Gynaecomastia Flashcards
1
Q
What?
A
Abnormal amount of breast tissue in males and is usually caused by an increased oestrogen:androgen ratio
2
Q
Causes
A
Physiological: normal in puberty Syndromes with androgen deficiency: Kallman's, Klinefelter's Testicular failure e.g. mumps Liver disease Testicular cancer e.g. seminoma secreting hCG Ectopic tumour secretion Hyperthyroidism Haemodialysis Drugs
3
Q
Drug causes
A
Spironolactone (most common) Cimetidine Digoxin Cannabis Finasteride Gonaderolin analogues e.g. Goserelin, buserelin Oestrogens, anabolic steroids
4
Q
Very rare drug causes
A
Tricyclics Isoniazid Calcium channel blockers Heroin Busulfan Methyldopa
