Humoral Immunity Flashcards
1
Q
What is CD154?
A
It is the same CD40L, receptor on T cell that activates B cells. When it is activated it releases IL-4
2
Q
What happens if you do not have CD-40- CD154 interaction?
A
B cells will not undergo isotype switching to TD antigen. They will develop Hyper IgM syndrome (lots of IgMs but lack normal levels of IgG or IgA)
3
Q
What is the function of the C3b molecule?
A
The presence of C3b on the surface of a microbe marks it as foreign and targets it for destruction.
C3b will help to generate C5 convertase
