbances in equilibrium and coordination

A

150-200 mg/dL

50
Q

Fatal dose: 300-400 ml

A

ETHANOL

51
Q

Wood alcohol

A

METHANOL

52
Q

Glycolic acid

A

ETHYLENE GLYCOL

53
Q

Metabolized into acetone, CO, & H2O

A

ISOPROPYL ALCOHOL

54
Q

Binds to hemoglobin to form CARBOXYHEMOGLOBIN (cherryred)

A

CARBON MONOXIDE

55
Q

• Binds to ferric ion

A

CYANIDE

56
Q

Rodenticides, weed killers, insecticides

A

ARSENIC

57
Q

• Acute poisoning common in young children

A

IRON

58
Q

• Interfere with neurotransmission (acetylcholine)

A

ORGAN HOSPRATE AND CARBAMATES

CC HARR (3 decks)

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