GI Facts Flashcards
Nutrients absorbed in the jejunum
Ca, Zn, folate
Nutrients absorbed in the ileum
B12, fat sol vits, bike salt absorption
Voluminous - inflammatory or non-inflammatory?
Non-inflammatory (inflame is small vol freq stools)
Inflammatory or non-inflammatory: tenesmus?
Inflammatory
Inflammatory or non-inflammatory: severe abd pain?
Inflammatory
Inflammatory or non-inflammatory: fever
Inflammatory
Inflammatory or non-inflammatory: dehydration?
Non-inflammatory
Inflammatory or non-inflammatory: fecal leuks?
Inflammatory
Eg of inflammatory diarrhea causes?
Invasive infections, IBD, ischemia
Eg of non-inflammatory diarrhea causes?
Non-invasive infections, IBS, Rx
Osmotic or secretory: voluminous?
Secretory
Osmotic or secretory: stops or markedly decreased with fasting?
Osmotic
Osmotic diarrhea eg of causes?
Sugar substitutes, mg++laxatives, lactose intol
Eg of secretory diarrhea causes?
Infections w/enterotoxins, laxatives, NET secretagogues, crohn’s, celiac
Osmotic & secretory osmotic gap?
Osmotic - >50
secretory -
Osmotic gap eq?
290 - [2X (stool Na + stool k)]
Celiac pathophys?
Gliadin disrupts tight junction
Activ inflamm cascade
Tissue transglutaminase (tTG) alters gliadin –> T cell response
Structural disruption of mucosa