Genetics of Addiction Flashcards
1
Q
CHRNA5
A
Helps cells to detect nicotine due to having two copies
2
Q
OPRM1
A
Opioid abuse due to change in protein amt
3
Q
Per 1/2
A
Stress = more alcohol
4
Q
mGluR2
A
alcoholic chances decreased
5
Q
DRD2
A
commonly found in alcohol and cocaine addicts
6
Q
pedigrees
A
family trees
7
Q
gene
A
location on DNA that codes for proteins
8
Q
DNA
A
ATCG
9
Q
Allele
A
can vary in # or sequence of nucleotides
10
Q
proteins
A
amino acids that are determined by a sequence of alleles in mRNA
11
Q
genotype
A
two copies (one from mom and another from dad)
12
Q
chromosome
A
coiled up DNA that carries genetic info
13
Q
ADH
A
breaks down alcohol into acetaldehyde
14
Q
ALDH
A
breaks down acetaldehyde into acetate
15
Q
what does it mean when there is a less efficient form of ADH
A
increase for alcoholism because it breaks down slower = lessened effects
