Haem-oncology

Question 1

Symptoms specific to ALL

Answer 1

CNS symptoms

Question 2

Sign specific to AML

Answer 2

Gum hypertrophy

Question 3

Investigations for ALL

Answer 3

Bloods (FBC), Blood film, CXR, LP, Bone marrow biopsy

Question 4

Management of leukaemia

Answer 4

Transfusions, Chemotherapy

Question 5

Symptoms of acute leukaemia

Answer 5

Anaemia, Bleeding, Infections

Question 6

Signs of leukaemia

Answer 6

Hepatomegaly, Splenomegaly, Lymphadenopathy

Question 7

Investigation for leukaemia

Answer 7

Bloods, Blood film, Bone marrow biopsy,

Question 8

Specific management for CML and why

Answer 8

Imatinib - works on philadelphia chromosome

Question 9

Symptoms of chronic leukaemia

Answer 9

Aneamia, Infection, Bleeding, weight loss, Fever, Sweating

Question 10

Risk factors for lymphoma

Answer 10

Immunodeficiency, Toxins, Infections (EBV, H Pylori, HTLV-1)

Question 11

Symptoms of lymphoma

Answer 11

Anaemia, Bleeding, Infections, Weight loss, Fever, Night sweats, SVCO, Pleural effusion, Bulk obstruction

Question 12

Investigations for lymphoma

Answer 12

Bloods (FBC, LFTs, LDH, Urate, Ca, ESR), Blood film, Node biopsy, Bone marrow biopsy, PET scan

Question 13

Disease in which reed-sternberg cells are seen

Answer 13

Hodgkin’s lymphoma

Question 14

Types of non-hodgkin’s lymphoma

Answer 14

High and Low

Question 15

Symptoms of myeloma

Answer 15

Anaemia, Infections, Bleeding, Renal impairment, Bone disease, Hypercalcaemia

Question 16

Investigations for myeloma

Answer 16

Bloods (FBC, U+Es, ESR, PV), Urinary electrophoresis, X-ray

Question 17

Management of myeloma

Answer 17

Transfusions, Epo, Ig Infusion, Bisphosphonates, Chemotherapy, Radiotherapy