Hormonas independientes del eje hipotalamo- hipofisis (paratiroides) Flashcards

1
Q

cuales son estas hormonas

A
  • Paratiroides
  • Hormonas pancreáticas (insulina y
    glucagón)
  • Melatonina
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2
Q

donde se genera la hormona paratiroidea PTH

A

células principales de la glándula paratiroides.

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3
Q

Cuando se incrementa la PTH

A

por disminucion de calcio

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4
Q

la PTH es percibida por que receptores…

A

proteina G

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5
Q

altas concentraciones de calcio (produce ácido araquidónico) y de vitamina D reducen la síntesis y secreción de la PTH. ¿Que tipo de feedback es?

A

retroalimentacion negativa

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6
Q

Funcion PTH

A
  • activa osteoclastos
    • reabsorcion renal de calcio
  • Conversion de vitamina D a du forma activa (calcitriol)
    • absorcion de calcio en tracto gastrointestinal, el calcitriol hace que mas calcio entre a a celula
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7
Q

hiperparatiroidismo consecuencia

A

hipercalcinemia

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8
Q

causa hipercalcinemia

A

adenoma paratiroideo

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9
Q

Hipoparatiroidismo consecuencia

A

hipocalcinemia

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10
Q

sintomas hipocalcinemia

A

alteraciones neuromusculares (espasmos
musculares, tetania), arritmias cardiacas

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11
Q

causas hipocalcinemia

A
  • Extripacion quirurgica de paratiroides
  • Sindrome Digeorge: ausencia congenita de paratiroides y timo
  • Autoinmunidad: anticuerpos que destruyen glandula paratiroides
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