GI Phys Flashcards
Potent stimulators of the hormone that controls gastric motility.
Gastrin. Phenylalanine and tryptophan
cells located here control the growth of the gastric mucosa?
G cells. Antrum of stomach
Hormone released by these cells act on neural muscarine pathways in response to fatty acids?
I cells in duodenum/jejunum release CCK to cause pancreatic and gallbladder secretion
The duodenal cells a hormone in response to acid and fatty acids. MoA?
S-cell. Secretin triggers bile and pancreatic HCO3 secretion to neutralize acid.
Without this hormone, pancreatic enzymes would be denatured to a greater degree.
Secretin triggers bile and pancreatic HCO3 secretion to neutralize acid.
Name and Location of cell bodies of Inhibitory hormone that prevents absorption of nutrients?
D-cells in pancreatic islets and GI mucosa release Somatostatin
Hormone that decreases insulin and glucagon release controlled by?
Somatostatin. Increased with acid. Decreased by vegal stimulation
Oral intake of glucose induces more rapid insulin release than IV glucose because of this hormone that is released by these cells located where?
K cells in duodenum/jejunum release GIP that increases insulin release
This GI hormone has exocrine and endocrine function
GIP:
exocrine: decreass gastric H secretion
endocrine: increases release
Distention and vegal input causes the release of this hormone from this location that causes relaxation of intestinal SMC and sphincters
Vasoactive intestinal polypeptide from PSNS ganglia in sphincters, gallbladder, small intestine.
Non-alpha and non-beta cell pancreatic tumor?
VIPoma
Pt with Watery diarrhea, hypoK and achlorhydria?
VIPoma
NO - decreased secretion results in?
alchalasia - Increased LES tone
Name the agonist this receptor that leads to migrating motor complexes?
Erythromycin - motilin agonist
Cells that are attacked in pernicious anemia produce less of this factor, leading to this?
parietal cells of stomach. Damage decreases intrinsic factor leading to B12 deficiency
