immune system Flashcards

study guide for lecture exam #2

1
Q

what is the function of the immune system?

A

resist disease

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2
Q

what are the two main classes of immunity?

A
  1. innate defenses
  2. adaptive defenses
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3
Q

what are the differences between innate defenses and adaptive defenses?

A
  • innate defenses are non-specific and functions right away
  • adaptive defenses are long lasting and take longer to function
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4
Q

what is the first line of defense of the innate immune system and what type(s) of barrier is it?

A

surface barriers; it is a physical & chemical barrier

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5
Q

what are the two physical and chemical barriers that make up the first line of defense; what are their functions?

A

skin & mucous membrane; both secrete chemicals

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6
Q

what is the second line of defense of the innate immune system?

A

internal defenses

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7
Q

what are the 5 cells/chemical(s) that make up the second line of defense?

A
  1. phagocytic cells
  2. natural killer cells (NK cells)
  3. inflammation
  4. antipathogenic proteins
  5. fever
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8
Q

list the 5 types of leukocytes

A
  1. neutrophils
  2. lymphocytes
  3. monocytes
  4. eosinophils
    5.. basophils
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9
Q

what are the functions of neutrophils?

A

phagocytosis

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10
Q

what are the functions of lymphocytes?

A

produce antibodies

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11
Q

what are the functions of monocytes?

A

phagocytosis

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12
Q

what are the functions of eosinophils?

A

help kill off parasitic worms

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13
Q

what are the functions of basophils?

A

help create inflammation process, allergic reaction

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14
Q

define inflammation

A

body’s way to protect itself after injury or help fight infection

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15
Q

what are the 4 hallmarks of inflammation?

A
  • edema (swelling)
  • redness
  • heat (hot to touch)
  • painful
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16
Q

what are the steps to an inflammation response?

A
  • initiated by proinflammatory chemicals
  • chemicals trigger vasodilation, increased capillary permeability, recruitment of immune cells to the site
  • the contents of exudate (inflammatory fluid & cellular/protein mixture) help eliminate the pathogen and promote healing
17
Q

what are interferons (IFNs)?

A

protein cytokines produced in response to intracellular pathogens; primarily viruses, but also intracellular bacteria

18
Q

what are the functions of interferons?

A

warns nearby cells of virus infection

19
Q

what is the main type of leukocyte in adaptive immunity?

A

lymphocytes

20
Q

what is the function of adaptive immunity?

A

destroys specific invading pathogens and any toxic molecules they produce

21
Q

what is an antigen?

A

a surface molecule

22
Q

what do antigens do?

A

they can interact with immune cells (on our own cells - “self” // on pathogens - “non-self”)

23
Q

what are antibodies?

A

immune proteins

24
Q

what are antibodies made by?

A

B-Cells

25
Q

what are the characteristics of primary immune responses?

A
  • small number of antibodies
  • symptoms
26
Q

what are the characteristics of secondary immune responses?

A
  • quick & large number of antibodies
  • produced due to memory cells
  • no symptoms
27
Q

what is the definition of hypo-immunity?

A

immune system working less than it should

28
Q

give an example of hypo-immunity?

A

aids caused by HIV (targets & destroys t-cells)

29
Q

what is the definition of hyper-immunity?

A

immune system working more than it should

30
Q

give an example of hyper-immunity?

A

allergies & autoimmune disease

31
Q

define allergies

A

immune system overreacts to non-pathogenic pathogens

32
Q

define autoimmune disease

A

immune cells attack own cells