Hodgkin's lymphoma Directed Reading Quiz

Question 1

Flurodeoxyglucose cannot be given to people whose blood glucose levels are:

Answer 1

200 mg/dl

Question 2

Classic Hodgkin’s lymphoma (CHL) is characterized by abnormal cells called:

Answer 2

Reed-Sternberg cells

Question 3

Which of the following statements are true
concerning pregnancy and HL?
1. Pregnancy alters the course of the disease.
2. Pregnancy does not alter survival rates.
3. Patients who are pregnant present special
diagnostic and treatment challenges

Answer 3

2 and 3

Question 4

Radiation treatment for HL involves a (an):

Answer 4

6 mV photon beam for areas above the diaphragm and 18 mV photons for areas below the diaphragm.

Question 5

The NCCN has created guidelines for radiation
therapy as:

Answer 5

part of a combined-modality treatment in CHL

Question 6

FDG-PET has not proven helpful in determining
whether treatment should be modified for
patients with HL: true or false

Answer 6

False

Question 7

Which of the following statements are true
about treatment effects for patients with HL?
1. Heart disease is a potential adverse effect.
2. Long-term survival is rare.
3. By 10 to 15 years following diagnosis,
deaths from treatment toxicities outnumber
deaths from the disease.

Answer 7

1 and 3

Question 8

Generally, __________ is used to treat earlystage
Lymphocyte Predominant HL.

Answer 8

Radiation only

Question 9

Refractory or relapsed HL is best treated
with a protocol that involves:

Answer 9

high-dose chemotherapy followed by autologous peripheral blood stem cell transplant.

Question 10

__________ is a long-term adverse effect of
neck irradiation.

Answer 10

hypothyroidism

Question 11

Hodgkin lymphoma (HL) has a cure rate of at
least 80%, depending on the disease stage and
the presence of certain risk factors. However,
cases of relapsed or refractory disease have a
cure rate approaching only _____%.

Answer 11

50

Question 12

The National Comprehensive Cancer
Network (NCCN) lists _______ among
unfavorable indicators for HL stage I and II.

Answer 12

presence of systemic symptoms

Question 13

__________ is the current gold standard in
chemotherapy treatment for every stage of HL.

Answer 13

ABVD (Adriamycin, bleomycin, vincristine, and dacarbazine)

Question 14

Elderly patients with HL who have lung problems
should not be treated with ________,
a drug that is toxic to the lungs.

Answer 14

bleomycin

Question 15

Typically, the first symptom of HL that a
patient notices is:

Answer 15

an enlarged gland in the neck.

Question 16

Patients with advanced HL and an international
prognostic score (IPS) of 4 or more commonly
are treated with:

Answer 16

BEACOPP (Doxorubicin, vinblastine, mechlorethamine, etoposide, vincristine, bleomycin, and prednisone)

Question 17

According to the NCCN treatment algorithms,
restaging with PET-CT for CHL should occur:

Answer 17

after completion of initial chemotherapy cycles, before consolidation radiation therapy.

Question 18

According to this Directed Reading, the most
detrimental effects of the MOPP protocol are
__________ and __________.

Answer 18

leukemia, sterility

Question 19

Subtotal nodal (or lymphoid) irradiation
includes which regions?

Answer 19

all areas at risk, including the spleen

Question 20

A young female HL survivor who received radiation therapy 8 years ago should take the following steps:

Answer 20

annual mammography and breast MR imaging plus monthly breast self-exams.

Question 21

Systemic, or B, symptoms for HL include
_______.

Answer 21

drenching night sweats

Question 22

At the completion of treatment, a CT scan
shows a hepatic lesion 2 cm in diameter, with
an uptake equal to that of the liver. This lesion
is negative for lymphoma: true or false?

Answer 22

False

Question 23

A __________ should be part of a diagnostic
workup for HL.

Answer 23

contrast-enhanced diagnostic CT of the chest, abdomen and pelvis.

Question 24

Radiation dose for the Stanford V protocol
in bulky disease is:

Answer 24

36 Gy

Question 25

Compared with CHL, lymphocyte-predominant
HL (LPHL) is:

Answer 25

less aggressive

Question 26

How much time should elapse before performing
a PET scan after radiation treatments for HL?

Answer 26

8 weeks