immune system infection diseases Flashcards

1
Q

what is an antigen

A

protein component of pathogen that elicits the immune response

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2
Q

what are specialized cells

A

lymphocytes and phagocytes for response to a foreign substance

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3
Q

what are antibodies or immunoglobulins

A

proteins that destroy antigens

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4
Q

what are biological factors causing immune response

A

foreign substance or pathogen

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5
Q

how do PTs treat infection diseases

A

treat s/sx of infection and timing of infection

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6
Q

what does the immune system do

A

protects “self” from “nonself” which is necessary for survival

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7
Q

what does non self refer to

A

external or internal

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8
Q

what does self refer to

A

autoimmune response

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9
Q

what role do tissue and organs play in immune response

A

recognition and elimination of foreign pathogen

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10
Q

immune system dysfunction leads to

A

illness and disease  varying physiologic change, clinical expression, and FUNCTIONAL DEFICITS  severity

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11
Q

what does antigen specific mean

A

adaptive

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11
Q

what does nonspecific mean

A

innate

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11
Q

non specific immunity characteristics

A

response is antigen independent
there is immediates maximal response
not antigen specific
exposure results in no immunologic memory

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12
Q

specific immunity characteristics

A

response is antigen dependent
there is a lag time between exposure and maximal response
antigen specific
exposure results in immunologic memory

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13
Q

adaptive immunity or antigent specific response can be further broken down into humoral which is

A

antibody mediated = B cells

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14
Q

adaptive immunity can be further broken down into cell mediated which consists of

A

T cells

15
Q

humoral means

A

B cells have been triggered to produce antibodies

15
Q

cell mediated means

A

cell communicates with/triggers cell, no antibody

16
Q

cells of the immune system

A

monocytes
lymphocytes
granulocytic cells (neutrophils, basophils)

17
Q

innate immune system cells

A

macrophage (primary WBC)
neutrophil
basophil
dendritic
natural killer
T cell

18
Q

adaptive immunity cells

A

B cell
T cell

19
Q

adaptive response immunity

A

Antibody-Mediated & Cell-Mediated: provides specificity and memory of previous antigen encounters (vaccinations

20
Q

innate response immunity

A

generalized immune response includes epithelial barriers, mucociliary clearance, phagocytic cells, and complement proteins present antigens to antigen specific immune response

21
Q

monocytes

A

circulate in the blood

22
Q

macrophage

A

present in tissue

23
Q

lymphoid organs

A

Macrophage (innate) present antigens to T lymphocytes (adaptive)

24
Q

Monocytes and Macrophages contain receptors that facilitate their action in the nonspecific pathway engulf and destroy a pathogen and antigen-specific pathway: trigger T cells

A

Present the foreign material antigen to T lymphocytes
-T cells trigger the release of cytokines
- Cytokine release causes B lymphocytes to produce antibodies
- Antibody molecules released

25
Q

leukocytes (WBC) include following cells

A

lymphocytes (T and B)
granulocytes (eosinophils, basophils, neutrophils)
monocytes

26
Q

B lymphocutes

A

10-15%

26
Q

T lymphocytes

A

70-80% of blood lympocytes

27
Q

T cells mature in the

A

thymus

27
Q

mature T cells migrate to the

A

lymphoid tissues

28
Q

lymph fluid

A

collection of interstitial fluid by way of lymph capillaries, cleaned by lymphocytes in the lymph nodes

29
Q

T cells push and pull of pressure

A

T Cells recirculate between the blood and the lymph fluid via hydrostatic and osmotic pressures

30
Q

t lymphocytes

A

are bridge between innate and adaptive immunity
often called antigen speficic cell mediated
link between phagocutic activity and B cell activation

31
Q
A