Hemochromatosis Flashcards
1
Q
What is hemochromatosis?
A
Excess iron storage leading to multisystem dysfunction, especially liver failure
2
Q
What is the pathogenesis of primary hemochromatosis?
A
Genetic
Ongoing gut absorption despite adequate iron stores
3
Q
What is the pathogenesis of secondary hemochromatosis?
A
High number of transfusions
Chronic hemolytic anemia
High PO intake
4
Q
What are the signs of hemochromatosis?
A
TRIVIAL liver enzyme elevation
High transferrin saturation
High serum ferritin
5
Q
What are the consequences of hemochromatosis?
A
CIRRHOSIS
High HCC risk
Diabetes
6
Q
Treatment for hemochromatosis?
A
Phlebotomy
