Immunology Flashcards
What cells in the epidermis are involved with the immune response?
Keratinocytes
Langerhans cells
T cells
Which type(s) of T cell is found in the epidermis?
CD8+
Which type(s) of T cells is found in the dermis?
CD4+ and CD8+
Which type of CD4 cells is associated with psoriasis
Th1
Which type of CD4 cells is associated with atopic dermatitis
Th2
Which type of CD4 cells is associated with psoriasis and atopic dermatitis
Th17
What do keratinocytes produce to aid with immune response?
Antimicrobial peptides
Cytokines
Chemokines
What types of dendritic cell are found in the dermis?
Dermal DC
Plasmacytoid DC
What is the function of Dermal DCs?
Antigen presenting
Secreting cytokines/ chemokines
What is the function of plasmacytoid DCs?
Produce IFNa
Type 1 hypersensitivity mediate by
IgE
Type 2+3 hypersensitivity mediate by
IgG +IgM
Type 4 hypersensitivity mediate by
Th1