Gas transport in Blood 2 (5) Flashcards

1
Q

What are the means of CO2 transport in the blood?

A

1) solution (10%) - more than O2 because CO2 is more soluble
2) As bicarbonate (60%)
3) As carbamino compounds (30%)

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2
Q

How is bicarbonate formed?

A

CO2 diffused into red blood cells and HCO3- is switched for Cl- and hydrogen ions are buffered by haemoglobin

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3
Q

How are carbamino compounds formed?

A

The combination of CO2 with terminal amine groups in blood proteins

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4
Q

What is the Haldane effect?

A

Removing O2 from Hb increasing the ability of Hb to pick up CO2 and CO2 generated H+

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5
Q

What do the Bohr effect and the Haldane effect work in synchrony to facilitate?

A

O2 liberation and uptake of CO2 and CO2 generated H+ at tissues

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6
Q

What facilitates the removal of O2 from haemoglobin at tissue level by shifting the O2- Hb dissociation curve to the right?

A

The Bohr effect

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7
Q

How is CO2 liberated at the lungs?

A

The Hb pick-up the O2 and this weaken its ability to bind CO2 and H+

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8
Q

What is henrys law?

A

The amount of a given gas dissolve in given type and volume of liquid at a constant temp, is proportional to the partial pressure of the gas in equilibrium with the liquid

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