fungi Flashcards
true pathogens
cutaneous, subcutaneous, systemic
Saprophytic
Obtain nourishment from dead organic matter
Cell walls
Fungal cell walls formed primarily of chitin
Bacteria have walls made of peptidoglycan
Fungi are not affected by antibiotics
Fungal cell walls contain ergosterol
Human cells do not contain ergosterol
Antifungals do not kill human cells
cutaneous fungi
Trichophyton species
subcutaneous fungi
sporothrix schenckii
systemic fungi
Blastomyces dermatitidis, Histoplasma capsulatum
opportunistic fungi
Aspergillus fumigatus, Candida albicans, Pneumocystis jiroveci
Trichophyton species
cutaneous fungi; Itching, scaling skin patches that become inflamed and weepy; Defining characteristic = ability to use keratin as a source of nutrition
Sporothrix schenckii
subcutaneous fungi; granulomatous ulcer at puncture site (rose thorn disease!!), secondary lesions may be produced along draining lymphatics
Blastomyces dermatitidis
systemic fungi; enter lungs, in lungs make thick yeast cells with buds; Occurs most commonly in South Central and South Eastern U.S.
Histoplasma capsulatum
systemic fungi; get into lungs and grow into yeast cells; ONLY FUNGUS TO EXHIBIT INTRACELLULAR PARASITISM; most prevalent in central North America, especially Ohio and Mississippi River Valleys
Aspergillus fumigatus
opportunistic fungi; only is pathogenic in immunosup. and people taking broad-spectrum antibiotics; grow as molds; dust and soil, decomposing organic matter
Candida albicans
opportunistic fungi; normal flora on skin, mouth, vag, intestines; yeast overgrows when bacteria are wiped out
Pneumocystis jiroveci
opportunistic fungi; PCP pneumonia common in HIV patients; unable to culture in lab, but thought to be a yeast
