Immunology Flashcards

1
Q

What cells in the epidermis are involved with the immune response?

A

Keratinocytes
Langerhans cells
T cells

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2
Q

Which type(s) of T cell is found in the epidermis?

A

CD8+

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3
Q

Which type(s) of T cells is found in the dermis?

A

CD4+ and CD8+

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4
Q

Which type of CD4 cells is associated with psoriasis

A

Th1

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5
Q

Which type of CD4 cells is associated with atopic dermatitis

A

Th2

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6
Q

Which type of CD4 cells is associated with psoriasis and atopic dermatitis

A

Th17

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7
Q

What do keratinocytes produce to aid with immune response?

A

Antimicrobial peptides
Cytokines
Chemokines

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8
Q

What types of dendritic cell are found in the dermis?

A

Dermal DC

Plasmacytoid DC

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9
Q

What is the function of Dermal DCs?

A

Antigen presenting

Secreting cytokines/ chemokines

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10
Q

What is the function of plasmacytoid DCs?

A

Produce IFNa

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11
Q

Type 1 hypersensitivity mediate by

A

IgE

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12
Q

Type 2+3 hypersensitivity mediate by

A

IgG +IgM

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13
Q

Type 4 hypersensitivity mediate by

A

Th1

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