Heart Failure Treatment

Question 1

What are the 4 pillars of therapy in heart failure?

Answer 1

• Angiotensin receptor-neprilysin inhibitors (ARNIs)
• Beta blockers
• Mineralcorticoid receptor antagonists (MRAs)
• Sodium-glucose co-transporter 2 inhibitors (SGLT2i)

Question 2

What is quadruple therapy (specifically in relation to heart failure) ?

Answer 2

Using a combination of 4 drug classes to manage heart failure

Question 3

What two drugs can be used to improve the symptoms of heart failure?

Answer 3

• Digoxin
• Frusemide

Question 4

How should beta blockers be given in heart failure?

Answer 4

Started on a low dose and getting up-titrated to the highest dose that can be tolerated

Question 5

When is a combination of hydralazine and nitrates used in heart failure?

Answer 5

When ACEi or ARBs are not tolerated

Question 6

What SGLT2i inhibitor is commonly used in heart failure?

Answer 6

Ivabradine