Haematology

Question 1

Name the three components of Virchow’s Triad of Thrombus formation.

Answer 1

Change in blood flow
Change in the vessel wall
Change in the blood contents

Question 2

What blood clotting factor is missing in Haemophilia A

Answer 2

Factor VIII (8)

Question 3

Which score is used in stratifying the risk of DVT (Deep Vein Thrombosis)?

Answer 3

Well’s Score

Question 4

Name two Factor Xa (Factor Ten A) inhibitors used in the treatment of venous thromboembolic events.

Answer 4

(1) Rivaroxaban

(2) Apixaban

Question 5

Which Vitamin does warfarin antagonise?

Answer 5

Vitamin K

Question 6

Name 4 of the 10 aspects of the Wells Score for Deep Vein Thrombosis.

Answer 6

(1) Active cancer (treatment or palpitation within six months) +1
(2) Bedridden recently >3 days or major surgery within 12 weeks +1
(3) Calf Swelling >3cm compared to other leg (measured 10cm below the tibial tuberosity +1
(4) Collateral (nonvaricose) superficial veins present +1
(5) Entire leg swollen +1
(6) Localised tenderness along the deep venous system +1
(7) Pitting oedema confined to symptomatic leg +1
(8) Parslysis, paresis or recent plaster immobilisation of the lower extremity +1
(9) Previously documented DVT +1
(10) Alternative diagnosis to DVT as likely or more likely -2