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Pharmaaaa > Hormone Of Hypothalamus And Pituitary Gland > Flashcards

Hormone Of Hypothalamus And Pituitary Gland Flashcards

1
Q

GH analog

A

Somatotropin

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2
Q

IGF-1 analog

A

Mecasermin

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3
Q

SST analog

A

Octreotide

Lanreotide

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4
Q

GH antagonist

A

Pegvisomant

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5
Q

Gonadotropin analogs

A

Follitropin
Lutropin
Menotropins
hCG/rhCG

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6
Q

GnRH analogs

A

-RELINS

Gonadorelin
Goserelin
Histrelin
Nafarelin
Triptorelin
Leuprolide
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7
Q

GnRH antagonists

A

-RELIX

Ganirelix
Cetrorelix
Abarelix
Degarelix

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8
Q

Prolactin antagonists

A

Bromocriptine
Cabergoline
Quinagolide

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9
Q

Oxytocin related

A

Oxytocin

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10
Q

Oxytocin antagonist

A

Atosiban

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11
Q

ADH antagonist

A

Tolvaptan

Conivaptan

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12
Q

ADH agonists

A

Vasopressin

Desmopressin

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13
Q

-RELIX

A

GnRH antagonists

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14
Q

-RELIN

A

GnRH analogs

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15
Q

-VAPTANS

A

ADH antagonists

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16
Q

Drug for DI

A

Vasopressin

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17
Q

Deug for SiADH

A

Vasopressin antagonist (tolvaptan, conivaptan)

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18
Q

Hormone that acts DIRECTLY on the target organ

A

Prolactin

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19
Q

Master gland

A

Hypophysis/pituitary gland

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20
Q

Hypothalamic hormone of prolactin

A

TRH

Target organ: thyroid

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21
Q

Target organ of somatostatin

A

Somatostatin>inhibit GH secretion>BREAST

22
Q

Receptor of peptide hormones

A

Cell membrane receptors

23
Q

Enumerate peptide hormones

A

ALL hypothalamic and pituitary hormones

24
Q

Receptors of steroid hormones

A

Cytoplasmic receptors

25
Q

Examples of steroid hormones

A

Hormones from GFR, Vit D, Thyroid hormones

26
Q

Receptor site if a.a. that fxn like steroid hormones

A

Nucleus

27
Q

Hormones with JAK/STAT receptors

A

GH, prolactin

28
Q

Gs receptor hormones

A

GHRH, TSH, FSH, LH, ACTH, V2

29
Q

Gi receptor hormones

A

“I-SSTD2”

SST (somatostatin), Dopamine (D2)

30
Q

Gq receptor hormones

A

“QGOVi”

GnRH, Oxytocin, V1a & b

31
Q

Receptor of v1

A

Gq

32
Q

Receptor of v2

A

Gs

33
Q

Drug with AE of GIT and gallstones

A

Somatostatin (octreotide and lanreotide)

34
Q

Drug with AE of myalgia and arthralgia

A

Growth hormone in ADULTS

35
Q

GnRH analog that is administered through NASAL SPRAY

A

Nafarelin

36
Q

Drugs that have FLARES as AE

A

GnRH analogs (-RELINs)

37
Q

Drugs with menopause-like symptoms as AE

A

GnRH antagonists

38
Q

Most common AE of GnRH antagonists

A

Nausea and headaches!!! Not menopause-like symptoms okay!! Pls remember diz

39
Q

Primary regulator of spermatogenesis

A

FSH

40
Q

Main stimulus for testosterone synthesis in leydig cells

A

LH

41
Q

DOC for anovulation. If it fails, what’s given next?

A

Clomiphene, if it fails, give gonadotrophic hormones (hMG or UFSH, and hcg)

42
Q

Drug with multiple pregnancies as AE

A

Gonadotropic hormones

Mimic FSH -menotropin, urofollitropin, rFSH
LH - hCG+, rhCG

43
Q

Drug with ovarian hyperstimulation syndrome (OHSS) as AE

A

Gonadotropic hormones

Mimic FSH -menotropin, urofollitropin, rFSH
LH - hCG+, rhCG

44
Q

Dopamine agonist that is Non-ergot agent

A

Quinagolide

45
Q

DOC for acromegaly with hyperprolactinemia

A

Dopamine

46
Q

Not recommended dopa agonist for inhibiting physiologic lactation…..and WHY

A

Bromocriptine coz may cause stroke and coronary thrombosis

47
Q

Effects of oxytocin

@high concentrations
@therapeutic conc

A

@high: weak antidiuretic and pressor effects

@thera: uterine contractions

48
Q

Administration of OXYTOCIN should be done through ____ in augmentation?

A

IV

49
Q

Administration of OXYTOCIN should be done through ____ in postpartum hemorrhage?

A

IV/IM

50
Q

Administration of OXYTOCIN should be done through ____ in induction and reinforcement of labor/post term preg and fetal death?

A

IV

51
Q

Drug used for tocolysis

A

Atosiban (oxytocin antag)

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