Hema platings (2)

Question 1

Function of the HMP:
a. Prevents the oxidation of the Hgb molecule
b. Synthesize reduced glutathione
c. Both A and B
d. Neither A nor B

Answer 1

Both A and B

Question 2

True about Bohr effect:
d. Neither A nor B
Both A and B
True about Bohr effect:
a. It is a reaction that helps maintaining blood pH normal
b. It is reaction that includes the oxygen and Hydrogen binding to the
HGB molecule.
c. Both A and B
d. Neither A nor B

Answer 2

Both A and B

Question 3

Normally 100% 02 saturation of HGB occurs at what oxygen
pressure?
a. 26 mmHg
b. 27 mmHg
c. Both A and B
d. Neither A nor B

Answer 3

Neither A nor B

Question 4

Which is False?
a. PNH is a condition where there is a deficiency of GPl-linked RBC
membrane protein.
b. Hereditary spherocytosis is caused by deficiency of protein band 4.1
c. Both A and B
d. Neither A nor B

Answer 4

b. Hereditary spherocytosis is caused by deficiency of protein band 4.1

Question 5

The 2,3, DPG is synthesized specifically at:
a. Rapaport-Luebering pathway
b. Hexose Monophosphate pathway
c. Both A and B
d. Neither A nor B

Answer 5

Rapaport-Luebering pathway

Question 6

Which will cause the 02 curve to the left?
a. Low 2,3DPG
b. Presence of Hgb Kansas
c. Both A and B
d. Neither A nor B

Answer 6

Low 2,3DPG

Question 7

Which will cause 02 curve to the right?
a. HgbF
b. Carboxyhemoglobin
c. Both A and B
d. Neither A nor B

Answer 7

Neither A nor B

Question 8

Which of this cause shift to the right of oxygen dissociation curve?
a. Hypoxia
b. Hyperventilation
c. Both A and B
d. Neither A nor B

Answer 8

Hypoxia

Question 9

It will cause a shift to the Right in oxygen dissociation curve:
a. Low blood pH
b. Hypothermia
c. Both A and B
d. Neither A nor B

Answer 9

Low blood pH

Question 10

Enzyme that is part of the EMP of red cell metabolism:
a. Glucose 6 phosphate dehydrogenase
b. Pyruvate kinase
c. Both A and B
d. Neither A nor B

Answer 10

Pyruvate kinase

Question 11

Which of this increases the binding of oxygen molecule to the HGB?
a. high 2,3 DPG
b. Methemoglobin formation
c. Both A and B
d. Neither A nor B

Answer 11

Neither A nor B

Question 12

Enzyme involved in the terminal or 3rd phase of glucose metabolism under the EMP pathway
a. Pyruvate kinase
b. Lactate dehydrogenase
c. Both A and B
d. Neither A nor B

Answer 12

Both A and B

Question 13

p50 or 50% oxygenation of Hgb normally occurs when the partial pressure of O2 reaches:
a. 19 mmHg
b. 27 mmHg
c. Both A and B
d. Neither A nor B

Answer 13

27 mmHg

Question 14

Haldane effect is:
a. Relative binding of CO2 to unoxygenated Hgb and oxygenated Hgb
b. It is the process that prevents the rebinding of CO2 to the Hgb within
the lung tissue.
c. Both A and B
d. Neither A nor B

Answer 14

Both A and B

Question 15

Deficiency of this/ese protein/s may cause spherocytic formation of red cells
a. Spectrin
b. Protein band 41
c. Both A and B
d. Neither A nor B

Answer 15

Spectrin