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مقدمات گوارش +مجاری صفراوی > IBD > Flashcards

IBD Flashcards

1
Q

Indeterminate colitis

A

A type of IBD in which distinguishing between UC and CD is impossible

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2
Q

Increase risk of both CD +UC

A

Fat diet
Low birth rank
Good hygiene
Campylobacter +salmonella +shigella

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3
Q

Decreased risk of both CD+UC

A

Increased omega 3 intake and decreased omega 6 intake
عدد اخوة اكثر
Breast feeding 🤱
Lactobacillus
H.pylori
Parasitic worms

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4
Q

Increases incidence of CD

A

Antibiotics
Appendectomy
منزل اصغر
Refined sugar
Smoking
M.avium tuberculosis +measles +E.coli
Mono+Dizygotic twins

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5
Q

Increased incidence of UC

A

شير مانگا
الكثير من اخوة اكبر
Sleep duration فرة زياي يان كةم
Monozygotic twins

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6
Q

Decreased incidence of CD

A

Fibers

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7
Q

Decreased incidence of UC

A

Appendectomy
Smoking 🚬

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8
Q

Genetic factors

A

The disease related gene is NOD-2
HLA DRB-1……extensive colitis +extra intestinal manifestations.
Anatomic site and clinical type of CD is concordant within families

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9
Q

Diarrhea pattern in proctitis

A

Nocturnal and/or postprandial

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10
Q

Tympany or tympanites (sometimes tympanism or tympania), AKAmeteorism

A

is a medical condition in which excess gas accumulates in the gastrointestinal tract and causes abdominal distension.

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11
Q

Ulcerative colitis/elderly/most common findings

A

Diarrhea +weight loss

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12
Q

Hematochezia

A

More common in UC

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13
Q

Tenesmus +passage of mucus

A

Proctitis

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14
Q

Crohn

A

خراجات
Fibrosis
Anal stenosis
Significant perineal disease

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15
Q

Fistula in crohns

A

Resolve by fibrosis

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16
Q

Creeping fat

A

A delicate circumferential extension of the mesenteric fat around the small and large intestinal serosa
which classically occurs in Crohn’s disease,
but is also described in renal transplant patients

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17
Q

Cobblestone” appearance

A

Stellate ulcerations and islands of normal mucosa (active disease)

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18
Q

Palpable inflammatory mass in right lower quadrant

A

Crohn’s

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19
Q

Gross blood in stool + mucus

A

More in UC

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20
Q

Frequently
ANCA positive more in …………
ASCA positive more in …………

*ايمانويل ماكرون يحب أكل الئاسك😉😉😉😉😉😉😉😉😉😉😉😉

A

UC
CD

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21
Q

من يسكن البحر ويحبه الناس ……………

من يستجيب للمضادات الحيوية وقد يعود بعد الجراحة……………

A

سبونج بوب سكويرپانتس
ايمانويل ماكرون

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22
Q

One of IBD differential diagnosis

Distal ileal and cecal involvement predominates.
Symptoms of small-bowel obstruction and tender abdominal mass

A

Mycobacterium infection

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23
Q

One of differential diagnosis of IBD

Occurs mainly in terminal ileum
Mucosal ulceration,
neutrophil invasion,
thickening of ileal wall

A

Yersinia entercolitica infection

24
Q

One of Differential diagnosis of IBD

Can mimic endoscopic appearance of severe UC
Can cause relapse of established UC

A

Campylobacter colitis

25
Q

One of differential diagnosis of IBD

Necrosis and perforation

Infection with …………

A

CMV

26
Q

One of differential diagnosis of IBD

Collagenous colitis

اسفنج= ئاو 😉😉😉😉😉😉

A

Female more /Elderly more

Main symptom is chronic watery diarrhea

ژن پير اسفنج ها دةسي

27
Q

One of differential diagnosis of IBD

Diversion colitis

A

Inflammatory process that arises in segments of large intestine excluded from fecal stream

Usually occurs in patients with ileostomy or colostomy when mucus fistula or Hartmann’s pouch created

Mucus or bloody discharge from rectum

28
Q

Radiation colitis/enteritis can lead to

A

Fistula

29
Q

Fecal calprotectin levels

Rise in both UC + CD

A

Correlate well with histological inflammation
Predict relapses
Detect pouchitis

30
Q

Rare elevated C-reactive protein level

لأن خوةي شكل C دةد 😁😁😁😁😁

A

In proctitis and proctosigmoiditis

31
Q

These autoantibodies are not useful in diagnosis and management of IBD.

