GI Hormones Flashcards

1
Q

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Gastrin

A

Stimulates - acid secretion

G cells in antrum of stomach

Small peptides, amino acids, gastric distention, vagal stimulation

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2
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CCK

A

Stimulates - gall bladder contraction, pancreatic enzyme secretion, pancreatic bicarbonate secretion, satiety
Inhibits - gastric emptying

I cells of duodenum and jejunum

Small peptides, AAs, FAs, CCK-RP, monitor peptide

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3
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Secretin

A

Stimulates - pancreatic bicarbonate secretion, biliary bicarbonate production
Inhibits - gastric acid secretion

S cells in duodenum

Acid

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4
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GIP

A

Stimulates - insulin release
Inhibits - gastric acid secretion

K cells in duodenum and jejunum

FAs, AAs, oral glucose

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5
Q

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Motilin

A

Stimulates - gastric and intestinal motility

duodenum and jejunum

Nerves

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6
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Somatostatin

A

Inhibits - GI hormone release, gastric acid secretion

D cells in GI mucosa

acid

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7
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Histamine

A

Stimulates - gastric acid secretion

ECL cells

Gastrin

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8
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VIP

A

Relaxes GI smooth muscle
Stimulates - intestinal secretion, pancreatic secretion

GI mucosa and smooth muscle

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9
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GRP

A

Stimulates - gastrin release

Gastric mucosa

Vagal stimulation

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10
Q

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Enkephalins

A

Stimulate - contraction of smooth muscle
Inhibit - intestinal secretion

GI mucosa and smooth muscle

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11
Q

Which GI hormones stimulate acid secretion

A

Gastrin

Histamine

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12
Q

What GI hormone is released from the antrum of the stomach

A

Gastrin

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13
Q

Which GI hormones inhibit gastric acid secretion

A

Secretin

GIP

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14
Q

Which GI hormones relax GI smooth muscle

A

VIP

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15
Q

Which GI hormones are going to release bicarbonate

A

CCK

Secretin

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16
Q

Oral glucose will result in the release of what GI hormone

A

GIP

17
Q

The presence of acid will result in the release of which GI hormones

A

Secretin

Somatostatin

18
Q

What affect do proteins have on CCKn

A

They protect CCK from degradation by trypsin

19
Q

Which GI hormone causes GI smooth muscle contraction?

A

Enkephalins