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Ecn > Hemato > Flashcards

Hemato Flashcards

1
Q

Facteurs mauvais pronostics LLC 6

A 
11q ou 17p
Mutation p53
ZAP70 ou CD38
Pas de mutation du gene d'Ig
TD
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2
Q

Bilan syndrome myélodysplasique

A

Epo
Ferritine
Caryotype medullaire
B9-b12

Cytopenies 10 / 100 / PNN 1,8

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3
Q

Caryotype myelome

A

Chromosome 13
T(4,14)
17p

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4
Q

Complications splénomégalie

A 
Hypersplenisme 
Splenectomie
Rupture de rate
Infarctus splenique
SAM
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5
Q

Signes de gravité d’un purpura 8

A

Sepsis, sepsis grave
Syndrome méningé, signes neuro centraux
Hemorragies au FO
Purpura necrotique et/ou ecchymotique et/ou extensif
Purpura des muqueuses et / ou syndrome hémorragique : bulles hemorragiques, hemorragie conjonctivale, epistaxis, gingivorragies, hematurie macroscopique
Aspect en carte de geographie
Localisation a risque de retentissement fonctionnel
CIVD
Prises : AAP ou anticoagulant

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6
Q

Anémie microcytaire et fer serique augmenté

A 
Smd
Carence en b6
Inflammation
Thalassemie
Saturnisme
Carence martiale traitée
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7
Q

Criteres diagnostiques biermer 3

A

Carence en b12
Achoorhydrie ( augmentation de la gastrine)
Ac anti facteur intrinseque

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8
Q

Maladie de willebrand acquise 6

A 
Hypothyroidie
Cardiopathie valvulaire
Dysproteinemie monoclonale
Thrombocytemie essentielle
Angiodysplasie digestive 
Auto-anticorps
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9
Q

Facteurs de mauvais pronostic dans les LAM 7

A 
Age > 60 ans
Ps > 2
Secondaire
Hyperleucocytose importante
Cytogenetique: caryotype complexe, anomalies du chromosome 5-7 
Comorbidites
Reponse au tt initial
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10
Q

Facteurs pronostiques dans les LaL

A 
Age  60ans
Hyperleucocytose importante
Ps > 2
Comorbidites
Cytogenetique : hypoploidie, t° 9-22
Reponse au tt 
Envahissement neuromeningee
Lal t
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11
Q

Remission complete d’une leucemie aigue 4

A

Pas de blastes circulants
PNN > 1G/L
P >100
Blastes

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12
Q

Causes d’anémie dans la LLC 6

A 
Inflammatoire
AHAI
EAI
Hypersplenisme
Iatrogene 
Insuffisance medullaire
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13
Q

Signes de gravité d’une thrombopenie 6

A 
Purpura extensif
Bulles hemorragiques
Signes neurologiques ou cephalees intenses 
Hemorragies au fond d'oeil
Plaquettes
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14
Q

Bilan etiologique d’un syndrome mononucleosique 4

A

Serologies toxo, VIH, CMV

MNI test

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15
Q

Eosinophilie bilan 1ere intention 7

A 
EPS
EPS
IUC BHC 
VIH-vhb-vhc
Serologie toxocarose
Echo abdo RP ETT 
CRP
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16
Q

Causes d’hypereosinophilie

A 
Atopie: toujours inferieure a 1G/L
Helminthiase
Hemopathie et cancer
Iatrogene ( dont DRESS syndrome)
Vascularite : churg et strauss ++ 
Emboles de cholesterol
MICI / maladie coeliaque
Loffler / fernand vidal 
Pemphigoide bulleuse 
VIH VHC
Poumon eosinophile: medicaments, parasitose, ABPA, churg et strauss
17
Q

Paraclinique ADP cervicales

A 
Nfs-crp
Vih -ebv-cmv-toxoplasmoe
Bartonella si chat
Syphilis si risque
Biopsie si negatif
18
Q

Polyadenopathies

A

Radio pulm
Nfs-crp
Bhc
Vih-ebv-cmv-toxoplasmose

19
Q

Medicaments responsables d’agranulocytose medicamenteuse 6

A 
Clozapine
Carbimazole
Dapsone, peni G fortes doses
Deferiprone
Rituximab, sulfasalazine
Carbamazepine
20
Q

TRALI

A

Ac anti leucocytes
SDRA fébrile
P°: eviction du don si immunisation dans le systeme HLA/HNA

21
Q

Complications transfusion massive 8

A 
Hypocalcemie
Hypothermie
Hyperkaliemie
Troubles de coagulation 
Surcharge volemique
Sdra 
Hemorragie 
Hemochromatose
22
Q

Bilan prurit (7)

A 
Rp
Echo abdo
PAL-GGT
TSH
VIH VHB VHC 
NFS P
Creat
23
Q

Bilan PTI

A 
BHC
NFS P / FS
VIH VHB VHC
Creat
TSH / Ac anti TPO 
Groupe si severe
TP - TCA - fibrinogene
EPS
AAN
24
Q

PBR purpura rhumatoide

A 
Proteinurie > 0,5-1g/J
HTA
SNI
IRC
HTU macro recidivante
25
Q

Sam secondaire (3)

A

Infection
Lymphome
Led

26
Q

Thrombocytose (4) bilan

A

Ferritine
Nfs vs cro
Fs
Bilan d’hemolyse

27
Q

Bilan LLC (3)

A

Caryotype
Epp
Coombs

28
Q

Myélémie (5)

A 
Infection severe
Regeneration medullaire
Smp
Envahissement medullaire
LAM

Ecn (4 decks)

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