general Flashcards

1
Q

What needs to be considered in creatinine interpretation?

A

Muscle mass

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2
Q

What increase in creatinine represents a 50% drop in eGFR

A

Doubling

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3
Q

Trimethoprim increases creatinine but not eGFR because?

A

Directly inhibiting creatinine excretion

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4
Q

High bilirubin causes?

A

Abnormally low serum creatinine

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5
Q

Urea is affected by?

A

High protein meal, corticosteroids

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6
Q

Urea is increased by?

A

High protein meal, corticosteroids, ccf, GIT bleeding

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7
Q

Urea is decreased by?

A

Muscle wasting, protein malnutrition, cirrhosis

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8
Q

Creatinine is decreased by?

A

Muscle wasting, cirrhosis

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9
Q

Positive leukocyte esterase on UA represents?

A

3 white cells per high powered field

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10
Q

Normal urine has how many red cells per high powered field?

A

3

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11
Q

Strict vegetarians have a high or low pH urine

A

High

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12
Q

Which bacteria split urea?

A

Proteus and certain psuedomonas species

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13
Q

Glucose starts being excreted at what bsl

A

10 (in normal people)

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14
Q

Positive ketones means?

A

Starvation, dka, salicylate toxicity, isopropyl alcohol intoxication

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15
Q

False positive red cell on dipstick?

A

Chloroquine, rifampicin

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16
Q

What can cause interstitial nephritis?

A

Abx, NSAIDs, PPIs (all sterile pyuria and low grade proteinuria)

17
Q

What can cause sterile pyuria?

A

Kidney transplant rejection, interstitial nephritis, renal calculi

18
Q

Eosinophils in urine =

A

Rapidly progressive gn, infection, interstitial nephritis

19
Q

Red cells released from glomerulus are

A

Acanthocytes, red cell casts

20
Q

Hyaline casts are

A

Tamm-horsfall protein (made in loop of Henle). Dehydration with low flow rates

21
Q

Granular casts mean

A

An insult to the nepron

22
Q

White cell casts are found in

A

Interstitial nephrits, pyelonephritis, glomerulonephritis

23
Q

Calcium oxalate crystals are?

A

Envelope shaped. Most commen

24
Q

Uric acid crystals are soluble in

A

Alkaline urine

25
Q

Struvite crystals imply?

A

Chronic infection

26
Q

Normal 24 h urine protein?

A

Less than 300mg (this is very generous)