Heart events/Thrombin Flashcards
Antithrombin
Heparin
Fibrinolysis
inhibits thrombin and other factors.
released by basophils and mast cells, accelerates actions of antithrombin
when the fibrin clot is broken down by plasmin enzyme. Can measure the fibrin degradation products.
Systole
Diastole
Pressure reservoirs
when the heart muscles are contracting. (120mmHg)
when the heart muscles relax
during diastole large and medium elastic arteries maintain the blood flow
ECG
P- wave
QRS complex
T-wave
Q-T interval
electrocardiogram. Many action potentials of the heart
atrial depolarization and contraction (p to p waves should be 80ms)
spread of signal from bundle of his through to purkinje fibres. Ventricle depolarization and contraction. (atrial repolarization and relaxing is masked as a. potentials in the ventricles at this time are bigger
ventricle repolarization and relaxation
time from start of v. contraction to end of relaxation
Cardiac output
Heart rate
Stroke volume
Chronotropic effect
volume of blood ejected by each ventricle per minute
number of contractions per minute
volume of blood ejected by each ventricle per minuet
an effect on heart rate. (e.g. noradrenaline, adrenaline and glucagon all have +ve chronotropic effects, acetylcholine has -ve effects.)
Tachycardia
Bradycardia
EDV (end diastolic volume)
ESV (end systolic volume)
fast heart rate
slow heart rate
volume of blood in the ventricles at the end of diastole
volume of blood in the ventricles at the end of systole. (residual blood)
Contractibility
Inotropic effect
Preload
Afterload
contractile ability of cardia muscle at a given preload
something that affects contractibility. (SNS and adrenaline have + effects, PNS and acetylcholine have – effects.)
degree of filling heart. Relies on central venous pressure/venous return.
pressure of opposing ejection of blood, influenced by blood vessel tone
Hypotension
Hypertension
too low BP
too high BP
