Genomic Sequencing - learning outcomes/ questions Flashcards
Computer programs can be used to identify base sequences. How?
Computer programs can be used to identify base sequences by looking for sequences similar to known genes.
Comparison of genomes reveals what?
Comparison of genomes reveals that many genes are highly conserved across different organisms.
Many genomes have been what?
Many genomes have been sequenced, particularly of disease-causing organisms, pest species and species that are important model organisms for research.
The sequence of events can be determined using what?
The sequence of events can be determined using sequence data and fossil evidence.
Phylogenetics is the study of what?
Phylogenetics is the study of evolutionary history and relationships.
Molecular clocks are used to what?
Molecular clocks are used to show when species diverged during evolution.
Molecular clocks assume a what?
Molecular clocks assume a constant mutation rate and show differences in DNA sequences or amino acid sequences.
Molecular clocks assume a constant mutation rate and show differences in DNA sequences or amino acid sequences. What is the result of this?
Therefore differences in sequence data between species indicate the time of divergence from a common ancestor.
Pharmacogenetics is the use of what?
Pharmacogenetics is the use of genome information in the choice of drugs.
An individual’s personal genome sequence can be used to select the most what?
An individual’s personal genome sequence can be used to select the most effective drugs and dosage to treat their disease (personalised medicine).
