Haematology

Question 1

What does Cryoprecipitate contain?

Answer 1

factor VIII, fibrinogen, von Willebrand factor and factor XIII

Question 2

Symptoms of multiple myeloma?

Answer 2

CRAB:

C = calcium (elevated), R = renal failure, A = anemia, B = bone lesions

Question 3

Haemarthroses is a sign of?

Answer 3

Haemophillia

Question 4

CLL can transform into which type of cancer?

Answer 4

Non-Hodgekin’s (Richter’s transformation)

Question 5

What is Coomb’s test used for?

Answer 5

To confirm autoimmune haemolytic anaemia.

The indirect test is typically only used for Rhesus haemolytic disease of the newborn.

Question 6

Reed Sternberg cells is characteristic of…

Answer 6

Hodgkin’s disease

Question 7

‘tear-drop’ poikilocytes on blood film indicates

Answer 7

Myelofibrosis

Question 8

Howell-Jolly bodies indicate

Answer 8

Post-splenectomy

Question 9

In alcoholic liver disease do they get thrombocytopenia or thrombocytosis?

Answer 9

thrombocytopenia

Question 10

What is an aplastic crisis in scd?

Answer 10

caused by infection with parvovirus

sudden fall in haemoglobin

Question 11

What novel anticoagulant do you give pts with renal impairment

Answer 11

Apixaban

Question 12

Bite and blister cells are typical of the blood film in…

Answer 12

G6PD deficiency

Question 13

in G6PD deficiency avoid which drugs?

Answer 13

Some drugs causing haemolysis
anti-malarials: primaquine
ciprofloxacin
sulph- group drugs: sulphonamides, sulphasalazine, sulfonylureas