Glucose 10%

Question 1

What is the generic name of glucose 10%?

Answer 1

Glucose monohydrate

Question 2

What type of medication is glucose 10%?

Answer 2

Principle energy source for body cells, especially the brain.

Question 3

What is the route, onset, peak and duration of glucose 10%?

Answer 3

• Route: IV
• Onset: 30sec
• Peak: 30sec
• Duration: Dependent on the severity of the hypoglycemic episode.

Question 4

What are the uses/indications of glucose 10%?

Answer 4

Hypoglycemia: when BGL < 4mmol & decreased LOC.

Newborn resuscitation: When BGL < 2.6mmol.

Question 5

What are the adverse effects of glucose 10%?

Answer 5

• Tissue necrosis if extravasated from vein occurs.
• May aggravate brain damage in head injuries and strokes
• May precipitate Wernicke’s Encephalopathy in alcoholics with a thiamine deficiency.

Question 6

What are the contraindications of glucose 10%?

Answer 6

Nil for NSW Ambulance

Question 7

What is the preparation and dosage of Glucose 10%?

Answer 7

• Preparation: 10% - 50g per 500mL bag.
• For Hypoglycemia:
  
  • < 10yo: 0.5g/kg bolus (max bolus 15g)
    
    • Repeat: whilst indicated
    • Max dose: no maximum
  • 10yo+: 15g bolus
    
    • Repeat: whilst indicated
    • Max dose: no maximum
• For Newborn Resuscitation:
  
  • Newborn: 0.25g/kg bolus (max bolus 15g)
    
    • Repeat: whilst indicated
    • Max dose: no maximum

Note: IV line must be flushed with 10mL NaCl at the completion of administration or prior to the administration of other medications.