A

anti–goblet-cell autoantibodies
pancreatic autoantibodies

32
Q

pANCA in IBD

A

More in UC and distinctive from those in vasculitis

May also identify specific disease phenotypes:- ppp😁ppp😁ppp😁ppp😁
Pancolitis
Early surgery
Pouchitis
Inflammation of pouch after ileal pouch–anal anastomosis (IPAA)
Primary sclerosing cholangitis

In CD
Associated with colonic disease that resembles UC

33
Q

ASCA

A

May help decide whether patients with indeterminate colitis should undergo IPAA.

34
Q

Laboratory tests in both UC +CD

A

Hypo-albuminemia
Decreased hemoglobin
Leukocytosis
Increased fecal calprotectin levels
Increased platelet

35
Q

Sigmoidoscopy in UC

A

Assesss disease activity

36
Q

Single contrast barium enema /UC

A

Deep ulcerations can appear as “collar-button” ulcers.
Psedupolyps

37
Q

Plain supine radiographic film of abdomen Should be done in severe attack
Margin of the colon becomes edematous and irregular.
Colon thickening and toxic dilation can both be seen.

A

Should be done in severe attack

Colon thickening and toxic dilation can both be seen.

38
Q

Not as helpful as endoscopy and barium enema in making diagnosis of UC

A

CT-scan

39
Q

Aphthae
Stellate ulcer
Longitudinal ulcer

A

CD

40
Q

string sign”
Represents long areas of circumferential inflammation and fibrosis, resulting in long segments of luminal narrowing

A

InCD

41
Q

Skeletal manifestations m:-

١/في الحالات الشديدة colectomy

٢/لايستجيب مع غلوكوكورتيكويدات او قطع القولون

A

Peripheral arthritis

Ankylosing spondylitis

42
Q

Cholelithiasis
More common in

A

CD

43
Q

علاج UC +CD

A

اهرامات سلايد 163+164

44
Q

Maintenance therapy

UC …………
CD ,inflammatory …………,fistualizing…………

A

ASA+6MP or Azathio….

ASA+6MP or Azathio
+انفلكسي
+سيرتولي
+بوديسونايد

AB +6MPor Azathio….
+انفلكسي
+ادالي موماب

45
Q

Glucocorticoids
play …………role in maintenance therapy

Examples

A

No

Oral /پريدنيزون
Parenteral/مثيل پريدنيزولون+هايدروكورتيزون+ادينوكورتيكوتروپيك هورمون
Topical/hydrocortisone enema or foams

46
Q

…………no role in treatment of UC
Used in treatment of pouchitis after colectomy or IPAA

A

AB

47
Q

Use as first-line drugs in perianal and fistulous CD.
Use as second-line drugs in active CD after 5-ASA agents.

A

AB

میترونیدازول /سیپروفلوکساسین/ریفاکزمین

48
Q

Commonly used in glucocorticoid-dependent IBD
Successfully used as glucocorticoid-sparing agents
Have role in maintenance therapy

A

6MP or Azathio…..

49
Q

Can be alternative to colectomy

A

Cyclosporin IV

50
Q

Treatment of inflammatory CD
Specially ileum + R.colon

A

بودی سوناید

51
Q

Phosphatidylcholine

A

Reduced steroid dependence with chronic glucocorticoid-refractory UC

52
Q

Colon cancer in elderly

A

Risk is same as in general population.

53
Q

Metastatic CD

A

Rare and defined by cutaneous granuloma formation

54
Q

A transverse colon with a diameter of >5–6 cm
And loss of haustrations

A

Toxic megacolon
Can be triggered by electrolyte abnormalities and narcotics

55
Q

Most dangerous of local complications

Toxic megacolon is a risk factor

A

Perforations

56
Q

Strictures in UC

Strictures that are impassable with the colonoscope ……….

One-third of strictures occur in ………
Should be surveyed endoscopically for carcinoma

A

یجعلنا نشک ب neoplasia

should be presumed malignant until proved otherwise.

rectum.

57
Q

PSC is risk factor for …………colon

A

Cancer

مقدمات گوارش +مجاری صفراوی (16 decks)

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