GI Protectant

Question 1

GI Protectant Drug Names

Answer 1

Sucralfate

Question 2

GI Protectant Therapeutic Actions

Answer 2

• Forms an ulcer-adherent complex at duodenal ulcer sites, protecting the sites against acid, pepsin, and bile salts

Question 3

GI Protectant Indications

Answer 3

• Promote ulcer healing

Question 4

GI Protectant Contraindications and Cautions

Answer 4

Contraindications:
• Known allergy
• Renal Failure

Caution:
• Pregnancy or lactation

Question 5

GI Protectant DDI

Answer 5

DDI:
• Aluminum salts
• Phenytoin, fluoroquinolone, or penicillamine

Question 6

GI Protectant Adverse Effects

Answer 6

•	GI effects:
-	Constipation, diarrhea, nausea, indigestion, gastric discomfort, dry mouth
•	CNS effects:
-	Dizziness
-	Sleepiness
-	Vertigo

Question 7

GI Protectant:

Assessment

Answer 7

Hx: Allergy, lactation and pregnancy, renal dysfunction or dialysis
Physical: vital signs, lesions in or mucosa or rash, orientation, affect, and reflexes, abdominal, bowel pattern/ changes(baseline)
Labs: monitor results

Question 8

GI Protectant:

Diagnosis

Answer 8

Dx:

• Diarrhea
• Risk for constipation
• Imbalanced nutrition: less than body requirements
• Disturbed sensory perception (kinesthetic)
• Deficient knowledge regarding drug therapy

Question 9

GI Protectant:

Implementation

Answer 9

Implementation:
• Administer the drug on an empty stomach 1 hour before or 2 hours after meals and at bedtime
• Monitor the patient for GI pain
• Administer antacids or antibiotics, if ordered, between doses of sucralfate, not within 30 minutes of a sucralfate dose
• Provide comfort and safety measures
• Provide frequent mouth care including sugarless lozenges
• Ensure ready access to bathroom facilities
• Institute bowel training as needed
• Provide small, frequent meals
• Provide thorough patient teaching

Question 10

GI Protectant:

Evaluation

Answer 10

Eval:
Response to the drug 
Adverse effects
 Effectiveness of comfort measures
Compliance with regimen
Effectiveness of teaching plan