Histology of Muscle and the Circulatory System Flashcards

1
Q

Type of muscle cell:

  • elongated with blunted ends
  • multinucleated
  • peripheral nuclei
  • sorted in bundles or fascicles
A

Skeletal myocyte

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2
Q

Type of muscle cell:

  • elongated with branching ends
  • mononucleated or binucleated
  • central nucleus/nuclei
  • sorted in bundles or fascicles
  • with intercalated discs (zonula adherens)
A

Cardiac myocyte

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3
Q

Type of muscle cell:

  • elongated with tapered ends, spindle-shaped
  • mononucleated
  • central nucleus
  • non-striated
  • sorted in layers
A

Smooth myocyte

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4
Q

Layers of the cardiac wall

A
  1. epicardium
  2. myocardium
  3. endocardium
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5
Q

Cardiac wall layer:

  • thin layer connective tissue and fat (fat deposits seen at the sulci)
  • serves as an additional layer of protection for the heart
  • the continuation of the serous pericardium
A

Epicardium

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6
Q

Cardiac wall layer:

  • contains the muscle tissue of the heart
  • composed of the cardiomyocytes that receive nervous stimulation from the sinoatrial (SA) and atrioventricular (AV) nodes via the Purkinje fibers
A

Myocardium

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7
Q

Cardiac wall layer:

  • composed of endothelial cells that provide a smooth, non-adherent surface for blood collection and pumping and may help regulate contractility
  • thin serous membrane
  • lines the interior of the heart and valves
A

Endocardium

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8
Q

Type of artery responsible for DISTRIBUTION of blood to different organ

A

Muscular artery (or medium artery)

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9
Q

Type of artery responsible for CONDUCTING responses of pulse - to stretch in response to each pulse

A

Elastic artery (or conduit artery, or large artery)

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10
Q

Layer of blood vessel entirely made of connective tissue

  • thickest in veins
  • contains nerves that supply the vessel
  • contains nutrient capillaries (vasa vasorum) in the larger blood vessels
A

Tunica adventitia

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11
Q

Layer of blood vessel made up of circularly arranged elastic fiber, connective tissue, polysaccharide substances:

  • thickest in arteries
  • layered, in which the second and third layer are separated by another thick elastic band called external elastic lamina
  • may (especially in arteries) be rich in vascular smooth muscle, which controls the caliber of the vessel
  • veins lack the external elastic lamina, but only an internal one
A

Tunica media

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12
Q

Layer of blood vessel made up of a single layer of simple squamous endothelial cells glued by a polysaccharide intercellular matrix:

  • thinnest layer
  • surrounded by a thin layer of subendothelial connective tissue
  • with interlacing circularly arranged elastic bands called the internal elastic lamina
A

Tunica intima

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13
Q

Type of large vessel:

  • small lumen
  • thick wall
  • tunica media thickest
  • rigid
  • with internal elastic membrane
  • no valves
  • more abundant muscles and elastic tissue
  • vasa vasorum extended up to tunica media
A

Artery

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14
Q

Type of large vessel:

  • large lumen
  • thinner wall
  • tunica adventitia thickest
  • non-rigid
  • without internal elastic membrane
  • with valves (extension of tunica intima)
  • less abundant muscles and elastic tissue
  • vasa vasorum extended up to tunica intima
A

Vein

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15
Q

Type of vessel:

  • no smooth muscle
  • large amount of connective tissue at its periphery
A

Venule

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16
Q

Type of vessel:

  • with circular layer of smooth muscle in the tunica media
  • lumen slightly larger than an erythrocyte
A

Arteriole

17
Q

Type of vessel:

  • smallest of a body’s blood vessels (and lymph vessels)
  • microcirculation
  • single-cell layer thickness of endothelial lining
A

Capillary

18
Q

Type of capillary:

  • most common
  • endothelial cells form an uninterrupted lining
  • seen in muscles, nervous, connective tissue
A

Continuous capillary

19
Q

Type of capillary:

  • endothelial lining contains numerous pores (fenestrations)
  • seen in renal glomeruli
A

Fenestrated capillary

20
Q

Type of capillary:

  • endothelial lining is discontinuous
  • seen in the hepatic sinusoids
A

Sinusoidal capillary

21
Q

Cell associated with azurophilic granules

A

Neutrophil

22
Q

Basic structural and functional unit of the skeletal muscle

A

Sarcomere

23
Q

Region of the sarcomere that only contains ACTIN filaments (purely thin filament)

A

I band

24
Q

Region of the sarcomere that contains the Z lines

A

I band

25
Q

Region of the sarcomere that is does not change in length in contraction

A

A band

26
Q

Region of the sarcomere that “disappears” in contraction (area composed of purely thick filament)

A

H zone

27
Q

Cytoplasmic protein that connects the cytoskeleton of a muscle fiber to the surrounding extracellular matrix through the cell membrane; deficient in the diagnosis of Duchenne muscular dystrophy (DMD)

A

Dystrophin

(Notes:

  • sex-lined, affects only males
  • muscle wasting at age 5
  • deletion/mutation of the dystrophin gene)