Immunisation Flashcards
What are the types of vaccines?
Live attenuated
Inactivated
Detoxified exotoxin
Subunit of micro-organism
Examples of live attenuated?
MMR BCG VZV Yellow fever Smallpox
Examples of inactivated?
Pertussis
Hep A
Rabies
Influenza
How are detoxified exotoxin vaccines made
Toxins treated with formalin = toxoid
Diptheria and tetanus
What are examples of subunit vaccines?
Pertussis Meningococcus Pneumococcus Thyphoid Anthrax Hep B
How are recombinant vaccines made?
DNA segment - removed and purified H and N surface antigens - into yeast and fermented = HBsAg produced
Hep B
What is the 6 in 1 vaccine?
diptheria Tetanus Bordetella pertussis Polio Heamophilus infulenza b Hep B
What is the UK childhood schedule?
2 m = 6 in 1, pneumococcal + rotavirus + men B
3 m = 6 in 1 + rota
4 m = 6 in 1 + pneumococcal + men B
15 m = MMR
What is passive immunisation?
Human normal immunoglobin
Disease specific immunoglobulin
What is human normal immunoglobin?
Ab against hep A, rubella and measles
Treatment of myasthenia gravis
What is disease specific immunoglobulin?
Post expousre Hep b rabies tetanus VZV Diptheria Botulinum
What are some common travellers immunisations?
Tetanus Polio Typhoid Hep A yellow fever Cholera Diptheria
What is the ABCD approach of malaria prevention?
Awareness
Bite prevention
Chemoprophylaxis
Diagnosis and treatment
