Immunodeficiency Flashcards

1
Q

What are the primary lymphoid tissues?

A

Bone Marrow

Thymus

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2
Q

What are the secondary lymphoid tissues?

A

Spleen
Lymph Nodes
Tonsils
Payer’s Patches

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3
Q

What are the main consequences of immuno-deficiency?

A

Infection

Cancer

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4
Q

What are the main consequences of hyperimmunity?

A

Auto-immune

Allergy

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5
Q

What are the primary immunodeficiencies?

A

Inherited

Congenital

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6
Q

What are secondary immunodeficiencies?

A

Acquired

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7
Q

Give an example of a secondary immunodeficiency

A
HIV
Steroid use
Splenectomy
Leukaemia/Lymphoma
Malnutrition
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8
Q

Give an example of a primary immunodeficiency

A
Severe Combined Immunodeficiency (inherited stem cell defect)
DiGeorge Syndrome (defect of development of pharyngeal arches)
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9
Q

What are the antibody isotypes?

A

IgM (Pentamers)
IgG (Monomers)
IgA
IgE (Monomers)

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