GI Drugs

Question 1

what is an example of a 5ASA drug?

Answer 1

mesalamine

used UC

Question 2

which drugs are used in Crohn’s to induce remission?

Answer 2

monotherapy with glucocorticoids (short course PO prednisolone for mild attacks, IV hydrocortisone in hospital for severe flareup)

Azathioprine or mercaptopurine may be added on to induce remission if 2 or more exacerbations in a 12-month period or the glucocorticoid cannot be tapered

Question 3

what is first line in medical management to maintain Crohn’s remission?

Answer 3

Azathioprine

Question 4

patients with eosinophilic oesophagitis with atopy may respond to which drugs?

Answer 4

• steroids
• cromoglycate
• montelukast

however, if allergen can be identified then this is preferred first

Question 5

which drug classes are used in dyspepsia for acid suppression?

Answer 5

PPI
H2 receptor antagonist

Question 6

what are examples of PPIs?

Answer 6

lansoprazole, omeprazole, pantoprazole

Question 7

what is an example of a H2 receptor antagonist?

Answer 7

ranitidine