GI Hormones Flashcards
Actions
Site of Release
Releaser
Gastrin
Stimulates - acid secretion
G cells in antrum of stomach
Small peptides, amino acids, gastric distention, vagal stimulation
Actions
Site of Release
Releaser
CCK
Stimulates - gall bladder contraction, pancreatic enzyme secretion, pancreatic bicarbonate secretion, satiety
Inhibits - gastric emptying
I cells of duodenum and jejunum
Small peptides, AAs, FAs, CCK-RP, monitor peptide
Actions
Site of Release
Releaser
Secretin
Stimulates - pancreatic bicarbonate secretion, biliary bicarbonate production
Inhibits - gastric acid secretion
S cells in duodenum
Acid
Actions
Site of Release
Releaser
GIP
Stimulates - insulin release
Inhibits - gastric acid secretion
K cells in duodenum and jejunum
FAs, AAs, oral glucose
Actions
Site of Release
Releaser
Motilin
Stimulates - gastric and intestinal motility
duodenum and jejunum
Nerves
Actions
Site of Release
Releaser
Somatostatin
Inhibits - GI hormone release, gastric acid secretion
D cells in GI mucosa
acid
Actions
Site of Release
Releaser
Histamine
Stimulates - gastric acid secretion
ECL cells
Gastrin
Actions
Site of Release
Releaser
VIP
Relaxes GI smooth muscle
Stimulates - intestinal secretion, pancreatic secretion
GI mucosa and smooth muscle
Actions
Site of Release
Releaser
GRP
Stimulates - gastrin release
Gastric mucosa
Vagal stimulation
Actions
Site of Release
Releaser
Enkephalins
Stimulate - contraction of smooth muscle
Inhibit - intestinal secretion
GI mucosa and smooth muscle
Which GI hormones stimulate acid secretion
Gastrin
Histamine
What GI hormone is released from the antrum of the stomach
Gastrin
Which GI hormones inhibit gastric acid secretion
Secretin
GIP
Which GI hormones relax GI smooth muscle
VIP
Which GI hormones are going to release bicarbonate
CCK
Secretin